PDB: 47720 件ウェブページステータス検索Chemie searchBIRD

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4ZGX	Structure of aldosterone synthase (CYP11B2) in complex with (+)-(R)-N-(4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide 分子名称: Cytochrome P450 11B2, mitochondrial, N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide, ... 著者 Kuglstatter, A, Joseph, C. 登録日 2015-04-24 公開日 2015-10-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys. J.Med.Chem., 58, 2015
5BTP	Fusobacterium ulcerans ZTP riboswitch bound to ZMP 分子名称: AMINOIMIDAZOLE 4-CARBOXAMIDE RIBONUCLEOTIDE, MAGNESIUM ION, POTASSIUM ION, ... 著者 Jones, C.P, Ferre-D'Amare, A.R. 登録日 2015-06-03 公開日 2015-08-12 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.816 Å) 主引用文献 Recognition of the bacterial alarmone ZMP through long-distance association of two RNA subdomains. Nat.Struct.Mol.Biol., 22, 2015
4FJC	Structure of the SAGA Ubp8/Sgf11(1-72, Delta-ZnF)/Sus1/Sgf73 DUB module 分子名称: GLYCEROL, Protein SUS1, SAGA-associated factor 11, ... 著者 Samara, N.L, Ringel, A.E, Wolberger, C. 登録日 2012-06-11 公開日 2012-07-25 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.826 Å) 主引用文献 A Role for Intersubunit Interactions in Maintaining SAGA Deubiquitinating Module Structure and Activity. Structure, 20, 2012
3CRO	THE PHAGE 434 CRO/OR1 COMPLEX AT 2.5 ANGSTROMS RESOLUTION 分子名称: DNA (5'-D(*AP*AP*GP*TP*AP*CP*AP*AP*AP*CP*TP*TP*TP*CP*TP*TP*G P*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*CP*AP*AP*GP*AP*AP*AP*GP*TP*TP*TP*GP*T P*AP*CP*T)-3'), PROTEIN (434 CRO) 著者 Mondragon, A, Harrison, S.C. 登録日 1990-07-06 公開日 1991-10-15 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 The phage 434 Cro/OR1 complex at 2.5 A resolution. J.Mol.Biol., 219, 1991
3CT5	Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Morphogenesis protein 1 著者 Xiang, Y, Rossmann, M.G. 登録日 2008-04-11 公開日 2008-07-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail. Proc.Natl.Acad.Sci.Usa, 105, 2008
5POF	PanDDA analysis group deposition -- Crystal Structure of BRD1 in complex with N10941a 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, N-(1-benzylpiperidin-4-yl)acetamide, ... 著者 Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F. 登録日 2017-02-07 公開日 2017-03-15 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density. Nat Commun, 8, 2017
4I3A	Structures of PR1 and PR2 intermediates from time-resolved laue crystallography collected at 14ID-B, APS 分子名称: 4'-HYDROXYCINNAMIC ACID, Photoactive yellow protein 著者 Jung, Y.O, Lee, J.H, Kim, J, Schmidt, M, Vukica, S, Moffat, K, Ihee, H. 登録日 2012-11-26 公開日 2013-03-20 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Volume-conserving trans-cis isomerization pathways in photoactive yellow protein visualized by picosecond X-ray crystallography NAT.CHEM., 5, 2013
5APO	Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1 分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, N. 登録日 2015-09-17 公開日 2015-12-16 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.41 Å) 主引用文献 Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation. Cell(Cambridge,Mass.), 164, 2016
2ZKN	X-ray structure of mutant galectin-1/lactose complex 分子名称: Galectin-1, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose 著者 Abe, A, Yoshida, H, Kamitori, S. 登録日 2008-03-26 公開日 2008-09-30 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Functional and structural bases of a cysteine-less mutant as a long-lasting substitute for galectin-1 Glycobiology, 18, 2008
4ZF6	Cytochrome P450 pentamutant from BM3 with bound PEG 分子名称: 1,2-ETHANEDIOL, Bifunctional P-450/NADPH-P450 reductase, NICKEL (II) ION, ... 著者 Rogers, W.E, Othman, T, Heidary, D.K, Huxford, T. 登録日 2015-04-21 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.773 Å) 主引用文献 Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry, 55, 2016
5T9S	Structure of rabbit RyR1 (Ca2+-only dataset, class 4) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-09 公開日 2016-10-12 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
5TB1	Structure of rabbit RyR1 (EGTA-only dataset, class 1) 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-10 公開日 2016-10-12 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
