PDB: 97138 件ウェブページステータス検索Chemie searchBIRD

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4ZF6	Cytochrome P450 pentamutant from BM3 with bound PEG 分子名称: 1,2-ETHANEDIOL, Bifunctional P-450/NADPH-P450 reductase, NICKEL (II) ION, ... 著者 Rogers, W.E, Othman, T, Heidary, D.K, Huxford, T. 登録日 2015-04-21 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.773 Å) 主引用文献 Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry, 55, 2016
6A67	Crystal structure of influenza A virus H5 hemagglutinin globular head in complex with the Fab of antibody FLD21.140 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, FLD21.140 Heavy Chain, FLD21.140 Light Chain, ... 著者 Wang, P, Zuo, Y, Sun, J, Zhang, L, Wang, X. 登録日 2018-06-26 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Complementary recognition of the receptor-binding site of highly pathogenic H5N1 influenza viruses by two human neutralizing antibodies. J. Biol. Chem., 293, 2018
2ICW	Crystal structure of a complete ternary complex between TCR, superantigen, and peptide-MHC class II molecule 分子名称: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... 著者 Wang, L, Zhao, Y, Li, H. 登録日 2006-09-13 公開日 2007-03-20 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 Crystal structure of a complete ternary complex of TCR, superantigen and peptide-MHC. Nat.Struct.Mol.Biol., 14, 2007
7R4K	Crystal structure of human mitochondrial NAD kinase 分子名称: MAGNESIUM ION, NAD kinase 2, mitochondrial, ... 著者 Labesse, G, Mary, C, Gelin, M, Lionne, C. 登録日 2022-02-08 公開日 2022-07-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.33 Å) 主引用文献 Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation. Mol.Cell, 82, 2022
7R4J	Crystal structure of human mitochondrial NAD kinase 分子名称: CALCIUM ION, NAD kinase 2, mitochondrial 著者 Labesse, G, Mary, C, Gelin, M, Lionne, C. 登録日 2022-02-08 公開日 2022-07-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation. Mol.Cell, 82, 2022
7R4M	Crystal structure of mitochondrial NAD kinase 分子名称: CALCIUM ION, NAD kinase 2, mitochondrial, ... 著者 Labesse, G, Mary, C, Gelin, M, Lionne, C. 登録日 2022-02-08 公開日 2022-07-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.29 Å) 主引用文献 Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation. Mol.Cell, 82, 2022
4ZF8	Cytochrome P450 pentamutant from BM3 with bound Metyrapone 分子名称: Bifunctional P-450/NADPH-P450 reductase, METYRAPONE, NICKEL (II) ION, ... 著者 Rogers, W.E, Othman, T, Heidary, D.K, Huxford, T. 登録日 2015-04-21 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.766 Å) 主引用文献 Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry, 55, 2016
4JD9	Contact pathway inhibitor from a sand fly 分子名称: 14.5 kDa salivary protein, SULFATE ION 著者 Andersen, J.F, Xu, X, Alvarenga, P. 登録日 2013-02-24 公開日 2013-10-16 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.601 Å) 主引用文献 Novel family of insect salivary inhibitors blocks contact pathway activation by binding to polyphosphate, heparin, and dextran sulfate. Arterioscler Thromb Vasc Biol, 33, 2013
5WII	TraE protein in complex with 2-Chloroisonicotinic Acid 分子名称: 2-chloropyridine-4-carboxylic acid, Conjugal transfer protein 著者 Casu, B, Arya, T, Bessette, B, Baron, C. 登録日 2017-07-19 公開日 2017-11-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.79 Å) 主引用文献 Fragment-based screening identifies novel targets for inhibitors of conjugative transfer of antimicrobial resistance by plasmid pKM101. Sci Rep, 7, 2017
