8FKC
 
 | |
8FKG
 | |
8FDV
 | |
8FJ7
 | |
8FQJ
 | | LSD1-CoREST in complex with T14, short soaking | | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2S,3R,4R)-2,3,4-trihydroxy-5-[(1R,3S,3aS,13R)-1-hydroxy-10,11-dimethyl-3-{4-[(5-methyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl}-4,6-dioxo-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]pentyl dihydrogen diphosphate | | 著者 | Caroli, J, Mattevi, A. | | 登録日 | 2023-01-06 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
To be published
|
|
8FJ4
 | | LSD1-CoREST in complex with T108, short soaking | | 分子名称: | 3-[(1R,2S)-2-(cyclobutylamino)cyclopropyl]-N-phenylbenzamide, Lysine-specific histone demethylase 1A, REST corepressor 1, ... | | 著者 | Caroli, J, Mattevi, A. | | 登録日 | 2022-12-19 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
to be published
|
|
8FJ6
 | | LSD1-CoREST in complex with T108, long soaking | | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[7,8-dimethyl-2,4-dioxo-5-{3-[3-(phenylcarbamoyl)phenyl]propanoyl}-1,3,4,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate | | 著者 | Caroli, J, Mattevi, A. | | 登録日 | 2022-12-19 | | 公開日 | 2024-06-26 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
to be published
|
|
8FRV
 | | LSD1-CoREST in complex with T17, short soaking | | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[(1R,3S,3aS,13R)-3-[3-(dimethylcarbamoyl)phenyl]-1-hydroxy-10,11-dimethyl-4,6-dioxo-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) | | 著者 | Caroli, J, Mattevi, A. | | 登録日 | 2023-01-09 | | 公開日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
To be published
|
|
8FRQ
 | | LSD1-CoREST in complex with T14, long soaking | | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[(4aS)-7,8-dimethyl-5-(3-{4-[(5-methyl-1,3,4-thiadiazol-2-yl)carbamoyl]phenyl}propanoyl)-2,4-dioxo-3,4,4a,5-tetrahydrobenzo[g]pteridin-10(2H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) | | 著者 | Caroli, J, Mattevi, A. | | 登録日 | 2023-01-08 | | 公開日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
to be published
|
|
8FRI
 | | LSD1-CoREST in complex with AW4, short soaking | | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-2,3,4-trihydroxy-5-[(1R,3S,3aS,13R)-1-hydroxy-10,11-dimethyl-4,6-dioxo-3-([1~1~,2~1~:2~3~,3~1~-terphenyl]-1~4~-yl)-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]pentyl dihydrogen diphosphate (non-preferred name) | | 著者 | Caroli, J, Mattevi, A. | | 登録日 | 2023-01-07 | | 公開日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
To Be Published
|
|
8FSK
 | | LSD1-CoREST in complex with T18, short soaking | | 分子名称: | Lysine-specific histone demethylase 1A, REST corepressor 1, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl (2R,3S,4S)-5-[(1R,3S,3aS,13R)-3-(3-benzamidophenyl)-1-hydroxy-10,11-dimethyl-4,6-dioxo-2,3,5,6-tetrahydro-1H-benzo[g]pyrrolo[2,1-e]pteridin-8(4H)-yl]-2,3,4-trihydroxypentyl dihydrogen diphosphate (non-preferred name) | | 著者 | Caroli, J, Mattevi, A. | | 登録日 | 2023-01-10 | | 公開日 | 2024-08-07 | | 実験手法 | X-RAY DIFFRACTION (3.13 Å) | | 主引用文献 | Distal drug resistance mutations promote covalent inhibitor-adduct Grob fragmentation in LSD1
To Be Published
|
|
8HCU
 | | Crystal structure of BCOR/PCGF1/KDM2B complex | | 分子名称: | ACETIC ACID, BCL-6 corepressor, Polycomb group RING finger protein 1, ... | | 著者 | Shen, F, Chen, R, Xu, J, Liu, J. | | 登録日 | 2022-11-03 | | 公開日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of BCOR/PCGF1/KDM2B complex
to be published
|
|
1E91
 | | Structure of the complex of the Mad1-Sin3B interaction domains | | 分子名称: | MAD PROTEIN (MAX DIMERIZER), PAIRED AMPHIPATHIC HELIX PROTEIN SIN3B | | 著者 | Spronk, C.A.E.M, Tessari, M, Kaan, A.M, Jansen, J.F.A, Vermeulen, M, Stunnenberg, H.G, Vuister, G.W. | | 登録日 | 2000-10-04 | | 公開日 | 2000-11-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The MAD1-Sin3B Interaction Involves a Novel Helical Fold
Nat.Struct.Biol., 7, 2000
|
|
3BRD
 | | CSL (Lag-1) bound to DNA with Lin-12 RAM peptide, P212121 | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*DAP*DAP*DTP*DCP*DTP*DTP*DTP*DCP*DCP*DCP*DAP*DCP*DAP*DGP*DT)-3'), DNA (5'-D(*DTP*DTP*DAP*DCP*DTP*DGP*DTP*DGP*DGP*DGP*DAP*DAP*DAP*DGP*DA)-3'), ... | | 著者 | Wilson, J.J, Kovall, R.A. | | 登録日 | 2007-12-21 | | 公開日 | 2008-04-01 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex.
