PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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7WZW	Cryo-EM structure of MEC1-DDC2-MMS 分子名称: DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1 著者 Zhang, Q, Zhang, Q. 登録日 2022-02-19 公開日 2023-03-01 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structures of Mec1/ATR kinase endogenously stimulated by different genotoxins. Cell Discov, 8, 2022
7L69	Crystal structure of human polymerase eta complexed with syn N7-benzylguanine 分子名称: DNA (5'-D(*AP*GP*TP*GP*TP*GP*AP*G)-3'), DNA (5'-D(*CP*AP*TP*(7BG)P*CP*TP*CP*AP*CP*AP*CP*T)-3'), DNA polymerase eta 著者 Jung, H, Lee, S. 登録日 2020-12-23 公開日 2022-01-05 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Crystal structure of human polymerase eta complexed with syn N7-benzylguanine To Be Published
2KW3	Heterotrimeric interaction between RFX5 and RFXAP 分子名称: DNA-binding protein RFX5, Regulatory factor X-associated protein 著者 Laird, K.M, Briggs, L.L, Boss, J.M, Summers, M.F, Garvie, C.W. 登録日 2010-03-30 公開日 2010-08-25 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Solution structure of the heterotrimeric complex between RFX5 and RFXAP reveals molecular details associated with MHCII gene expression To be Published
7WZR	Cryo-EM structure of Mec1-HU 分子名称: DNA damage checkpoint protein LCD1, Serine/threonine-protein kinase MEC1 著者 Zhang, Q, Zhang, Q. 登録日 2022-02-19 公開日 2023-03-08 最終更新日 2024-06-26 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structures of Mec1/ATR kinase endogenously stimulated by different genotoxins. Cell Discov, 8, 2022
4Z5T	The nucleosome containing human H3.5 分子名称: DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... 著者 Urahama, T, Harada, A, Maehara, K, Horikoshi, N, Sato, K, Sato, Y, Shiraishi, K, Sugino, N, Osakabe, A, Tachiwana, H, Kagawa, W, Kimura, H, Ohkawa, Y, Kurumizaka, H. 登録日 2015-04-03 公開日 2016-02-10 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis. Epigenetics Chromatin, 9, 2016
4K4V	Poliovirus polymerase elongation complex (r5+1_form) 分子名称: DNA/RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-D(P*C)-3'), RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*UP*CP*GP*UP*CP*GP*AP*AP*A)-3'), RNA-directed RNA polymerase 3D-POL, ... 著者 Gong, P, Peersen, O.B. 登録日 2013-04-12 公開日 2013-05-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Structures of coxsackievirus, rhinovirus, and poliovirus polymerase elongation complexes solved by engineering RNA mediated crystal contacts. Plos One, 8, 2013
7D3V	Non-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3A 分子名称: DNA (5'-D(*AP*TP*TP*TP*TP*CP*AP*AP*TP*T)-3'), DNA dC->dU-editing enzyme APOBEC-3A, ZINC ION 著者 Cao, C.Y, Liu, Y.P, Lan, W.X. 登録日 2020-09-21 公開日 2021-10-06 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Non-specific and specific interactions work cooperatively to promote cytidine deamination catalyzed by APOBEC3 To Be Published
3BUA	Crystal Structure of TRF2 TRFH domain and APOLLO peptide complex 分子名称: DNA cross-link repair 1B protein, Telomeric repeat-binding factor 2 著者 Chen, Y, Yang, Y, van Overbeek, M, Donigian, J.R, Baciu, P, de Lange, T, Lei, M. 登録日 2008-01-02 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A shared docking motif in TRF1 and TRF2 used for differential recruitment of telomeric proteins. Science, 319, 2008