1T2N	Structure of a thermostable triple mutant of Bacillus subtilis lipase obtained through directed evolution 分子名称: Lipase, POTASSIUM ION 著者 Rajakumara, E, Sankaranarayanan, R. 登録日 2004-04-22 公開日 2004-11-23 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural basis of selection and thermostability of laboratory evolved Bacillus subtilis lipase. J.Mol.Biol., 341, 2004
5WIO	TraE protein in complex with 4-(1H-pyrrol-1-yl)pyridine-2-carboxylic acid 分子名称: 4-(1H-pyrrol-1-yl)pyridine-2-carboxylic acid, Conjugal transfer protein 著者 Casu, B, Arya, T, Bessette, B, Baron, C. 登録日 2017-07-19 公開日 2017-11-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Fragment-based screening identifies novel targets for inhibitors of conjugative transfer of antimicrobial resistance by plasmid pKM101. Sci Rep, 7, 2017
5WIC	TraE protein in complex with 2-Furoic Acid (FOA) 分子名称: 2-FUROIC ACID, Conjugal transfer protein 著者 Casu, B, Arya, T, Bessette, B, Baron, C. 登録日 2017-07-19 公開日 2017-11-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Fragment-based screening identifies novel targets for inhibitors of conjugative transfer of antimicrobial resistance by plasmid pKM101. Sci Rep, 7, 2017
5WIP	TraE protein in complex with 2-(2-furyl)isonicotinic acid 分子名称: 2-(furan-2-yl)pyridine-4-carboxylic acid, Conjugal transfer protein 著者 Casu, B, Arya, T, Bessette, B, Baron, C. 登録日 2017-07-19 公開日 2017-11-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Fragment-based screening identifies novel targets for inhibitors of conjugative transfer of antimicrobial resistance by plasmid pKM101. Sci Rep, 7, 2017
3IS9	Crystal structure of the HIV-1 reverse transcriptase (RT) in complex with the alkenyldiarylmethane (ADAM) Non-nucleoside RT Inhibitor dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate). 分子名称: Reverse transcriptase, Reverse transcriptase/ribonuclease H, dimethyl 3,3'-(6-methoxy-6-oxohex-1-ene-1,1-diyl)bis(5-cyano-6-methoxybenzoate) 著者 Ho, W.C, Bauman, J.D, Das, K, Arnold, E. 登録日 2009-08-25 公開日 2010-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystallographic study of a novel subnanomolar inhibitor provides insight on the binding interactions of alkenyldiarylmethanes with human immunodeficiency virus-1 reverse transcriptase. J.Med.Chem., 52, 2009
100D	CRYSTAL STRUCTURE OF THE HIGHLY DISTORTED CHIMERIC DECAMER R(C)D(CGGCGCCG)R(G)-SPERMINE COMPLEX-SPERMINE BINDING TO PHOSPHATE ONLY AND MINOR GROOVE TERTIARY BASE-PAIRING 分子名称: DNA/RNA (5'-R(*CP*)-D(*CP*GP*GP*CP*GP*CP*CP*GP*)-R(*G)-3'), SPERMINE 著者 Ban, C, Ramakrishnan, B, Sundaralingam, M. 登録日 1994-12-05 公開日 1995-03-31 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of the highly distorted chimeric decamer r(C)d(CGGCGCCG)r(G).spermine complex--spermine binding to phosphate only and minor groove tertiary base-pairing. Nucleic Acids Res., 22, 1994
5G40	Crystal structure of adenylate kinase ancestor 4 with Zn and AMP-ADP bound 分子名称: ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ADENYLATE KINSE, ... 著者 Nguyen, V, Kutter, S, English, J, Kern, D. 登録日 2016-05-03 公開日 2016-12-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Evolutionary drivers of thermoadaptation in enzyme catalysis. Science, 355, 2017
1SRM	1H AND 15N ASSIGNMENTS AND SECONDARY STRUCTURE OF THE SRC SH3 DOMAIN 分子名称: SRC TYROSINE KINASE SH3 DOMAIN 著者 Yu, H, Rosen, M.K, Shin, T.B, Seidel-Dugan, C, Brugge, J.S, Schreiber, S.L. 登録日 1994-03-07 公開日 1994-05-31 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 1H and 15N assignments and secondary structure of the Src SH3 domain. FEBS Lett., 324, 1993
