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6MIN
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BU of 6min by Molmil
Crystal structure of Taf14 YEATS domain G82A mutant in complex with histone H3K9cr
分子名称: Histone H3K9cr, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Andrews, F.H, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
7TFF
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BU of 7tff by Molmil
Crystal structure of human platelet phosphofructokinase-1 mutant- D564N
分子名称: ATP-dependent 6-phosphofructokinase, platelet type, PHOSPHATE ION, ...
著者Hansen, H, Webb, B.A, Robart, A.R, Narayanasami, S.
登録日2022-01-06
公開日2023-07-12
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Cancer-associated somatic mutations in human phosphofructokinase-1 reveal a critical electrostatic interaction for allosteric regulation of enzyme activity.
Biochem.J., 480, 2023
6V8J
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BU of 6v8j by Molmil
Crystal structure of Ara h 8.0201
分子名称: Ara h 8 allergen isoform, SODIUM ION, SULFATE ION
著者Offermann, L.R, Pote, S, Hurlburt, B.K, McBride, J.K, Chruszcz, M.
登録日2019-12-11
公開日2020-12-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of Ara h 8.0201
To Be Published
6VB0
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HLA-B*15:02 complexed with a synthetic peptide
分子名称: Beta-2-microglobulin, GLYCEROL, MHC class I antigen, ...
著者Schutte, R.J, Li, D, Ostrov, D.A.
登録日2019-12-18
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献HLA-B*15:02 complexed with a synthetic peptide
To Be Published
1C0E
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BU of 1c0e by Molmil
Active Site S19A Mutant of Bovine Heart Phosphotyrosyl Phosphatase
分子名称: PHOSPHATE ION, PROTEIN (TYROSINE PHOSPHATASE (ORTHOPHOSPHORIC MONOESTER PHOSPHOHYDROLASE))
著者Tabernero, L, Evans, B.N, Tishmack, P.A, Van Etten, R.L, Stauffacher, C.V.
登録日1999-07-15
公開日1999-09-28
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The structure of the bovine protein tyrosine phosphatase dimer reveals a potential self-regulation mechanism.
Biochemistry, 38, 1999
6VB5
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HLA-B*15:02 complexed with a synthetic peptide
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ...
著者Schutte, R.J, Li, D, Ostrov, D.A.
登録日2019-12-18
公開日2020-11-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献HLA-B*15:02 complexed with a synthetic peptide
To Be Published
7B4T
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BU of 7b4t by Molmil
Broadly neutralizing DARPin bnD.1 in complex with the HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505)
分子名称: Broadly neutralizing DARPin bnD.1, HIV-1 envelope variable loop 3 crown mimetic peptide V3-IF (BG505), SULFATE ION
著者Friedrich, N, Stiegeler, E, Glogl, M, Lemmin, T, Hansen, S, Kadelka, C, Wu, Y, Ernst, P, Maliqi, L, Foulkes, C, Morin, M, Eroglu, M, Liechti, T, Ivan, B, Reinberg, T, Schaefer, J, Karakus, U, Ursprung, S, Mann, A, Rusert, P, Kouyos, R.D, Robinson, J.A, Gunthard, H.F, Pluckthun, A, Trkola, A.
登録日2020-12-02
公開日2021-11-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization.
Nat Commun, 12, 2021
8FHB
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Protein 32 with aldehyde deformylating oxidase activity from Synechococcus sp.
分子名称: FE (III) ION, tRNA-(MS[2]IO[6]A)-hydroxylase
著者Arenas, R, Wilson, D.K, Mak, W.S, Siegel, J.B.
登録日2022-12-13
公開日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Protein 32 with aldehyde deformylating oxidase activity from Synechococcus sp.
