PDB: 37044 件ウェブページステータス検索Chemie searchBIRD

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3ZKX	TERNARY BACE2 XAPERONE COMPLEX 分子名称: BETA-SECRETASE 2, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Kuglstatter, A, Banner, D.W, Benz, J, Bertschinger, J, Burger, D, Cuppuleri, S, Debulpaep, M, Gast, A, Grabulovski, D, Gsell, B, Hilpert, H, Huber, W, Kusznir, E, Laeremans, T, Matile, H, Rufer, A, Schlatter, D, Steyeart, J, Stihle, M, Thoma, R, Weber, M, Ruf, A. 登録日 2013-01-25 公開日 2013-05-29 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 Mapping the Conformational Space Accessible to Bace2 Using Surface Mutants and Co-Crystals with Fab-Fragments, Fynomers, and Xaperones Acta Crystallogr.,Sect.D, 69, 2013
4GZM	Crystal structure of RAC1 F28L mutant 分子名称: 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, Ras-related C3 botulinum toxin substrate 1 著者 Ha, B.H, Boggon, T.J. 登録日 2012-09-06 公開日 2012-12-12 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 RAC1P29S is a spontaneously activating cancer-associated GTPase. Proc.Natl.Acad.Sci.USA, 110, 2013
4GZG	Crystal structures of DHPA-CO complex 分子名称: CARBON MONOXIDE, Dehaloperoxidase A, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Zhao, J, Franzen, S. 登録日 2012-09-06 公開日 2013-09-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 The role of distal histidine in carbonmonoxide DHP structure To be Published
4GZO	N2 neuraminidase of A/Tanzania/205/2010 H3N2 in complex with hepes 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Zhu, X, Wilson, I.A. 登録日 2012-09-06 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
4BVW	Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV. 分子名称: 1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid, 1,2-ETHANEDIOL, APOLIPOPROTEIN(A), ... 著者 Sandmark, J, Althage, M, Andersson, G.M.K, Antonsson, T, Blaho, S, Bodin, C, Bostrom, J, Chen, Y, Dahlen, A, Eriksson, P.O, Evertsson, E, Fex, T, Fjellstrom, O, Gustafsson, D, Hallberg, C, Hicks, R, Jarkvist, E, Johansson, C, Kalies, I, Kang, D, Svalstedt Karlsson, B, Kartberg, F, Legnehed, A, Lindqvist, A.M, Martinsson, S.A, Moberg, A, Petersson, A.U, Ridderstrom, M, Thelin, A, Tigerstrom, A, Vinblad, J, Xu, B, Knecht, W. 登録日 2013-06-28 公開日 2014-07-16 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Small Molecules Used to Decipher the Pathophysiological Roles of the Kringle Domains Kiv-7, - 10 and Kv of Apolipoprotein(A) To be Published
4GZX	N2 neuraminidase D151G mutant of A/Tanzania/205/2010 H3N2 in complex with human sialic acid receptor 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Zhu, X, Wilson, I.A. 登録日 2012-09-06 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
3QJB	Human Hemoglobin A Mutant Alpha H58L Carbonmonoxy-Form 分子名称: CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... 著者 Birukou, I, Soman, J, Olson, J.S. 登録日 2011-01-28 公開日 2011-02-16 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Determination of Pathways for Oxygen Binding to Human HbA Thesis
4GZS	N2 neuraminidase D151G mutant of a/Tanzania/205/2010 H3N2 in complex with hepes 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Zhu, X, Wilson, I.A. 登録日 2012-09-06 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. J.Virol., 86, 2012
