8FML

Cryo-EM structure of NLR family apoptosis inhibitory protein 5 (NAIP5) in complex with a full-length flagellin (FliC) ligand

Summary for 8FML

• Entry DOI: 10.2210/pdb8fml/pdb
• EMDB information: 29296
• Descriptor: Baculoviral IAP repeat-containing protein 1e, Flagellin (2 entities in total)
• Functional Keywords: inflammasome, innate immunity, bacterial ligand, host-pathogen interaction, protein complex, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 2
• Total formula weight: 213742.57

Authors

Paidimuddala, B.,Zhang, L. (deposition date: 2022-12-23, release date: 2024-01-10)

• Primary citation: Paidimuddala, B.,Cao, J.,Zhang, L.; Structural basis for flagellin-induced NAIP5 activation.; Sci Adv, 9:eadi8539-eadi8539, 2023; PubMed: 38055825; DOI: 10.1126/sciadv.adi8539

Experimental method

ELECTRON MICROSCOPY (2.93 Å)