6SBP
 
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7KGG
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8Q9N
 | | Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and MITR deacetylase binding motif mutant L151V. | | 分子名称: | DIMETHYL SULFOXIDE, DNA MADS box, MEF2D protein, ... | | 著者 | Chinellato, M, Carli, A, Perin, S, Mazzocato, Y, Biondi, B, Di Giorgio, E, Brancolini, C, Angelini, A, Cendron, L. | | 登録日 | 2023-08-20 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
J.Mol.Biol., 436, 2024
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5UE6
 | | Structure of nitrite reductase AniA from Neisseria gonorrhoeae, space group I4122 | | 分子名称: | COPPER (II) ION, Nitrite reductase, SODIUM ION | | 著者 | Hamza, A, Williamson, Z.A, Reed, R.W, Sikora, A.E, Korotkov, K.V. | | 登録日 | 2016-12-29 | | 公開日 | 2017-02-01 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Peptide Inhibitors Targeting the Neisseria gonorrhoeae Pivotal Anaerobic Respiration Factor AniA.
Antimicrob. Agents Chemother., 61, 2017
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5M83
 | | Translation initiation factor 4E in complex with (RP)-m2(7,2'O)GppSpA mRNA 5' cap analog | | 分子名称: | Eukaryotic translation initiation factor 4E, GLYCEROL, [[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]oxy-sulfanyl-phosphoryl] [(2~{R},3~{R},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanyl-purin-7-ium-9-yl)-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl hydrogen phosphate | | 著者 | Warminski, M, Nowak, E, Kowalska, J, Jemielity, J, Nowotny, M. | | 登録日 | 2016-10-28 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Translation initiation factor 4E in complex with (RP)-m2(7,2'O)GppSpA mRNA 5' cap analog
To Be Published
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3NQU
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2K4F
 | | Mouse CD3epsilon Cytoplasmic Tail | | 分子名称: | T-cell surface glycoprotein CD3 epsilon chain | | 著者 | Xu, C, Call, M.E, Schwieters, C.D, Schnell, J.R, Gagnon, E.E, Wucherpfennig, K.W, Chou, J.J. | | 登録日 | 2008-06-07 | | 公開日 | 2008-12-02 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Regulation of T Cell Receptor Activation by Dynamic Membrane Binding of the CD3varepsilon Cytoplasmic Tyrosine-Based Motif.
Cell(Cambridge,Mass.), 135, 2008
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5CGW
 | | CRYSTAL STRUCTURE OF Fox-4 cephamycinase mutant Y150F | | 分子名称: | ACETATE ION, Beta-lactamase, ZINC ION | | 著者 | Malashkevich, V.N, Toro, R, Lefurgy, S, Almo, S.C. | | 登録日 | 2015-07-09 | | 公開日 | 2016-02-03 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | FOX-4 cephamycinase: an analysis of structure and function.
Antimicrob.Agents Chemother., 2015
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4MIK
 | | Crystal Structure of hPNMT in Complex with bisubstrate inhibitor (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-(((2-(((7-nitro-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl)amino)ethyl)thio)methyl)tetrahydrofuran-3,4-diol | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 9-{5-S-[2-({[(3S)-7-nitro-1,2,3,4-tetrahydroisoquinolin-3-yl]methyl}amino)ethyl]-5-thio-alpha-L-lyxofuranosyl}-9H-purin-6-amine, Phenylethanolamine N-methyltransferase | | 著者 | Bart, A.G, Scott, E.E. | | 登録日 | 2013-08-31 | | 公開日 | 2014-09-10 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.9506 Å) | | 主引用文献 | To be published
To be Published
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1TZL
 | | Crystal Structure of Pyranose 2-Oxidase from the White-Rot Fungus Peniophora sp. | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, pyranose oxidase | | 著者 | Bannwarth, M, Bastian, S, Heckmann-Pohl, D, Giffhorn, F, Schulz, G.E. | | 登録日 | 2004-07-10 | | 公開日 | 2004-10-19 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Crystal structure of pyranose 2-oxidase from the white-rot fungus peniophora sp.
Biochemistry, 43, 2004
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6SD2
 | | Structure of the RBM2inner region of the Salmonella flagella MS-ring protein FliF with 21-fold symmetry applied. | | 分子名称: | Flagellar M-ring protein | | 著者 | Johnson, S, Fong, Y.H, Deme, J.C, Furlong, E.J, Kuhlen, L, Lea, S.M. | | 登録日 | 2019-07-26 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Symmetry mismatch in the MS-ring of the bacterial flagellar rotor explains the structural coordination of secretion and rotation.
Nat Microbiol, 5, 2020
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5MIM
 | | Xray structure of human furin bound with the 2,5-dideoxystreptamine derived small molecule inhibitor 1n | | 分子名称: | 1-[(1~{R},2~{R},4~{S},5~{S})-2,4-bis(4-carbamimidamidophenoxy)-5-[(4-carbamimidamidophenyl)amino]cyclohexyl]guanidine, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Dahms, S.O, Guan-Sheng, J, Than, M.E. | | 登録日 | 2016-11-28 | | 公開日 | 2017-05-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural Studies Revealed Active Site Distortions of Human Furin by a Small Molecule Inhibitor.