4H07	Complex of G65T Myoglobin with Phenol in its Proximal Cavity 分子名称: 1,2-ETHANEDIOL, Myoglobin, PHENOL, ... 著者 Lebioda, L, Lovelace, L.L, Celeste, L.R, Huang, X, Wang, C, Shengfang, S, Dawson, J.H. 登録日 2012-09-07 公開日 2012-11-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.14 Å) 主引用文献 Complex of myoglobin with phenol bound in a proximal cavity. Acta Crystallogr.,Sect.F, 68, 2012
4H1E	Structure of BACE-1 Bound to (7aR)-6-benzoyl-7a-(4-(3-cyanophenyl)thiophen-2-yl)-3-methyl-4-oxohexahydro-1H-pyrrolo[3,4-d]pyrimidin-2(3H)-iminium 分子名称: 3-{5-[(2E,4aR,7aR)-6-benzoyl-2-imino-3-methyl-4-oxooctahydro-7aH-pyrrolo[3,4-d]pyrimidin-7a-yl]thiophen-3-yl}benzonitrile, Beta-secretase 1 著者 Orth, P. 登録日 2012-09-10 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation. J.Med.Chem., 55, 2012
3RN3	SEGMENTED ANISOTROPIC REFINEMENT OF BOVINE RIBONUCLEASE A BY THE APPLICATION OF THE RIGID-BODY TLS MODEL 分子名称: RIBONUCLEASE A, SULFATE ION 著者 Howlin, B, Moss, D.S, Harris, G.W, Palmer, R.A. 登録日 1991-10-30 公開日 1991-10-31 最終更新日 2017-11-29 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Segmented anisotropic refinement of bovine ribonuclease A by the application of the rigid-body TLS model. Acta Crystallogr.,Sect.A, 45, 1989
4C3Z	Nucleotide-free crystal structure of nucleotide-binding domain 1 from human MRP1 supports a general-base catalysis mechanism for ATP hydrolysis. 分子名称: MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1, SULFATE ION 著者 Chaptal, V, Gueguen-Chaignon, V, Magnard, S, Falson, P, Di Pietro, A, Baubichon-Cortay, H. 登録日 2013-08-28 公開日 2014-09-10 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Nucleotide-Free Crystal Structure of Nucleotide-Binding Domain 1 from Human Abcc1 Supports a 'General-Base Catalysis' Mechanism for ATP Hydrolysis. Biochem.Pharm., 3, 2014
2XS2	Crystal structure of the RRM domain of mouse Deleted in azoospermia-like in complex with RNA, UUGUUCUU 分子名称: 5'-R(*UP*UP*GP*UP*UP*CP*UP*U)-3', DELETED IN AZOOSPERMIA-LIKE, ZINC ION 著者 Jenkins, H.T, Edwards, T.A. 登録日 2010-09-24 公開日 2011-10-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Kinked beta-strands mediate high-affinity recognition of mRNA targets by the germ-cell regulator DAZL. Proc. Natl. Acad. Sci. U.S.A., 108, 2011
4H6V	Structure of Patellamide maturation protease PatA 分子名称: Subtilisin-like protein 著者 Nair, S.K, Agarwal, V. 登録日 2012-09-19 公開日 2012-10-03 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structures of cyanobactin maturation enzymes define a family of transamidating proteases. Chem.Biol., 19, 2012
4C9M	Structure of substrate free, glycerol bound wild type CYP101D1 分子名称: CYTOCHROME P450, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE 著者 Batabyal, D, L Poulos, T. 登録日 2013-10-02 公開日 2013-12-04 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.801 Å) 主引用文献 Crystal Structures and Functional Characterization of Wild Type and Active Sites Mutants of Cyp101D1. Biochemistry, 52, 2013
4LBT	Endothiapepsin in complex with 100mM acylhydrazone inhibitor 分子名称: (2S)-2-azanyl-3-(3H-indol-3-yl)-N-[(E)-(2,4,6-trimethylphenyl)methylideneamino]propanamide, DIMETHYL SULFOXIDE, Endothiapepsin, ... 著者 Radeva, N, Heine, A, Winquist, J, Klebe, G. 登録日 2013-06-21 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.251 Å) 主引用文献 Structure-based design of inhibitors of the aspartic protease endothiapepsin by exploiting dynamic combinatorial chemistry. Angew.Chem.Int.Ed.Engl., 53, 2014