3NHZ	Structure of N-terminal Domain of MtrA 分子名称: MAGNESIUM ION, Two component system transcriptional regulator mtrA 著者 Barbieri, C.M, Mack, T.R, Robinson, V.L, Miller, M.T, Stock, A.M. 登録日 2010-06-14 公開日 2010-08-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Regulation of response regulator autophosphorylation through interdomain contacts. J.Biol.Chem., 285, 2010
1ZAY	PURINE REPRESSOR-HYPOXANTHINE-MODIFIED-PURF-OPERATOR COMPLEX 分子名称: DNA (5'-D(*AP*AP*CP*GP*AP*AP*AP*AP*TP*(1AP)P*TP*TP*TP*TP*CP*GP*T)-3'), HYPOXANTHINE, PROTEIN (PURINE REPRESSOR) 著者 Zheleznova, E.E, Brennan, R.G. 登録日 1998-12-16 公開日 1999-12-16 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The Roles of Exocyclic Groups in the Central Base-Pair Step in Modulating the Affinity of PurR for its Operator To be Published
1AGO	THE SOLUTION NMR STRUCTURE OF AN (S)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE THIRD POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE 分子名称: DNA (5'-D(*CP*GP*GP*AP*CP*AP*YP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3') 著者 Feng, B, Stone, M.P. 登録日 1997-03-25 公開日 1997-08-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Major groove (S)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the S(61,2) and S(61,3) sequence isomers from 1H NMR. Biochemistry, 35, 1996
1AGZ	THE SOLUTION NMR STRUCTURE OF AN (R)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE THIRD POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE 分子名称: DNA (5'-D(*CP*GP*GP*AP*CP*AP*RP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3') 著者 Feng, B, Stone, M.P. 登録日 1997-03-26 公開日 1997-08-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Major groove (R)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the R(61,2) and R(61,3) sequence isomers from 1H NMR. Biochemistry, 34, 1995
5MLU	Crystal structure of the PFV GAG CBS bound to a mononucleosome 分子名称: DNA (145-MER), Histone H2A type 1, Histone H2B, ... 著者 Pye, V.E, Maskell, D.P, Lesbats, P, Cherepanov, P. 登録日 2016-12-07 公開日 2017-05-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis for spumavirus GAG tethering to chromatin. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
332D	CRYSTAL STRUCTURE OF R(GUGUGUA)D(C) WITH TANDEM G-U/U-G WOBBLE PAIRS WITH STRAND SLIPPAGE 分子名称: DNA/RNA (5'-R(*GP*UP*GP*UP*GP*UP*AP*)-D(*C)-3') 著者 Biswas, R, Sundaralingam, M. 登録日 1997-05-14 公開日 1997-09-23 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.58 Å) 主引用文献 Crystal structure of r(GUGUGUA)dC with tandem G x U/U x G wobble pairs with strand slippage. J.Mol.Biol., 270, 1997
5FOS	HUMANISED MONOMERIC RADA IN COMPLEX WITH OLIGOMERISATION PEPTIDE 分子名称: DNA REPAIR AND RECOMBINATION PROTEIN RADA, GLYCEROL, PHOSPHATE ION 著者 Sharpe, T, Moschetti, T, Fischer, G, Marsh, M, Blundell, T.L, Abell, C, Hyvonen, M. 登録日 2015-11-26 公開日 2016-10-19 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016
4MDB	Structure of Mos1 transposase catalytic domain and Raltegravir with Mg 分子名称: MAGNESIUM ION, Mariner Mos1 transposase, N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamide 著者 Richardson, J.M. 登録日 2013-08-22 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Basis of Mos1 Transposase Inhibition by the Anti-retroviral Drug Raltegravir. Acs Chem.Biol., 9, 2014
4MDA	Structure of Mos1 transposase catalytic domain and Raltegravir with Mn 分子名称: MANGANESE (II) ION, Mariner Mos1 transposase, N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(1-methyl-1-{[(5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino}ethyl)-6-oxo-1,6-di hydropyrimidine-4-carboxamide 著者 Richardson, J.M. 登録日 2013-08-22 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Basis of Mos1 Transposase Inhibition by the Anti-retroviral Drug Raltegravir. Acs Chem.Biol., 9, 2014
