PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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1AJ7	IMMUNOGLOBULIN 48G7 GERMLINE FAB ANTIBODY COMPLEXED WITH HAPTEN 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID. AFFINITY MATURATION OF AN ESTEROLYTIC ANTIBODY 分子名称: 5-(PARA-NITROPHENYL PHOSPHONATE)-PENTANOIC ACID, IMMUNOGLOBULIN 48G7 FAB (HEAVY CHAIN), IMMUNOGLOBULIN 48G7 FAB (LIGHT CHAIN) 著者 Wedemayer, G.J, Wang, L.H, Patten, P.A, Schultz, P.G, Stevens, R.C. 登録日 1997-05-15 公開日 1997-11-12 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insights into the evolution of an antibody combining site. Science, 276, 1997
5LBV	Structural basis of zika and dengue virus potent antibody cross-neutralization 分子名称: SODIUM ION, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, envelope protein E 著者 Barba-Spaeth, G. 登録日 2016-06-17 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural basis of potent Zika-dengue virus antibody cross-neutralization. Nature, 536, 2016
7X7O	SARS-CoV-2 spike RBD in complex with neutralizing antibody UT28K 分子名称: Spike protein S1, UT28K Fab, heavy chain, ... 著者 Ozawa, T, Tani, H, Anraku, Y, Kita, S, Igarashi, E, Saga, Y, Inasaki, N, Kawasuji, H, Yamada, H, Sasaki, S, Somekawa, M, Sasaki, J, Hayakawa, Y, Yamamoto, Y, Morinaga, Y, Kurosawa, N, Isobe, M, Fukuhara, H, Maenaka, K, Hashiguchi, T, Kishi, H, Kitajima, I, Saito, S, Niimi, H. 登録日 2022-03-10 公開日 2022-05-25 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.75 Å) 主引用文献 Novel super-neutralizing antibody UT28K is capable of protecting against infection from a wide variety of SARS-CoV-2 variants. Mabs, 14, 2022
8C7J	Phage display derived serum albumin binding knob domain engineered within a novel VH framework 3 bispecific antibody format 分子名称: CHLORIDE ION, Fab heavy chain with knob domain, Fab light chain 著者 Adams, R, Macpherson, A. 登録日 2023-01-16 公開日 2023-06-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Serum albumin binding knob domains engineered within a V H framework III bispecific antibody format and as chimeric peptides. Front Immunol, 14, 2023
8C7V	Phage display derived serum albumin binding knob domain engineered within a novel VH framework 3 bispecific antibody format 分子名称: Fab heavy chain, Fab light chain 著者 Adams, R, Macpherson, A. 登録日 2023-01-17 公開日 2023-06-07 実験手法 X-RAY DIFFRACTION (1.61 Å) 主引用文献 Serum albumin binding knob domains engineered within a V H framework III bispecific antibody format and as chimeric peptides. Front Immunol, 14, 2023
7BZ5	Structure of COVID-19 virus spike receptor-binding domain complexed with a neutralizing antibody 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of B38, Light chain of B38, ... 著者 Wu, Y, Qi, J, Gao, F. 登録日 2020-04-26 公開日 2020-05-13 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2. Science, 368, 2020
7YMS	Cryo-EM structure of Coxsackievirus A16 in complex with a neutralizing antibody 9B5 分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... 著者 Cong, Y, Liu, C.X. 登録日 2022-07-29 公開日 2022-08-24 最終更新日 2023-03-15 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Molecular mechanism of antibody neutralization of coxsackievirus A16. Nat Commun, 13, 2022
5O14	Co-crystal structure of a cross-reactive bactericidal human antibody targeting meningococcal vaccine antigen factor H binding protein 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Fab 1A12 Heavy Chain, ... 著者 Lopez-Sagaseta, J. 登録日 2017-05-18 公開日 2018-02-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.195 Å) 主引用文献 Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp. Nat Commun, 9, 2018
5N0A	Crystal structure of A259C covalently linked dengue 2 virus envelope glycoprotein dimer in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 A11 分子名称: BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 HEAVY CHAIN, Envelope Glycoprotein E, ... 著者 Vaney, M.C, Rouvinski, A, Guardado-Calvo, P, Sharma, A, Rey, F.A. 登録日 2017-02-02 公開日 2017-06-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope. Nat Commun, 8, 2017
4HS6	Hepatitus C envelope glycoprotein E2 fragment 412-423 with humanized and affinity-matured antibody MRCT10.v362 分子名称: E2-peptide, MRCT10.v362 Fab heavy chain, MRCT10.v362 Fab light chain 著者 Eigenbrot, C, Ultsch, M. 登録日 2012-10-29 公開日 2013-04-03 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.53 Å) 主引用文献 Glycan shifting on hepatitis C virus (HCV) e2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies. J.Mol.Biol., 425, 2013
4DN3	Crystal structure of anti-mcp-1 antibody cnto888 分子名称: CNTO888 HEAVY CHAIN, CNTO888 LIGHT CHAIN 著者 Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G. 登録日 2012-02-08 公開日 2012-10-03 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888. Mol.Immunol., 51, 2012
2HMI	HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28/DNA COMPLEX 分子名称: DNA (5'-D(*AP*TP*GP*GP*CP*GP*CP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*C)-3'), DNA (5'-D(*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*A)-3'), FAB FRAGMENT OF MONOCLONAL ANTIBODY 28, ... 著者 Ding, J, Arnold, E. 登録日 1998-04-10 公開日 1998-10-14 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution. J.Mol.Biol., 284, 1998
