7R4K

Crystal structure of human mitochondrial NAD kinase

Summary for 7R4K

Entry DOI	10.2210/pdb7r4k/pdb
Descriptor	NAD kinase 2, mitochondrial, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
Functional Keywords	nadp bound form with magnesium, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	45457.03
Authors	Labesse, G.,Mary, C.,Gelin, M.,Lionne, C. (deposition date: 2022-02-08, release date: 2022-07-06, Last modification date: 2024-05-01)
Primary citation	Mary, C.,Soflaee, M.H.,Kesavan, R.,Gelin, M.,Brown, H.,Zacharias, G.,Mathews, T.P.,Lemoff, A.,Lionne, C.,Labesse, G.,Hoxhaj, G. Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation. Mol.Cell, 82:3299-, 2022 Cited by PubMed: 35868311 DOI: 10.1016/j.molcel.2022.06.026 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.33 Å)

Structure validation