ACS Chem. Biol., 12, 2017
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7NF9
 | | N-terminal C2H2 Zn-finger domain of Clamp | | 分子名称: | Chromatin-linked adaptor for MSL proteins, isoform A, ZINC ION | | 著者 | Mariasina, S.S, Bonchuk, A.N, Tikhonova, E.A, Efimov, S.V, Maksimenko, O.G, Georgiev, P.G, Polshakov, V.I. | | 登録日 | 2021-02-05 | | 公開日 | 2021-12-29 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural basis for interaction between CLAMP and MSL2 proteins involved in the specific recruitment of the dosage compensation complex in Drosophila.
Nucleic Acids Res., 50, 2022
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7ZPN
 | | Crystal Structure of IscR from Dinoroseobacter shibae | | 分子名称: | GLYCEROL, HTH-type transcriptional regulator, SULFATE ION | | 著者 | Lukat, P, Ploetzky, L, Blankenfeldt, W, Jahn, D, Haertig, E. | | 登録日 | 2022-04-28 | | 公開日 | 2023-04-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Dinoroseobacter shibae IscR homolog acts as a repressor for iron acquisition genes
To Be Published
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1FAK
 | | HUMAN TISSUE FACTOR COMPLEXED WITH COAGULATION FACTOR VIIA INHIBITED WITH A BPTI-MUTANT | | 分子名称: | CALCIUM ION, PROTEIN (5L15), PROTEIN (BLOOD COAGULATION FACTOR VIIA), ... | | 著者 | Zhang, E, St Charles, R, Tulinsky, A. | | 登録日 | 1998-12-28 | | 公開日 | 1999-12-03 | | 最終更新日 | 2023-05-31 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure of extracellular tissue factor complexed with factor VIIa inhibited with a BPTI mutant.
J.Mol.Biol., 285, 1999
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2C37
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8PQO
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1W8S
 | | The mechanism of the Schiff Base Forming Fructose-1,6-bisphosphate Aldolase: Structural analysis of reaction intermediates | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, FRUCTOSE-BISPHOSPHATE ALDOLASE CLASS I | | 著者 | Lorentzen, E, Hensel, R, Siebers, B, Pohl, E. | | 登録日 | 2004-09-27 | | 公開日 | 2005-03-23 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Mechanism of the Schiff base forming fructose-1,6-bisphosphate aldolase: structural analysis of reaction intermediates.
Biochemistry, 44, 2005
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6SBS
 | | YtrA from Sulfolobus acidocaldarius, a GntR-family transcription factor | | 分子名称: | Regulatory protein | | 著者 | Lemmens, L, Valegard, K, Lindas, A.C, Peeters, E, Maes, D. | | 登録日 | 2019-07-22 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | | 主引用文献 | YtrASa, a GntR-Family Transcription Factor, Represses Two Genetic Loci Encoding Membrane Proteins inSulfolobus acidocaldarius.
Front Microbiol, 10, 2019
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5MI4
 | | BtGH84 mutant with covalent modification by MA3 | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, O-GlcNAcase BT_4395, ... | | 著者 | Darby, J.F, Davies, G.J, Hubbard, R.E. | | 登録日 | 2016-11-27 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Increase of enzyme activity through specific covalent modification with fragments.
Chem Sci, 8, 2017
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5MJ3
 | | INTERLEUKIN-23 COMPLEX WITH AN ANTAGONISTIC ALPHABODY, CRYSTAL FORM 1 | | 分子名称: | ALPHABODY MA12, Interleukin-12 subunit beta, Interleukin-23 subunit alpha, ... | | 著者 | Desmet, J, Verstraete, K, Bloch, Y, Lorent, E, Wen, Y, Devreese, B, Vandenbroucke, K, Loverix, S, Hettmann, T, Deroo, S, Somers, K, Hendrikx, P, Lasters, I, Savvides, S.N. | | 登録日 | 2016-11-29 | | 公開日 | 2017-01-11 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Structural Basis Of Il-23 Antagonism By An Alphabody Protein Scaffold.
Nat Commun, 5, 2014
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6F55
 | | Complex structure of PACSIN SH3 domain and TRPV4 proline rich region | | 分子名称: | PACSIN 3, PRR | | 著者 | Glogowski, N.A, Goretzki, B, Diehl, E, Duchardt-Ferner, E, Hacker, C, Hellmich, U.A. | | 登録日 | 2017-11-30 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis of TRPV4 N Terminus Interaction with Syndapin/PACSIN1-3 and PIP2.
Structure, 26, 2018
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5MMA
 | | Crystal structure of the Prototype Foamy Virus (PFV) intasome in complex with magnesium and the INSTI XZ379 (compound 5'g) | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA (5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3'), ... | | 著者 | Maskell, D.P, Pye, V.E, Cherepanov, P. | | 登録日 | 2016-12-09 | | 公開日 | 2017-08-02 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structure-Guided Optimization of HIV Integrase Strand Transfer Inhibitors.
J. Med. Chem., 60, 2017
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1FJ3
 | | THERMOLYSIN (50% ACETONE SOAKED) | | 分子名称: | ACETONE, CALCIUM ION, DIMETHYL SULFOXIDE, ... | | 著者 | English, A.C, Groom, C.R, Hubbard, R.E. | | 登録日 | 2000-08-07 | | 公開日 | 2001-04-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Experimental and computational mapping of the binding surface of a crystalline protein.
Protein Eng., 14, 2001
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6SID
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