2R1Y	Crystal structure of S25-2 Fab in complex with Kdo analogues 分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-octos-2-ulopyranoside, Fab, antibody fragment (IgG1k), ... 著者 Brooks, C.L, Evans, S.V. 登録日 2007-08-23 公開日 2008-12-30 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes. J.Mol.Biol., 377, 2008
2R23	Crystal structure of S25-2 Fab in complex with Kdo analogues 分子名称: D-glycero-alpha-D-talo-oct-2-ulopyranosonic acid-(2-4)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, Fab, antibody fragment (IgG1k), ... 著者 Brooks, C.L, Evans, S.V. 登録日 2007-08-24 公開日 2008-12-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes. J.Mol.Biol., 377, 2008
2R1W	Crystal structure of S25-2 Fab in complex with Kdo analogues 分子名称: 3,4,5-trideoxy-alpha-D-erythro-oct-3-en-2-ulopyranosonic acid-(2-8)-prop-2-en-1-yl 3-deoxy-alpha-D-manno-oct-2-ulopyranosidonic acid, Fab, antibody fragment (IgG1k), ... 著者 Brooks, C.L, Evans, S.V. 登録日 2007-08-23 公開日 2008-12-30 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Exploration of specificity in germline monoclonal antibody recognition of a range of natural and synthetic epitopes. J.Mol.Biol., 377, 2008
7MLZ	Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody B1-182.1 that targets the receptor-binding domain 分子名称: B1-182.1 Fab heavy chain, B1-182.1 Fab light chain, Spike protein S1, ... 著者 Zhou, T, Tsybovsky, T, Kwong, P.D. 登録日 2021-04-29 公開日 2021-07-28 最終更新日 2021-08-25 実験手法 ELECTRON MICROSCOPY (3.71 Å) 主引用文献 Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants. Science, 373, 2021
2G2R	Green-fluorescent antibody 11G10 in complex with its hapten (nitro-stilbene derivative) 分子名称: Green-fluorescent antibody (11G10)-heavy chain, Green-fluorescent antibody (11G10)-light chain, N-(TRANS-4'-NITRO-4-STILBENYL)-N-METHYL-5-AMINO-PENTANOIC ACID, ... 著者 Debler, E.W, Wilson, I.A. 登録日 2006-02-16 公開日 2006-12-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 The Effects of Antibodies on Stilbene Excited-State Energetics. Angew.Chem.Int.Ed.Engl., 45, 2006
5N09	Crystal structure of L107C/A313C covalently linked dengue 2 virus envelope glycoprotein dimer in complex with the Fab fragment of the broadly neutralizing human antibody EDE2 A11 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 - Heavy chain, BROADLY NEUTRALIZING HUMAN ANTIBODY EDE2 A11 - Light chain, ... 著者 Duquerroy, S, Rouvinski, A, Guardado-Calvo, P, Vaney, M.-C, Sharma, A, Rey, F. 登録日 2017-02-02 公開日 2017-06-07 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Covalently linked dengue virus envelope glycoprotein dimers reduce exposure of the immunodominant fusion loop epitope. Nat Commun, 8, 2017
6ITP	Crystal structure of cortisol complexed with its nanobody at pH 3.5 分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, anti-cortisol camelid antibody 著者 Ding, Y, Ding, L.L, Wang, Z.Y, Zhong, P.Y. 登録日 2018-11-24 公開日 2019-07-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.572 Å) 主引用文献 Structural insights into the mechanism of single domain VHH antibody binding to cortisol. Febs Lett., 593, 2019
6ITQ	Crystal structure of cortisol complexed with its nanobody at pH 10.5 分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, SULFATE ION, anti-cortisol camelid antibody 著者 Ding, Y, Ding, L.L, Wang, Z.Y, Zhong, P.Y. 登録日 2018-11-24 公開日 2019-07-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.526 Å) 主引用文献 Structural insights into the mechanism of single domain VHH antibody binding to cortisol. Febs Lett., 593, 2019
1KNO	CRYSTAL STRUCTURE OF THE COMPLEX OF A CATALYTIC ANTIBODY FAB WITH A TRANSITION STATE ANALOG: STRUCTURAL SIMILARITIES IN ESTERASE-LIKE ABZYMES 分子名称: IGG2A FAB FRAGMENT CNJ206, METHYL-PHOSPHONIC ACID MONO-(4-NITRO-PHENYL) ESTER, ZINC ION 著者 Charbonnier, J.-B, Gigant, B, Knossow, M. 登録日 1995-09-11 公開日 1996-01-29 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of the complex of a catalytic antibody Fab fragment with a transition state analog: structural similarities in esterase-like catalytic antibodies. Proc.Natl.Acad.Sci.USA, 92, 1995
6FYT	Structure of H1 (A/solomon Islands/3/06) Influenza Hemagglutinin in complex with SD38 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 Laursen, N.S, Wilson, I.A. 登録日 2018-03-12 公開日 2018-11-07 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science, 362, 2018
3BD5	Crystal structure of single domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, COBALT (II) ION, catalytic antibody 著者 Park, S.K, Kim, J.S. 登録日 2007-11-14 公開日 2008-04-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of single-domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals Proteins, 71, 2008
3BD4	Crystal structure of single domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, catalytic antibody 著者 Park, S.K, Kim, J.S. 登録日 2007-11-14 公開日 2008-04-01 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal structure of single-domain VL of an anti-DNA binding antibody 3D8 scFv and its active site revealed by complex structures of a small molecule and metals Proteins, 71, 2008
2QQK	Neuropilin-2 a1a2b1b2 Domains in Complex with a Semaphorin-Blocking Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Heavy Chain, Antibody Light Chain, ... 著者 Appleton, B.A, Wiesmann, C. 登録日 2007-07-26 公開日 2007-11-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding Embo J., 26, 2007

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