2MW2
 
 | | Hha-H-NS46 charge zipper complex | | 分子名称: | DNA-binding protein H-NS, Hemolysin expression-modulating protein Hha | | 著者 | Cordeiro, T.N, Garcia, J, Bernado, P, Millet, O, Pons, M. | | 登録日 | 2014-10-24 | | 公開日 | 2015-07-29 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A Three-protein Charge Zipper Stabilizes a Complex Modulating Bacterial Gene Silencing.
J. Biol. Chem., 290, 2015
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1ZYR
 | | Structure of Thermus thermophilus RNA polymerase holoenzyme in complex with the antibiotic streptolydigin | | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase omega chain, ... | | 著者 | Tuske, S, Sarafianos, S.G, Wang, X, Hudson, B, Sineva, E, Mukhopadhyay, J, Birktoft, J.J, Leroy, O, Ismail, S, Clark, A.D, Dharia, C, Napoli, A, Laptenko, O, Lee, J, Borukhov, S, Ebright, R.H, Arnold, E. | | 登録日 | 2005-06-10 | | 公開日 | 2005-09-13 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Inhibition of bacterial RNA polymerase by streptolydigin: stabilization of a straight-bridge-helix active-center conformation.
Cell(Cambridge,Mass.), 122, 2005
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2ZXX
 | | Crystal structure of Cdt1/geminin complex | | 分子名称: | DNA replication factor Cdt1, Geminin | | 著者 | Cho, Y, Lee, C, Hong, B.S, Choi, J.M. | | 登録日 | 2009-01-08 | | 公開日 | 2009-02-17 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for inhibition of the replication licensing factor Cdt1 by geminin
Nature, 430, 2004
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2EHO
 | | Crystal structure of human GINS complex | | 分子名称: | DNA replication complex GINS protein PSF1, DNA replication complex GINS protein PSF2, GINS complex subunit 3, ... | | 著者 | Choi, J.M, Lim, H.S, Kim, J.J, Song, O.K, Cho, Y. | | 登録日 | 2007-03-07 | | 公開日 | 2007-06-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystal structure of the human GINS complex
Genes Dev., 21, 2007
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6U6X
 | | Human SAMHD1 bound to deoxyribo(C*G*C*C*T)-oligonucleotide | | 分子名称: | DNA SC-GS-SC-SC-DT, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, ZINC ION | | 著者 | Taylor, A.B, Bhattacharya, A, Wang, Z, Ivanov, D.N. | | 登録日 | 2019-08-30 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Nucleic acid binding by SAMHD1 contributes to the antiretroviral activity and is enhanced by the GpsN modification.
Nat Commun, 12, 2021
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2LY7
 | | B-flap domain of RNA polymerase (B. subtilis) | | 分子名称: | DNA-directed RNA polymerase subunit beta | | 著者 | Mobli, M. | | 登録日 | 2012-09-12 | | 公開日 | 2014-03-12 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | RNA polymerase-induced remodelling of NusA produces a pause enhancement complex.
Nucleic Acids Res., 43, 2015
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5UNK
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7SIC
 | | Human ATM Dimer | | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine-protein kinase ATM | | 著者 | Warren, C, Pavletich, N.P. | | 登録日 | 2021-10-13 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | | 主引用文献 | Structure of the human ATM kinase and mechanism of Nbs1 binding.
Elife, 11, 2022
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7SID
 | | Human ATM Dimer Bound to Nbs1 | | 分子名称: | MAGNESIUM ION, Nibrin, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Warren, C, Pavletich, N.P. | | 登録日 | 2021-10-13 | | 公開日 | 2022-02-02 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.53 Å) | | 主引用文献 | Structure of the human ATM kinase and mechanism of Nbs1 binding.
Elife, 11, 2022
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2A6E
 | | Crystal structure of the T. Thermophilus RNA polymerase holoenzyme | | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-07-02 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
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2A69
 | | Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic rifapentin | | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-07-02 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
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6DK9
 | | Yeast Ddi2 Cyanamide Hydratase | | 分子名称: | DNA damage-inducible protein, SULFATE ION, ZINC ION | | 著者 | Moore, S.A, Xiao, W, Li, J. | | 登録日 | 2018-05-29 | | 公開日 | 2019-05-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structure of Ddi2, a highly inducible detoxifying metalloenzyme fromSaccharomyces cerevisiae.