1AGK	THE SOLUTION NMR STRUCTURE OF AN (R)-A-(N6-ADENYL)-STYRENE OXIDE-RAS61 OLIGODEOXYNUCLEOTIDE MODIFIED AT THE SECOND POSITION OF THE CODON 61 REGION, MINIMIZED AVERAGE STRUCTURE 分子名称: DNA (5'-D(*CP*GP*GP*AP*CP*RP*AP*GP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*CP*TP*TP*GP*TP*CP*CP*G)-3') 著者 Feng, B, Stone, M.P. 登録日 1997-03-25 公開日 1997-08-20 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Major groove (R)-alpha-(N6-adenyl)styrene oxide adducts in an oligodeoxynucleotide containing the human N-ras codon 61 sequence: conformations of the R(61,2) and R(61,3) sequence isomers from 1H NMR. Biochemistry, 34, 1995
1QKL	hRPABC14.4, essential subunit of human RNA polymerases I, II and III 分子名称: DNA-DIRECTED RNA POLYMERASE II 14.4 KD POLYPEPTIDE 著者 Del Rio-Portilla, F, Gaskell, A.G, Gilbert, D, Ladias, J.A.A, Wagner, G. 登録日 1999-07-26 公開日 1999-11-07 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of the Hrpabc14.4 Subunit of Human RNA Polymerases Nat.Struct.Biol., 6, 1999
7Z5I	Transcription factor MYF5 bound to symmetrical site 分子名称: DNA (5'-D(P*AP*CP*GP*CP*GP*TP*CP*AP*GP*CP*TP*GP*AP*CP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*CP*GP*TP*CP*AP*GP*CP*TP*GP*AP*CP*GP*CP*GP*T)-3'), Myogenic factor 5 著者 Morgunova, E, Popov, A, Yin, Y, Taipale, J. 登録日 2022-03-09 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Transcription factor MYF5 bound to symmetrical site To Be Published
7Z5K	Transcription factor MYF5 bound to non-symmetrical site 分子名称: DNA (5'-D(P*AP*CP*GP*CP*GP*TP*CP*AP*GP*CP*TP*GP*TP*TP*GP*CP*GP*C)-3'), DNA (5'-D(P*GP*CP*GP*CP*AP*AP*CP*AP*GP*CP*TP*GP*AP*CP*GP*CP*GP*T)-3'), Myogenic factor 5 著者 Morgunova, E, Popov, A, Yin, Y, Taipale, J. 登録日 2022-03-09 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Transcription factor MYF5 bound to non-symmetrical site To Be Published
6BCH	I-LtrI E29D bound to cognate substrate (nicked complex) 分子名称: DNA (26-MER), DNA (5'-D(*GP*GP*TP*CP*TP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*GP*GP*AP*GP*CP*AP*TP*TP*T)-3'), ... 著者 Brown, C, Zhang, K, McMurrough, T.A, Gloor, G.B, Edgell, D.R, Junop, M. 登録日 2017-10-20 公開日 2018-10-24 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 I-LtrI E29D bound to cognate substrate (nicked complex) To Be Published
8PI9	DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -181G>A) 分子名称: Chains: E, Chains: F, Hepatocyte nuclear factor 1-alpha 著者 Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. 登録日 2023-06-21 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024
8PI7	DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA variant (P2 -169C>T) 分子名称: CHLORIDE ION, Chains: E, Chains: F, ... 著者 Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. 登録日 2023-06-21 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024
8PI8	DNA binding domain of HNF-1A bound to P2-HNF4A promoter DNA 分子名称: Chains: E, Chains: F, GLYCEROL, ... 著者 Kind, L, Myllykoski, M, Raasakka, A, Kursula, P. 登録日 2023-06-21 公開日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular mechanism of HNF-1A-mediated HNF4A gene regulation and promoter-driven HNF4A-MODY diabetes. JCI Insight, 9, 2024

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