7WZW
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![BU of 7wzw by Molmil](/molmil-images/mine/7wzw) | Cryo-EM structure of MEC1-DDC2-MMS | 分子名称: | DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1 | 著者 | Zhang, Q, Zhang, Q. | 登録日 | 2022-02-19 | 公開日 | 2023-03-01 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structures of Mec1/ATR kinase endogenously stimulated by different genotoxins. Cell Discov, 8, 2022
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7L69
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2KW3
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![BU of 2kw3 by Molmil](/molmil-images/mine/2kw3) | Heterotrimeric interaction between RFX5 and RFXAP | 分子名称: | DNA-binding protein RFX5, Regulatory factor X-associated protein | 著者 | Laird, K.M, Briggs, L.L, Boss, J.M, Summers, M.F, Garvie, C.W. | 登録日 | 2010-03-30 | 公開日 | 2010-08-25 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the heterotrimeric complex between RFX5 and RFXAP
reveals molecular details associated with MHCII gene expression To be Published
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7WZR
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![BU of 7wzr by Molmil](/molmil-images/mine/7wzr) | Cryo-EM structure of Mec1-HU | 分子名称: | DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1 | 著者 | Zhang, Q, Zhang, Q. | 登録日 | 2022-02-19 | 公開日 | 2023-03-08 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structures of Mec1/ATR kinase endogenously stimulated by different genotoxins. Cell Discov, 8, 2022
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4Z5T
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![BU of 4z5t by Molmil](/molmil-images/mine/4z5t) | The nucleosome containing human H3.5 | 分子名称: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Urahama, T, Harada, A, Maehara, K, Horikoshi, N, Sato, K, Sato, Y, Shiraishi, K, Sugino, N, Osakabe, A, Tachiwana, H, Kagawa, W, Kimura, H, Ohkawa, Y, Kurumizaka, H. | 登録日 | 2015-04-03 | 公開日 | 2016-02-10 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis. Epigenetics Chromatin, 9, 2016
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4K4V
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![BU of 4k4v by Molmil](/molmil-images/mine/4k4v) | Poliovirus polymerase elongation complex (r5+1_form) | 分子名称: | DNA/RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-D(P*C)-3'), RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), RNA-directed RNA polymerase 3D-POL, ... | 著者 | Gong, P, Peersen, O.B. | 登録日 | 2013-04-12 | 公開日 | 2013-05-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | 主引用文献 | Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. Plos One, 8, 2013
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7D3V
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3BUA
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![BU of 3bua by Molmil](/molmil-images/mine/3bua) | Crystal Structure of TRF2 TRFH domain and APOLLO peptide complex | 分子名称: | DNA cross-link repair 1B protein, Telomeric repeat-binding factor 2 | 著者 | Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. | 登録日 | 2008-01-02 | 公開日 | 2008-02-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins. Science, 319, 2008
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3NHZ
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![BU of 3nhz by Molmil](/molmil-images/mine/3nhz) | Structure of N-terminal Domain of MtrA | 分子名称: | MAGNESIUM ION, Two component system transcriptional regulator mtrA | 著者 | Barbieri, C.M, Mack, T.R, Robinson, V.L, Miller, M.T, Stock, A.M. | 登録日 | 2010-06-14 | 公開日 | 2010-08-11 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Regulation of response regulator autophosphorylation through interdomain contacts. J.Biol.Chem., 285, 2010
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1ZAY
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1AGO
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1AGZ
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5MLU
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![BU of 5mlu by Molmil](/molmil-images/mine/5mlu) | Crystal structure of the PFV GAG CBS bound to a mononucleosome | 分子名称: | DNA (145-MER), Histone H2A type 1, Histone H2B, ... | 著者 | Pye, V.E, Maskell, D.P, Lesbats, P, Cherepanov, P. | 登録日 | 2016-12-07 | 公開日 | 2017-05-10 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for spumavirus GAG tethering to chromatin. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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332D
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![BU of 332d by Molmil](/molmil-images/mine/332d) | |
5FOS
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![BU of 5fos by Molmil](/molmil-images/mine/5fos) | HUMANISED MONOMERIC RADA IN COMPLEX WITH OLIGOMERISATION PEPTIDE | 分子名称: | DNA REPAIR AND RECOMBINATION PROTEIN RADA, GLYCEROL, PHOSPHATE ION | 著者 | Sharpe, T, Moschetti, T, Fischer, G, Marsh, M, Blundell, T.L, Abell, C, Hyvonen, M. | 登録日 | 2015-11-26 | 公開日 | 2016-10-19 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016
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4MDB
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![BU of 4mdb by Molmil](/molmil-images/mine/4mdb) | Structure of Mos1 transposase catalytic domain and Raltegravir with Mg | 分子名称: | MAGNESIUM ION, Mariner Mos1 transposase, N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamide | 著者 | Richardson, J.M. | 登録日 | 2013-08-22 | 公開日 | 2014-01-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis of Mos1 Transposase Inhibition by the Anti-retroviral Drug Raltegravir. Acs Chem.Biol., 9, 2014
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4MDA
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![BU of 4mda by Molmil](/molmil-images/mine/4mda) | Structure of Mos1 transposase catalytic domain and Raltegravir with Mn | 分子名称: | MANGANESE (II) ION, Mariner Mos1 transposase, N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamide | 著者 | Richardson, J.M. | 登録日 | 2013-08-22 | 公開日 | 2014-01-22 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis of Mos1 Transposase Inhibition by the Anti-retroviral Drug Raltegravir. Acs Chem.Biol., 9, 2014
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1AGK
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1QKL
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![BU of 1qkl by Molmil](/molmil-images/mine/1qkl) | hRPABC14.4, essential subunit of human RNA polymerases I, II and III | 分子名称: | DNA-DIRECTED RNA POLYMERASE II 14.4 KD POLYPEPTIDE | 著者 | Del Rio-Portilla, F, Gaskell, A.G, Gilbert, D, Ladias, J.A.A, Wagner, G. | 登録日 | 1999-07-26 | 公開日 | 1999-11-07 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Hrpabc14.4 Subunit of Human RNA Polymerases Nat.Struct.Biol., 6, 1999
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7Z5I
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7Z5K
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6BCH
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![BU of 6bch by Molmil](/molmil-images/mine/6bch) | I-LtrI E29D bound to cognate substrate (nicked complex) | 分子名称: | DNA (26-MER), DNA (5'-D(*GP*GP*TP*CP*TP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*GP*GP*AP*GP*CP*AP*TP*TP*T)-3'), ... | 著者 | Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. | 登録日 | 2017-10-20 | 公開日 | 2018-10-24 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | I-LtrI E29D bound to cognate substrate (nicked complex) To Be Published
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8PI9
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![BU of 8pi9 by Molmil](/molmil-images/mine/8pi9) | DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -181G>A) | 分子名称: | Chains: E, Chains: F, Hepatocyte nuclear factor 1-alpha | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | 登録日 | 2023-06-21 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024
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8PI7
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![BU of 8pi7 by Molmil](/molmil-images/mine/8pi7) | DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -169C>T) | 分子名称: | CHLORIDE ION, Chains: E, Chains: F, ... | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | 登録日 | 2023-06-21 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024
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8PI8
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![BU of 8pi8 by Molmil](/molmil-images/mine/8pi8) | DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA | 分子名称: | Chains: E, Chains: F, GLYCEROL, ... | 著者 | Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. | 登録日 | 2023-06-21 | 公開日 | 2024-06-19 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024
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