To Be Published
1BNL
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ZINC DEPENDENT DIMERS OBSERVED IN CRYSTALS OF HUMAN ENDOSTATIN
分子名称: COLLAGEN XVIII, ZINC ION
著者Ding, Y.-H, Javaherian, K, Lo, K.-M, Chopra, R, Boehm, T, Lanciotti, J, Harris, B.A, Li, Y, Shapiro, R, Hohenester, E, Timpl, R, Folkman, J, Wiley, D.C.
登録日1998-07-30
公開日1998-10-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Zinc-dependent dimers observed in crystals of human endostatin.
Proc.Natl.Acad.Sci.USA, 95, 1998
5LJM
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BU of 5ljm by Molmil
Structure of SPATA2 PUB domain
分子名称: GLYCEROL, Spermatogenesis-associated protein 2
著者Elliott, P.R, Komander, D.
登録日2016-07-18
公開日2016-08-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.454 Å)
主引用文献SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.
Mol.Cell, 63, 2016
5VKR
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Horse liver alcohol dehydrogenase complexed with adenosine-5-diphosphoribose
分子名称: ADENOSINE-5-DIPHOSPHORIBOSE, Alcohol dehydrogenase E chain, ZINC ION
著者Plapp, B.V, Rubach, J.K, Ramaswamy, S.
登録日2017-04-22
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Horse Liver Alcohol Dehydrogenase: Zinc Coordination and Catalysis.
Biochemistry, 56, 2017
5VL0
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horse liver alcohol dehydrogenase complexed with NADH and N-benzyformamide
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, Alcohol dehydrogenase E chain, ...
著者Plapp, B.V, Brown, E.N, Ramaswamy, S, Baskar Raj, S.
登録日2017-04-24
公開日2017-05-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Horse Liver Alcohol Dehydrogenase: Zinc Coordination and Catalysis.
Biochemistry, 56, 2017
5T98
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Crystal structure of BuGH2Awt
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Glycoside Hydrolase
著者Pluvinage, B, Boraston, A.B.
登録日2016-09-09
公開日2017-09-13
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Molecular basis of an agarose metabolic pathway acquired by a human intestinal symbiont.
Nat Commun, 9, 2018
8Q52
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A PBP-like protein built from fragments of different folds
分子名称: Leucine-specific-binding protein,Chemotaxis protein CheY, SULFATE ION
著者Shanmugaratnam, S, Toledo-Patino, S, Goetz, S.K, Farias-Rico, J.A, Hocker, B.
登録日2023-08-08
公開日2024-04-10
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Molecular handcraft of a well-folded protein chimera.
Febs Lett., 598, 2024
6HY1
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BU of 6hy1 by Molmil
Plasmodium falciparum spermidine synthase in complex with 5'-methylthioadenosine and N,N'-Bis(3-aminopropyl)-1,4-cyclohexanediamine after catalysis in crystal
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, GLYCEROL, ...
著者Sprenger, J, Coertzen, D, Persson, L, Carey, J, Birkholtz, L.M, Louw, B.I.
登録日2018-10-19
公開日2019-10-30
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Plasmodium falciparum spermidine synthase in complex with 5'-methylthioadenosine and N,N'-Bis(3-aminopropyl)-1,4-cyclohexanediamine after catalysis in crystal
To Be Published
6MIO
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BU of 6mio by Molmil
Crystal structure of Taf14 YEATS domain in complex with histone H3K9pr
分子名称: Histone H3K9pr, Transcription initiation factor TFIID subunit 14
著者Klein, B.J, Andrews, F.H, Vann, K.R, Kutateladze, T.G.
登録日2018-09-19
公開日2018-11-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural insights into the pi-pi-pi stacking mechanism and DNA-binding activity of the YEATS domain.
Nat Commun, 9, 2018
6UZP
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HLA-B*15:01 complexed with a synthetic peptide
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Beta-2-microglobulin, ...
著者Schutte, R.J, Li, D, Ostrov, D.A.
