7ZG2
 
 | | BRD4 in complex with Acetyl-Lys | | 分子名称: | (2S)-2,6-diacetamido-N-methyl-hexanamide, Bromodomain-containing protein 4, GLYCEROL | | 著者 | Turberville, S, Martin, M.P, Hope, I, Noble, M.E.M. | | 登録日 | 2022-04-01 | | 公開日 | 2022-11-23 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.18 Å) | | 主引用文献 | Mapping Ligand Interactions of Bromodomains BRD4 and ATAD2 with FragLites and PepLites─Halogenated Probes of Druglike and Peptide-like Molecular Interactions.
J.Med.Chem., 65, 2022
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6MHH
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1RZH
 | | PHOTOSYNTHETIC REACTION CENTER DOUBLE MUTANT FROM RHODOBACTER SPHAEROIDES WITH ASP L213 REPLACED WITH ASN AND ARG M233 REPLACED WITH CYS IN THE CHARGE-NEUTRAL DQAQB STATE (TRIGONAL FORM) | | 分子名称: | BACTERIOCHLOROPHYLL A, BACTERIOPHEOPHYTIN A, CARDIOLIPIN, ... | | 著者 | Xu, Q, Axelrod, H.L, Abresch, E.C, Paddock, M.L, Okamura, M.Y, Feher, G. | | 登録日 | 2003-12-24 | | 公開日 | 2004-04-13 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | X-Ray Structure Determination of Three Mutants of the Bacterial Photosynthetic Reaction Centers from Rb. sphaeroides; Altered Proton Transfer Pathways.
STRUCTURE, 12, 2004
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3OET
 | | D-Erythronate-4-Phosphate Dehydrogenase complexed with NAD | | 分子名称: | Erythronate-4-phosphate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Filippova, E.V, Wawrzak, Z, Onopriyenko, O, Savchenko, A, Edwards, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2010-08-13 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | D-Erythronate-4-Phosphate Dehydrogenase complexed with NAD
To be Published
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1PJQ
 | | Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis | | 分子名称: | ACETATE ION, S-ADENOSYL-L-HOMOCYSTEINE, Siroheme synthase, ... | | 著者 | Stroupe, M.E, Leech, H.K, Daniels, D.S, Warren, M.J, Getzoff, E.D. | | 登録日 | 2003-06-03 | | 公開日 | 2003-12-02 | | 最終更新日 | 2014-11-12 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | CysG structure reveals tetrapyrrole-binding features and novel regulation of siroheme biosynthesis.
Nat.Struct.Biol., 10, 2003
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5LX4
 | | Cys-Gly dipeptidase GliJ mutant D38H | | 分子名称: | Dipeptidase, FE (III) ION, GLYCEROL | | 著者 | Huber, E.M, Groll, M. | | 登録日 | 2016-09-20 | | 公開日 | 2017-05-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Gliotoxin Biosynthesis: Structure, Mechanism, and Metal Promiscuity of Carboxypeptidase GliJ.
ACS Chem. Biol., 12, 2017
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8OIV
 | | Monkeypox virus VP39 in complex with SAH and cap0 | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Skvara, P, Chalupska, D, Silhan, J, Klima, M, Boura, E. | | 登録日 | 2023-03-23 | | 公開日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Structural basis for RNA-cap recognition and methylation by the mpox methyltransferase VP39.
Antiviral Res., 216, 2023
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2BWE
 | | The crystal structure of the complex between the UBA and UBL domains of Dsk2 | | 分子名称: | DSK2 | | 著者 | Lowe, E.D, Hasan, N, Trempe, J.-F, Fonso, L, Noble, M.E.M, Endicott, J.A, Johnson, L.N, Brown, N.R. | | 登録日 | 2005-07-13 | | 公開日 | 2006-01-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structures of the Dsk2 Ubl and Uba Domains and Their Complex.
Acta Crystallogr.,Sect.D, 62, 2006
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3OE8
 | | Crystal structure of the CXCR4 chemokine receptor in complex with a small molecule antagonist IT1t in P1 spacegroup | | 分子名称: | (6,6-dimethyl-5,6-dihydroimidazo[2,1-b][1,3]thiazol-3-yl)methyl N,N'-dicyclohexylimidothiocarbamate, C-X-C chemokine receptor type 4, Lysozyme Chimera | | 著者 | Wu, B, Mol, C.D, Han, G.W, Katritch, V, Chien, E.Y.T, Liu, W, Cherezov, V, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR) | | 登録日 | 2010-08-12 | | 公開日 | 2010-10-27 | | 最終更新日 | 2021-10-06 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists.
Science, 330, 2010
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6MKS
 | | Cryo-EM structure of NLRC4-CARD filament | | 分子名称: | Chimera protein of NLR family CARD domain-containing protein 4 and EGFP | | 著者 | Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H. | | 登録日 | 2018-09-26 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly.
J. Biol. Chem., 293, 2018
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6SQZ
 | | Mouse dCTPase in complex with dCMPNPP | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, MAGNESIUM ION, dCTP pyrophosphatase 1 | | 著者 | Scaletti, E.R, Claesson, M, Helleday, H, Jemth, A.S, Stenmark, P. | | 登録日 | 2019-09-04 | | 公開日 | 2020-01-29 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The First Structure of an Active Mammalian dCTPase and its Complexes With Substrate Analogs and Products.