4F3Q	Structure of a YebC family protein (CBU_1566) from Coxiella burnetii 分子名称: SULFATE ION, Transcriptional regulatory protein CBU_1566 著者 Franklin, M.C, Cheung, J, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2012-05-09 公開日 2012-06-27 最終更新日 2016-02-10 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
1SRL	1H AND 15N ASSIGNMENTS AND SECONDARY STRUCTURE OF THE SRC SH3 DOMAIN 分子名称: SRC TYROSINE KINASE SH3 DOMAIN 著者 Yu, H, Rosen, M.K, Shin, T.B, Seidel-Dugan, C, Brugge, J.S, Schreiber, S.L. 登録日 1994-03-07 公開日 1994-05-31 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 1H and 15N assignments and secondary structure of the Src SH3 domain. FEBS Lett., 324, 1993
3LEA	Crystal structure of the catalytic domain of TACE with Isoindolinone-biphenyl-hydantoin inhibitor 分子名称: 2-{[(4R)-2,5-dioxo-4-(4-pyridin-3-ylphenyl)imidazolidin-4-yl]methyl}-6-methoxy-1-oxo-1H-isoindolium, Disintegrin and metalloproteinase domain-containing protein 17, ISOPROPYL ALCOHOL, ... 著者 Orth, P. 登録日 2010-01-14 公開日 2010-12-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biaryl substituted hydantoin compounds as TACE inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
4F3R	Structure of phosphopantetheine adenylyltransferase (CBU_0288) from Coxiella burnetii 分子名称: CALCIUM ION, Phosphopantetheine adenylyltransferase 著者 Franklin, M.C, Cheung, J, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2012-05-09 公開日 2012-07-04 最終更新日 2016-02-10 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
6D9X	Discovery of Potent 2-Aryl-6,7-Dihydro-5HPyrrolo[ 1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design 分子名称: 2-phenyl-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole, SODIUM ION, WD repeat-containing protein 5 著者 Phan, J, Fesik, S.W. 登録日 2018-04-30 公開日 2018-09-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo[1,2- a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design. J. Med. Chem., 61, 2018
1AK7	DESTRIN, NMR, 20 STRUCTURES 分子名称: DESTRIN 著者 Hatanaka, H, Moriyama, K, Ogura, K, Ichikawa, S, Yahara, I, Inagaki, F. 登録日 1997-05-29 公開日 1997-10-15 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Tertiary structure of destrin and structural similarity between two actin-regulating protein families. Cell(Cambridge,Mass.), 85, 1996
5G3Z	Crystal structure of adenylate kinase ancestor 3 with Zn, Mg and Ap5A bound 分子名称: ADENYLATE KINSE, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ... 著者 Nguyen, V, Kutter, S, English, J, Kern, D. 登録日 2016-05-03 公開日 2016-12-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Evolutionary drivers of thermoadaptation in enzyme catalysis. Science, 355, 2017
6DAR	Discovery of Potent 2-Aryl-6,7-Dihydro-5HPyrrolo[ 1,2-a]imidazoles as WDR5 WIN-site Inhibitors Using Fragment-Based Methods and Structure-Based Design 分子名称: DIMETHYL SULFOXIDE, N-(cyclopropylmethyl)-N-{[3-(6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-2-yl)phenyl]methyl}-3-methoxybenzamide, SULFATE ION, ... 著者 Phan, J, Fesik, S.W. 登録日 2018-05-01 公開日 2018-09-05 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Discovery of Potent 2-Aryl-6,7-dihydro-5 H-pyrrolo[1,2- a]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design. J. Med. Chem., 61, 2018

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