登録日2019-11-15
公開日2020-11-18
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献HLA-B*15:01 complexed with a synthetic peptide
To Be Published
8FML
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BU of 8fml by Molmil
Cryo-EM structure of NLR family apoptosis inhibitory protein 5 (NAIP5) in complex with a full-length flagellin (FliC) ligand
分子名称: Baculoviral IAP repeat-containing protein 1e, Flagellin
著者Paidimuddala, B, Zhang, L.
登録日2022-12-23
公開日2024-01-10
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献Structural basis for flagellin-induced NAIP5 activation.
Sci Adv, 9, 2023
8FTA
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Crystal Structure of the second bromodomain of human Polybromo-1 (PB1) in complex with compound 16
分子名称: (2S)-5-chloro-2-(3-methylphenyl)-2,3-dihydroquinazolin-4(1H)-one, Protein polybromo-1, ZINC ION
著者Nunez, R, Smith, B.C.
登録日2023-01-11
公開日2024-01-24
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Crystal Structure of the second bromodomain of human Polybromo-1 (PB1) in complex with compound 16
To Be Published
6V4M
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Trichuris suis BCL-2
分子名称: BCL-2, CHLORIDE ION, SULFATE ION
著者Fairlie, W.D, Lee, E.F, Smith, B.J.
登録日2019-11-28
公開日2020-10-07
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.599 Å)
主引用文献Diversity in the intrinsic apoptosis pathway of nematodes.
Commun Biol, 3, 2020
7WLM
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The Cryo-EM structure of siphonaxanthin chlorophyll a/b type light-harvesting complex II
分子名称: (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CHLOROPHYLL A, ...
著者Seki, S, Nakaniwa, T, Castro-Hartmann, P, Sader, K, Kawamoto, A, Tanaka, H, Qian, P, Kurisu, G, Fujii, R.
登録日2022-01-13
公開日2022-11-23
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural insights into blue-green light utilization by marine green algal light harvesting complex II at 2.78 angstrom.
Bba Adv, 2, 2022
8FVY
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BU of 8fvy by Molmil
40S subunit of the Giardia lamblia 80S ribosome
分子名称: 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S25, ...
著者Eiler, D.R, Wimberly, B.T, Bilodeau, D.Y, Rissland, O.S, Kieft, J.S.
登録日2023-01-20
公開日2024-01-24
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.94 Å)
主引用文献The Giardia lamblia ribosome structure reveals divergence in several biological pathways and the mode of emetine function.
Structure, 32, 2024
6MRV
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Sialidase26 co-crystallized with DANA
分子名称: 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, Sialidase26
著者Zaramela, L.S, Martino, C, Alisson-Silva, F, Rees, S.D, Diaz, S.L, Chuzel, L, Ganatra, M.B, Taron, C.H, Zuniga, C, Chang, G, Varki, A, Zengler, K.
登録日2018-10-15
公開日2019-10-02
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Gut bacteria responding to dietary change encode sialidases that exhibit preference for red meat-associated carbohydrates.
Nat Microbiol, 4, 2019
8FW2
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Cryo-EM structure of full-length human NLRC4 inflammasome with C11 symmetry
分子名称: NLR family CARD domain-containing protein 4
著者Matico, R.E, Yu, X, Miller, R, Somani, S, Ricketts, M.D, Kumar, N, Steele, R.A, Medley, Q, Berger, S, Faustin, B, Sharma, S.
登録日2023-01-20
公開日2024-01-03
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing.
Nat.Struct.Mol.Biol., 31, 2024
5LUS
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Structures of DHBN domain of Pelecanus crispus BLM helicase
分子名称: BLM helicase
著者Shi, J, Chen, W.-F, Zhang, B, Fan, S.-H, Ai, X, Liu, N.-N, Rety, S, Xi, X.-G.
登録日2016-09-09
公開日2017-03-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.433 Å)
主引用文献A helical bundle in the N-terminal domain of the BLM helicase mediates dimer and potentially hexamer formation.
J. Biol. Chem., 292, 2017

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件を2024-08-21に公開中

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