J.Mol.Biol., 432, 2020
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5LZK
 | | Structure of the domain of unknown function DUF1669 from human FAM83B | | 分子名称: | 1,2-ETHANEDIOL, IODIDE ION, Protein FAM83B | | 著者 | Pinkas, D.M, Bufton, J.C, Williams, E.P, Shrestha, L, Burgess-Brown, N.A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A, Structural Genomics Consortium (SGC) | | 登録日 | 2016-09-29 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.575 Å) | | 主引用文献 | Structure of the domain of unknown function DUF1669 from human FAM83B
To Be Published
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5M33
 | | Structural tuning of CD81LEL (space group P21) | | 分子名称: | 1,2-ETHANEDIOL, CD81 antigen | | 著者 | Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G. | | 登録日 | 2016-10-14 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
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5M38
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2IL4
 | | Crystal structure of At1g77540-Coenzyme A Complex | | 分子名称: | COENZYME A, Protein At1g77540 | | 著者 | Bitto, E, Wesenberg, G.E, Phillips Jr, G.N, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2006-10-02 | | 公開日 | 2006-10-17 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.054 Å) | | 主引用文献 | Structure of Arabidopsis thaliana At1g77540 Protein, a Minimal Acetyltransferase from the COG2388 Family.
Biochemistry, 45, 2006
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2OV2
 | | The crystal structure of the human RAC3 in complex with the CRIB domain of human p21-activated kinase 4 (PAK4) | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Ugochukwu, E, Yang, X, Elkins, J.M, Burgess-Brown, N, Bunkoczi, G, Debreczeni, J.E.D, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Doyle, D.A, Structural Genomics Consortium (SGC) | | 登録日 | 2007-02-12 | | 公開日 | 2007-03-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The crystal structure of the human RAC3 in complex with the CRIB domain of human p21-activated kinase 4 (PAK4)
To be Published
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6MJ1
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5M3T
 | | Structural tuning of CD81LEL (space group P64) | | 分子名称: | 1,2-ETHANEDIOL, CD81 antigen, CHLORIDE ION | | 著者 | Cunha, E.S, Sfriso, P, Rojas, A.L, Roversi, P, Hospital, A, Orozco, M, Abrescia, N.G. | | 登録日 | 2016-10-17 | | 公開日 | 2016-12-14 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.021 Å) | | 主引用文献 | Mechanism of Structural Tuning of the Hepatitis C Virus Human Cellular Receptor CD81 Large Extracellular Loop.
Structure, 25, 2017
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3OFV
 | | Crystal structure of peptidyl-tRNA hydrolase from Escherichia Coli, I222 crystal form | | 分子名称: | Peptidyl-tRNA hydrolase | | 著者 | Lam, R, McGrath, T.E, Romanov, V, Gothe, S.A, Peddi, S.R, Razumova, E, Lipman, R.S, Branstrom, A.A, Chirgadze, N.Y. | | 登録日 | 2010-08-16 | | 公開日 | 2011-08-17 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Crystal structure of peptidyl-tRNA hydrolase from Escherichia Coli, I222 crystal form
To be Published
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5TZL
 | | Structure of transthyretin in complex with the kinetic stabilizer 201 | | 分子名称: | 4-(7-chloro-1,3-benzoxazol-2-yl)-2,6-diiodophenol, Transthyretin | | 著者 | Connelly, S, Mortenson, D.E, Choi, S, Wilson, I.A, Powers, E.T, Kelly, J.W, Johnson, S.M. | | 登録日 | 2016-11-21 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.
Bioorg. Med. Chem. Lett., 27, 2017
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6FCV
 | | Structure of the human DDB1-CSA complex | | 分子名称: | DNA damage-binding protein 1, DNA excision repair protein ERCC-8 | | 著者 | Meulenbroek, E.M, Pannu, N.S. | | 登録日 | 2017-12-21 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.92 Å) | | 主引用文献 | TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A.
Nat Commun, 9, 2018
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8R8Q
 | | Lysosomal peptide transporter | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycosylated lysosomal membrane protein, Major facilitator superfamily domain-containing protein 1 | | 著者 | Jungnickel, K.E.J, Loew, C. | | 登録日 | 2023-11-29 | | 公開日 | 2024-05-01 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (4.08 Å) | | 主引用文献 | MFSD1 with its accessory subunit GLMP functions as a general dipeptide uniporter in lysosomes.
Nat.Cell Biol., 26, 2024
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5LTF
 | | Crystal structure of Lymphocytic choriomeningitis mammarenavirus endonuclease complexed with catalytic ions | | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L | | 著者 | Saez-Ayala, M, Yekwa, E.L, Canard, B, Ferron, F. | | 登録日 | 2016-09-06 | | 公開日 | 2017-09-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
IUCrJ, 5, 2018
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5M52
 | | Crystal structure of yeast Brr2 full-lenght in complex with Prp8 Jab1 domain | | 分子名称: | Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2 | | 著者 | Wollenhaupt, J, Absmeier, E, Becke, C, Santos, K.F, Wahl, M.C. | | 登録日 | 2016-10-20 | | 公開日 | 2016-12-07 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Interplay of cis- and trans-regulatory mechanisms in the spliceosomal RNA helicase Brr2.
Cell Cycle, 16, 2017
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4CDX
 | | Crystal structure of human Enterovirus 71 in complex with the uncoating inhibitor GPP12 | | 分子名称: | 1-(5-((3'-METHYL-[1,1'-BIPHENYL]-4-YL)OXY)PENTYL)-3-(, SODIUM ION, VP1, ... | | 著者 | De Colibus, L, Wang, X, Spyrou, J.A.B, Kelly, J, Ren, J, Grimes, J, Puerstinger, G, Stonehouse, N, Walter, T.S, Hu, Z, Wang, J, Li, X, Peng, W, Rowlands, D, Fry, E.E, Rao, Z, Stuart, D.I. | | 登録日 | 2013-11-07 | | 公開日 | 2014-02-12 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | More-Powerful Virus Inhibitors from Structure-Based Analysis of Hev71 Capsid-Binding Molecules.
Nat.Struct.Mol.Biol., 21, 2014
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