J.Biol.Chem., 294, 2019
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2KV6
 | | Tetrapeptide KWKK conjugated to oligonucleotide duplex by a trimethylene tether | | 分子名称: | 5'-D(*GP*CP*TP*AP*GP*CP*GP*AP*GP*TP*CP*C)-3', 5'-D(*GP*GP*AP*CP*TP*CP*GP*CP*TP*AP*GP*C)-3', KWKK Tetrapeptide | | 著者 | Huang, H, Kozekov, I.D, Kozekova, A, Rizzo, C.J, McCullough, A, LLoyd, R.S, Stone, M.P. | | 登録日 | 2010-03-08 | | 公開日 | 2010-07-21 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Minor Groove Orientation of the KWKK Peptide Tethered via the N-Terminal Amine to the Acrolein-Derived 1,N(2)-gamma-Hydroxypropanodeoxyguanosine Lesion with a Trimethylene Linkage .
Biochemistry, 49, 2010
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6EKM
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3LQ9
 | | Crystal structure of human REDD1, a hypoxia-induced regulator of mTOR | | 分子名称: | DNA-damage-inducible transcript 4 protein | | 著者 | Vega-Rubin-de-Celis, S, Abdallah, Z, Brugarolas, J, Zhang, X. | | 登録日 | 2010-02-08 | | 公開日 | 2010-03-09 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural analysis and functional implications of the negative mTORC1 regulator REDD1.
Biochemistry, 49, 2010
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3A4C
 | | Crystal structure of cdt1 C terminal domain | | 分子名称: | DNA replication factor Cdt1 | | 著者 | Cho, Y, Lee, J.H. | | 登録日 | 2009-07-06 | | 公開日 | 2009-10-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.889 Å) | | 主引用文献 | Structure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factors
Protein Sci., 18, 2009
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2MW8
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2KLO
 | | Structure of the Cdt1 C-terminal domain | | 分子名称: | DNA replication factor Cdt1 | | 著者 | Khayrutdinov, B.I, Bae, W.J, Yun, Y.M, Tsuyama, T, Kim, J.J, Hwang, E, Ryu, K.-S, Cheong, H.-K, Cheong, C, Karplus, P.A, Guntert, P, Tada, S, Jeon, Y.H, Cho, Y. | | 登録日 | 2009-07-06 | | 公開日 | 2009-10-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the Cdt1 C-terminal domain: Conservation of the winged helix fold in replication licensing factors
Protein Sci., 18, 2009
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7UKN
 | | Crystal Structure of DDB1 in Complex with the H-Box Motif of pUL145 | | 分子名称: | DNA damage-binding protein 1, H-Box Motif of pUL145 | | 著者 | Wick, E.T, Treadway, C.J, Nicely, N.I, Li, Z, Ren, Z, Baldwin, A.S, Xiong, Y, Harrison, J.S, Brown, N.G. | | 登録日 | 2022-04-01 | | 公開日 | 2022-08-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Insight into Viral Hijacking of CRL4 Ubiquitin Ligase through Structural Analysis of the pUL145-DDB1 Complex.
J.Virol., 96, 2022
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4KA4
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7W68
 | | human single hexameric Mcm2-7 complex | | 分子名称: | DNA replication licensing factor MCM2, DNA replication licensing factor MCM3, DNA replication licensing factor MCM4, ... | | 著者 | Xu, N.N, Lin, Q.P, Liu, C.D, Tian, H.L, Xiang, Y, Zhu, G. | | 登録日 | 2021-12-01 | | 公開日 | 2023-03-08 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | human single hexameric Mcm2-7 complex
To Be Published
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7V9X
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5WCE
 | | Caulobacter crescentus pol III beta | | 分子名称: | DNA polymerase III subunit beta | | 著者 | Oakley, A.J. | | 登録日 | 2017-06-30 | | 公開日 | 2017-07-26 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of Pol III beta from Caulobacter crescentus
To Be Published
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6A1O
 | | Crystal structures of disordered Z-type helices | | 分子名称: | DNA (5'-D(P*CP*A)-3'), DNA (5'-D(P*CP*AP*CP*A)-3'), DNA (5'-D(P*TP*G)-3'), ... | | 著者 | Karthik, S, Mandal, P.K, Thirugnanasambandam, A, Gautham, N. | | 登録日 | 2018-06-07 | | 公開日 | 2019-01-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | | 主引用文献 | Crystal structures of disordered Z-type helices.
Nucleosides Nucleotides Nucleic Acids, 38, 2019
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2CKC
 | | Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction | | 分子名称: | CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7 | | 著者 | Ab, E, de Jong, R.N, Diercks, T, Xiaoyun, J, Daniels, M, Kaptein, R, Folkers, G.E. | | 登録日 | 2006-04-14 | | 公開日 | 2007-05-08 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
To be Published
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