7WZW

Cryo-EM structure of MEC1-DDC2-MMS

Summary for 7WZW

Entry DOI	10.2210/pdb7wzw/pdb
EMDB information	32913
Descriptor	Serine/threonine-protein kinase MEC1, DNA damage checkpoint protein LCD1 (2 entities in total)
Functional Keywords	serine/threonine protein kinase, complex, dna damage response, checkpoint control, hydrolase
Biological source	Saccharomyces cerevisiae S288C More
Total number of polymer chains	4
Total formula weight	720428.81
Authors	Zhang, Q.,Zhang, Q. (deposition date: 2022-02-19, release date: 2023-03-01, Last modification date: 2023-03-08)
Primary citation	Zhang, Q.,Wang, P.,Wu, T.,Zhang, Y.,Zheng, Z.,Zhou, S.,Qian, D.,Wang, X.,Cai, G. Structures of Mec1/ATR kinase endogenously stimulated by different genotoxins. Cell Discov, 8:98-98, 2022 Cited by PubMed: 36175395 DOI: 10.1038/s41421-022-00461-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.8 Å)

Structure validation