J.Biol.Chem., 283, 2008
|
|
4O8B
 | | Crystal structure of transcriptional regulator BswR | | 分子名称: | Uncharacterized protein | | 著者 | Ye, F.Z, Wang, C, Kumar, V, Zhang, L.H, Gao, Y.G. | | 登録日 | 2013-12-26 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA rsmZ.
Nucleic Acids Res., 42, 2014
|
|
4R22
 | | TnrA-DNA complex | | 分子名称: | DNA (5'-D(*CP*GP*TP*GP*TP*AP*AP*GP*GP*AP*AP*TP*TP*CP*TP*GP*AP*CP*AP*CP*G)-3'), HTH-type transcriptional regulator TnrA | | 著者 | Schumacher, M.A. | | 登録日 | 2014-08-08 | | 公開日 | 2015-03-04 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
|
|
4R24
 | | Complete dissection of B. subtilis nitrogen homeostatic circuitry | | 分子名称: | DNA (5'-D(*CP*GP*TP*GP*TP*AP*AP*GP*GP*AP*AP*TP*TP*CP*TP*GP*AP*CP*AP*CP*G)-3'), HTH-type transcriptional regulator TnrA | | 著者 | Schumacher, M.A. | | 登録日 | 2014-08-08 | | 公開日 | 2015-03-04 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
|
|
2CKL
 | | Ring1b-Bmi1 E3 catalytic domain structure | | 分子名称: | IODIDE ION, POLYCOMB GROUP RING FINGER PROTEIN 4, UBIQUITIN LIGASE PROTEIN RING2, ... | | 著者 | Buchwald, G, van der Stoop, P, Weichenrieder, O, Perrakis, A, van Lohuizen, M, Sixma, T.K. | | 登録日 | 2006-04-20 | | 公開日 | 2006-05-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and E3-Ligase Activity of the Ring-Ring Complex of Polycomb Proteins Bmi1 and Ring1B.
Embo J., 25, 2006
|
|
4CRV
 | | Complex of human CNOT9 and CNOT1 including two tryptophans | | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, GLYCEROL, ... | | 著者 | Boland, A, Chen, Y, Izaurralde, E, Weichenrieder, O. | | 登録日 | 2014-03-01 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing
Mol.Cell, 54, 2014
|
|
4CRU
 | | Complex of human CNOT9 and CNOT1 including one tryptophan | | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CELL DIFFERENTIATION PROTEIN RCD1 HOMOLOG, GLYCEROL | | 著者 | Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O. | | 登録日 | 2014-03-01 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing
Mol.Cell, 54, 2014
|
|
4CRW
 | | Complex of human DDX6 (RECA-C) and CNOT1 (MIF4G) | | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, GLYCEROL, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | | 著者 | Chen, Y, Boland, A, Izaurralde, E, Weichenrieder, O. | | 登録日 | 2014-03-01 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A Ddx6-Cnot1 Complex and W-Binding Pockets in Cnot9 Reveal Direct Links between Mirna Target Recognition and Silencing
Mol.Cell, 54, 2014
|
|
4DO2
 | |
1YKE
 | |
4ERL
 | |
4ERJ
 | |