4H92	Radiation damage study of lysozyme- 0.42 MGy 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C 著者 Sutton, K.A, Snell, E.H. 登録日 2012-09-24 公開日 2013-05-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.2002 Å) 主引用文献 Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies. Acta Crystallogr.,Sect.D, 69, 2013
4H90	Radiation damage study of lysozyme - 0.28 MGy 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C 著者 Sutton, K.A, Snell, E.H. 登録日 2012-09-24 公開日 2013-05-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.1999 Å) 主引用文献 Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies. Acta Crystallogr.,Sect.D, 69, 2013
4H9B	Radiation damage study of lysozyme - 0.70 MGy 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C 著者 Sutton, K.A, Snell, E.H. 登録日 2012-09-24 公開日 2013-05-15 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.1998 Å) 主引用文献 Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies. Acta Crystallogr.,Sect.D, 69, 2013
3RKQ	NKX2.5 Homeodomain dimer bound to ANF-242 DNA 分子名称: ANF-242 DNA, Homeobox protein Nkx-2.5, MAGNESIUM ION 著者 Genis, C, Scone, P, Kasahara, H, Nam, H.-J. 登録日 2011-04-18 公開日 2012-05-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of the human NKX2.5 homeodomain in complex with DNA target. Biochemistry, 51, 2012
4H9H	Radiation damage study of lysozyme - 0.98 MGy 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Lysozyme C 著者 Sutton, K.A. 登録日 2012-09-24 公開日 2013-05-15 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.2002 Å) 主引用文献 Insights into the mechanism of X-ray-induced disulfide-bond cleavage in lysozyme crystals based on EPR, optical absorption and X-ray diffraction studies. Acta Crystallogr.,Sect.D, 69, 2013
4LE1	Crystal structure of the receiver domain of DesR in the inactive state 分子名称: ACETATE ION, GLYCEROL, SULFATE ION, ... 著者 Trajtenberg, F, Larrieux, N, Buschiazzo, A. 登録日 2013-06-25 公開日 2014-07-16 最終更新日 2015-05-06 実験手法 X-RAY DIFFRACTION (1.951 Å) 主引用文献 Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation. MBio, 5, 2014
4LHH	Endothiapepsin in complex with 2mM acylhydrazone inhibitor 分子名称: (2S)-2-azanyl-3-(3H-indol-3-yl)-N-[(E)-(2,4,6-trimethylphenyl)methylideneamino]propanamide, ACETATE ION, DIMETHYL SULFOXIDE, ... 著者 Radeva, N, Heine, A, Klebe, G. 登録日 2013-07-01 公開日 2014-04-02 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Structure-based design of inhibitors of the aspartic protease endothiapepsin by exploiting dynamic combinatorial chemistry. Angew.Chem.Int.Ed.Engl., 53, 2014
4HBN	Crystal structure of the human HCN4 channel C-terminus carrying the S672R mutation 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, PHOSPHATE ION, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 著者 Xu, X, Marni, F, Wu, X, Su, Z, Musayev, F, Shrestha, S, Xie, C, Gao, W, Liu, Q, Zhou, L. 登録日 2012-09-28 公開日 2013-01-16 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Local and Global Interpretations of a Disease-Causing Mutation near the Ligand Entry Path in Hyperpolarization-Activated cAMP-Gated Channel. Structure, 20, 2012
1IWW	Crystal Structure Analysis of Human lysozyme at 152K. 分子名称: CHLORIDE ION, LYSOZYME C 著者 Joti, Y, Nakasako, M, Kidera, A, Go, N. 登録日 2002-06-03 公開日 2002-09-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Nonlinear temperature dependence of the crystal structure of lysozyme: correlation between coordinate shifts and thermal factors. Acta Crystallogr.,Sect.D, 58, 2002

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