7R4K
Crystal structure of human mitochondrial NAD kinase
Summary for 7R4K
Entry DOI | 10.2210/pdb7r4k/pdb |
Descriptor | NAD kinase 2, mitochondrial, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | nadp bound form with magnesium, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 45457.03 |
Authors | Labesse, G.,Mary, C.,Gelin, M.,Lionne, C. (deposition date: 2022-02-08, release date: 2022-07-06, Last modification date: 2024-05-01) |
Primary citation | Mary, C.,Soflaee, M.H.,Kesavan, R.,Gelin, M.,Brown, H.,Zacharias, G.,Mathews, T.P.,Lemoff, A.,Lionne, C.,Labesse, G.,Hoxhaj, G. Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation. Mol.Cell, 82:3299-, 2022 Cited by PubMed: 35868311DOI: 10.1016/j.molcel.2022.06.026 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.33 Å) |
Structure validation
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