5E9K
 
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6XG8
 | | ISCth4 transposase, pre-cleaved complex, PCC | | 分子名称: | DNA (26-MER), Mutator family transposase | | 著者 | Kosek, D, Dyda, F. | | 登録日 | 2020-06-17 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition.
Embo J., 40, 2021
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5DQY
 | | A fully oxidized human thioredoxin | | 分子名称: | BENZOIC ACID, CHLORIDE ION, GLYCEROL, ... | | 著者 | Hwang, J. | | 登録日 | 2015-09-15 | | 公開日 | 2015-12-23 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of fully oxidized human thioredoxin.
Biochem.Biophys.Res.Commun., 467, 2015
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5DTK
 | | Fragments bound to the OXA-48 beta-lactamase: Compound 17 | | 分子名称: | 1,2-ETHANEDIOL, 3,5-di(pyridin-4-yl)benzoic acid, Beta-lactamase, ... | | 著者 | Lund, B.A, Christopeit, T, Leiros, H.-K.S. | | 登録日 | 2015-09-18 | | 公開日 | 2016-05-25 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.60000241 Å) | | 主引用文献 | Screening and Design of Inhibitor Scaffolds for the Antibiotic Resistance Oxacillinase-48 (OXA-48) through Surface Plasmon Resonance Screening.
J.Med.Chem., 59, 2016
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5E9L
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7C7A
 | | Cryo-EM structure of yeast Ribonuclease MRP with substrate ITS1 | | 分子名称: | Internal Transcribed Spacer 1, MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, ... | | 著者 | Lan, P, Wu, J, Lei, M. | | 登録日 | 2020-05-24 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural insight into precursor ribosomal RNA processing by ribonuclease MRP.
Science, 369, 2020
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7CEL
 | | CBH1 (E217Q) IN COMPLEX WITH CELLOHEXAOSE AND CELLOBIOSE | | 分子名称: | 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE I, 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, ... | | 著者 | Divne, C, Stahlberg, J, Jones, T.A. | | 登録日 | 1997-09-24 | | 公開日 | 1997-12-24 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | High-resolution crystal structures reveal how a cellulose chain is bound in the 50 A long tunnel of cellobiohydrolase I from Trichoderma reesei.
J.Mol.Biol., 275, 1998
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5E0L
 | | LC8 - Chica (415-424) Complex | | 分子名称: | Dynein light chain 1, cytoplasmic, Protein Chica peptide, ... | | 著者 | Clark, S.A, Barbar, E.B, Karplus, P.A. | | 登録日 | 2015-09-29 | | 公開日 | 2015-12-30 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | The Anchored Flexibility Model in LC8 Motif Recognition: Insights from the Chica Complex.
Biochemistry, 55, 2016
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6XGW
 | | ISCth4 transposase, pre-reaction complex, PRC | | 分子名称: | DNA (32-MER), Mutator family transposase | | 著者 | Kosek, D, Dyda, F. | | 登録日 | 2020-06-18 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition.
Embo J., 40, 2021
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5E9I
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5E9M
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6XGX
 | | ISCth4 transposase, strand transfer complex 1, STC1 | | 分子名称: | DNA (21-MER), DNA (25-MER), DNA (47-MER), ... | | 著者 | Kosek, D, Dyda, F. | | 登録日 | 2020-06-18 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structures of ISCth4 transpososomes reveal the role of asymmetry in copy-out/paste-in DNA transposition.
Embo J., 40, 2021
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3ECA
 | | CRYSTAL STRUCTURE OF ESCHERICHIA COLI L-ASPARAGINASE, AN ENZYME USED IN CANCER THERAPY (ELSPAR) | | 分子名称: | ASPARTIC ACID, L-asparaginase 2 | | 著者 | Swain, A.L, Jaskolski, M, Housset, D, Rao, J.K.M, Wlodawer, A. | | 登録日 | 1993-07-02 | | 公開日 | 1993-10-31 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal structure of Escherichia coli L-asparaginase, an enzyme used in cancer therapy.
Proc.Natl.Acad.Sci.USA, 90, 1993
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6XF1
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3ENL
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2INE
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6XIP
 | | The 1.5 A Crystal Structure of the Co-factor Complex of NSP7 and the C-terminal Domain of NSP8 from SARS CoV-2 | | 分子名称: | 1,2-ETHANEDIOL, Non-structural protein 7, Non-structural protein 8 | | 著者 | Wilamowski, M, Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-06-20 | | 公開日 | 2020-07-01 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Transient and stabilized complexes of Nsp7, Nsp8, and Nsp12 in SARS-CoV-2 replication.