4ZH4	Crystal structure of Escherichia coli RNA polymerase in complex with CBRP18 分子名称: 5-(4-fluorophenyl)-4-[4-fluoro-3-(trifluoromethyl)phenyl]-1H-pyrazole, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Feng, Y, Ebright, R.H. 登録日 2015-04-24 公開日 2015-08-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.993 Å) 主引用文献 Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. Structure, 23, 2015
4FQY	Crystal structure of broadly neutralizing antibody CR9114 bound to H3 influenza hemagglutinin 分子名称: Antibody CR9114 heavy chain, Antibody CR9114 light chain, Hemagglutinin HA1, ... 著者 Ekiert, D.C, Dreyfus, C, Wilson, I.A. 登録日 2012-06-25 公開日 2012-08-22 最終更新日 2018-01-31 実験手法 X-RAY DIFFRACTION (5.253 Å) 主引用文献 Highly conserved protective epitopes on influenza B viruses. Science, 337, 2012
3CSH	Crystal Structure of Glutathione Transferase Pi in complex with the Chlorambucil-Glutathione Conjugate 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Parker, L.J. 登録日 2008-04-09 公開日 2008-07-01 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 The anti-cancer drug chlorambucil as a substrate for the human polymorphic enzyme glutathione transferase P1-1: kinetic properties and crystallographic characterisation of allelic variants. J.Mol.Biol., 380, 2008
3CT1	Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Morphogenesis protein 1 著者 Xiang, Y, Rossmann, M.G. 登録日 2008-04-11 公開日 2008-07-01 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail. Proc.Natl.Acad.Sci.Usa, 105, 2008
5T9M	Structure of rabbit RyR1 (Ca2+-only dataset, class 1) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-09 公開日 2016-10-12 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
5TAY	Structure of rabbit RyR1 (ryanodine dataset, class 2) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-10 公開日 2016-10-12 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
2Z9I	Crystal structure of RV0983 from Mycobacterium tuberculosis- Proteolytically active form 分子名称: GATV, PROBABLE SERINE PROTEASE PEPD, SVEQV 著者 Palaninathan, S.K, Mohamedmohaideen, N.N, Sacchettini, J.C. 登録日 2007-09-20 公開日 2008-06-10 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure and function of the virulence-associated high-temperature requirement A of Mycobacterium tuberculosis Biochemistry, 47, 2008
4Z83	PKAB3 in complex with pyrrolidine inhibitor 47a 分子名称: 7-{(3S,4R)-4-[(5-bromothiophen-2-yl)carbonyl]pyrrolidin-3-yl}quinazolin-4(3H)-one, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha 著者 Lund, B.A, Alam, K.A, Engh, R.A. 登録日 2015-04-08 公開日 2015-12-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of PKA and a PKB Mimic. Chemistry, 22, 2016
4FW2	Crystal structure of RSV three-domain integrase with disordered N-terminal domain 分子名称: Integrase 著者 Shi, K, Aihara, H. 登録日 2012-06-29 公開日 2013-05-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 A possible role for the asymmetric C-terminal domain dimer of Rous sarcoma virus integrase in viral DNA binding. Plos One, 8, 2013
4G7H	Crystal structure of Thermus thermophilus transcription initiation complex 分子名称: 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', DNA-directed RNA polymerase subunit alpha, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2012-07-20 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of transcription initiation. Science, 338, 2012
5T9R	Structure of rabbit RyR1 (Ca2+-only dataset, class 3) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-09 公開日 2016-10-12 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
5TB0	Structure of rabbit RyR1 (EGTA-only dataset, all particles) 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-10 公開日 2016-10-12 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
4I0C	The structure of the camelid antibody cAbHuL5 in complex with human lysozyme 分子名称: CHLORIDE ION, GLYCEROL, Lysozyme C, ... 著者 De Genst, E, Chan, P.H, Pardon, E, Kumita, J.R, Christodoulou, J, Menzer, L, Chirgadze, D.Y, Robinson, C.V, Muyldermans, S, Matagne, A, Wyns, L, Dobson, C.M, Dumoulin, M. 登録日 2012-11-16 公開日 2013-10-09 最終更新日 2013-11-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 A nanobody binding to non-amyloidogenic regions of the protein human lysozyme enhances partial unfolding but inhibits amyloid fibril formation. J.Phys.Chem.B, 117, 2013

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