Biophys.J., 120, 2021
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5EOZ
 | | Mutagenicity of 7-Benzyl guanine lesion and Replication by Human DNA Polymerase beta | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*CP*CP*GP*AP*CP*(GFL)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... | | 著者 | Koag, M.C, Lee, S. | | 登録日 | 2015-11-10 | | 公開日 | 2016-11-23 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.088 Å) | | 主引用文献 | Structural and kinetic studies of the effect of guanine-N7 alkylation and metal cofactors on DNA replication.
Biochemistry, 2018
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2IS7
 | | Crystal Structure of Aldose Reductase complexed with Dichlorophenylacetic acid | | 分子名称: | (2,6-DICHLOROPHENYL)ACETIC ACID, Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Harrison, D.H.T, Milne, A, Brownlee, J.M. | | 登録日 | 2006-10-16 | | 公開日 | 2006-11-21 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and thermodynamic studies of simple aldose reductase-inhibitor complexes.
Bioorg.Chem., 34, 2006
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6XYZ
 | | Crystal structure of the GH18 chitinase ChiB from the chitin utilization locus of Flavobacterium johnsoniae | | 分子名称: | 1,2-ETHANEDIOL, Candidate chitinase Glycoside hydrolase family 18, FORMIC ACID | | 著者 | Mazurkewich, S, Helland, R, MacKenzie, A, Eijsink, V, Pope, P, Branden, G, Larsbrink, J. | | 登録日 | 2020-01-31 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Structural insights of the enzymes from the chitin utilization locus of Flavobacterium johnsoniae.
Sci Rep, 10, 2020
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2DSV
 | | Interactions of protective signalling factor with chitin-like polysaccharide: Crystal structure of the complex between signalling protein from sheep (SPS-40) and a hexasaccharide at 2.5A resolution | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitinase-3-like protein 1, alpha-D-mannopyranose-(1-4)-alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Srivastava, D.B, Ethayathulla, A.S, Kumar, J, Singh, N, Sharma, S, Bhushan, A, Srinivasan, A, Singh, T.P. | | 登録日 | 2006-07-07 | | 公開日 | 2006-08-01 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.54 Å) | | 主引用文献 | Carbohydrate binding properties and carbohydrate induced conformational switch in sheep secretory glycoprotein (SPS-40): crystal structures of four complexes of SPS-40 with chitin-like oligosaccharides
J.Struct.Biol., 158, 2007
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2ZM5
 | | Crystal structure of tRNA modification enzyme MiaA in the complex with tRNA(Phe) | | 分子名称: | MAGNESIUM ION, tRNA delta(2)-isopentenylpyrophosphate transferase, tRNA(Phe) | | 著者 | Sakai, J, Yao, M, Chimnaronk, S, Tanaka, I. | | 登録日 | 2008-04-11 | | 公開日 | 2009-04-14 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Snapshots of dynamics in synthesizing N(6)-isopentenyladenosine at the tRNA anticodon
Biochemistry, 48, 2009
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5ENM
 | | Compound 10 | | 分子名称: | (2~{R},4~{S},6~{S})-4-[2,4-bis(fluoranyl)-5-pyrimidin-5-yl-phenyl]-6-(3,5-dimethyl-1,2-oxazol-4-yl)-1,3-thiazinan-2-amine, Beta-secretase 1, GLYCEROL, ... | | 著者 | Lewis, H.A. | | 登録日 | 2015-11-09 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Targeting the BACE1 Active Site Flap Leads to a Potent Inhibitor That Elicits Robust Brain A beta Reduction in Rodents.
Acs Med.Chem.Lett., 7, 2016
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5ENV
 | | YEAST ALCOHOL DEHYDROGENASE WITH BOUND COENZYME | | 分子名称: | Alcohol dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRIFLUOROETHANOL, ... | | 著者 | Plapp, B.V, Charlier Jr, H.A, Ramaswamy, S. | | 登録日 | 2015-11-09 | | 公開日 | 2015-11-25 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Mechanistic implications from structures of yeast alcohol dehydrogenase complexed with coenzyme and an alcohol.
Arch.Biochem.Biophys., 591, 2015
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7C79
 | | Cryo-EM structure of yeast Ribonuclease MRP | | 分子名称: | MAGNESIUM ION, RNases MRP/P 32.9 kDa subunit, Ribonuclease MRP RNA subunit NME1, ... | | 著者 | Lan, P, Wu, J, Lei, M. | | 登録日 | 2020-05-24 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Structural insight into precursor ribosomal RNA processing by ribonuclease MRP.
Science, 369, 2020
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