9BBG
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![BU of 9bbg by Molmil](/molmil-images/mine/9bbg) | Co-crystal structure of human DDB1 bound to fragment UB028671 | 分子名称: | 1,2-ETHANEDIOL, 1H-indol-6-amine, DNA damage-binding protein 1, ... | 著者 | Zeng, H, Dong, A, Frommlet, A, Seitova, A, Loppnau, P, Ackloo, S, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | 登録日 | 2024-04-05 | 公開日 | 2024-06-12 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Co-crystal structure of human DDB1 bound to fragment UB028671 To be published
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9B5C
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8ZNC
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6DU8
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![BU of 6du8 by Molmil](/molmil-images/mine/6du8) | Human Polycsytin 2-l1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystic kidney disease 2-like 1 protein | 著者 | Hulse, R.E, Clapham, D.E, Li, Z, Huang, R.K, Zhang, J. | 登録日 | 2018-06-20 | 公開日 | 2018-07-25 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Cryo-EM structure of the polycystin 2-l1 ion channel. Elife, 7, 2018
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6D66
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![BU of 6d66 by Molmil](/molmil-images/mine/6d66) | Crystal structure of the human dual specificity 1 catalytic domain (C258S) as a maltose binding protein fusion in complex with the designed AR protein mbp3_16 | 分子名称: | 1,2-ETHANEDIOL, D-ALANINE, DI(HYDROXYETHYL)ETHER, ... | 著者 | Gumpena, R, Waugh, D.S, Lountos, G.T. | 登録日 | 2018-04-20 | 公開日 | 2018-09-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.226 Å) | 主引用文献 | MBP-binding DARPins facilitate the crystallization of an MBP fusion protein. Acta Crystallogr F Struct Biol Commun, 74, 2018
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5L9W
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![BU of 5l9w by Molmil](/molmil-images/mine/5l9w) | Crystal structure of the Apc core complex | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, Acetophenone carboxylase alpha subunit, ... | 著者 | Warkentin, E, Weidenweber, S, Ermler, U. | 登録日 | 2016-06-11 | 公開日 | 2017-01-18 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure of the acetophenone carboxylase core complex: prototype of a new class of ATP-dependent carboxylases/hydrolases. Sci Rep, 7, 2017
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6DJU
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![BU of 6dju by Molmil](/molmil-images/mine/6dju) | Mtb ClpB in complex with ATPgammaS and casein, Conformer 1 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chaperone protein ClpB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... | 著者 | Yu, H.J, Li, H.L. | 登録日 | 2018-05-26 | 公開日 | 2018-09-26 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | ATP hydrolysis-coupled peptide translocation mechanism ofMycobacterium tuberculosisClpB. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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7CEL
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![BU of 7cel by Molmil](/molmil-images/mine/7cel) | CBH1 (E217Q) IN COMPLEX WITH CELLOHEXAOSE AND CELLOBIOSE | 分子名称: | 1,4-BETA-D-GLUCAN CELLOBIOHYDROLASE I, 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT (II) ION, ... | 著者 | Divne, C, Stahlberg, J, Jones, T.A. | 登録日 | 1997-09-24 | 公開日 | 1997-12-24 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | High-resolution crystal structures reveal how a cellulose chain is bound in the 50 A long tunnel of cellobiohydrolase I from Trichoderma reesei. J.Mol.Biol., 275, 1998
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6DLB
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6DCV
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6DSV
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![BU of 6dsv by Molmil](/molmil-images/mine/6dsv) | Bst DNA polymerase I post-chemistry (n+2) structure | 分子名称: | DNA (5'-D(*GP*CP*GP*AP*TP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase I, ... | 著者 | Chim, N, Jackson, L.N, Chaput, J.C. | 登録日 | 2018-06-14 | 公開日 | 2018-10-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway. Elife, 7, 2018
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6DGD
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![BU of 6dgd by Molmil](/molmil-images/mine/6dgd) | PriA helicase bound to dsDNA of a DNA replication fork | 分子名称: | DNA (5'-D(P*AP*GP*CP*AP*CP*GP*CP*CP*GP*AP*CP*T)-3'), DNA (5'-D(P*GP*AP*GP*CP*AP*CP*GP*CP*CP*GP*AP*CP*T)-3'), DNA (5'-D(P*GP*TP*CP*GP*GP*CP*GP*TP*GP*CP*TP*C)-3'), ... | 著者 | Satyshur, K.A, Windgassen, T.A, Keck, J.L. | 登録日 | 2018-05-17 | 公開日 | 2018-09-05 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.823 Å) | 主引用文献 | Structure-specific DNA replication-fork recognition directs helicase and replication restart activities of the PriA helicase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5KX7
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![BU of 5kx7 by Molmil](/molmil-images/mine/5kx7) | Irak4-inhibitor co-structure | 分子名称: | Interleukin-1 receptor-associated kinase 4, ~{N}-(3-aminocarbonyl-1-methyl-pyrazol-4-yl)-6-(1-methylpyrazol-4-yl)pyridine-2-carboxamide | 著者 | Fischmann, T.O. | 登録日 | 2016-07-20 | 公開日 | 2016-08-17 | 最終更新日 | 2016-08-24 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Efforts towards the optimization of a bi-aryl class of potent IRAK4 inhibitors. Bioorg.Med.Chem.Lett., 26, 2016
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6DJQ
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![BU of 6djq by Molmil](/molmil-images/mine/6djq) | Vps1 GTPase-BSE fusion complexed with GDP.AlF4- | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, SODIUM ION, ... | 著者 | Varlakhanova, N.V, Brady, T.M, Tornabene, B.A, Hosford, C.J, Chappie, J.S, Ford, M.G.J. | 登録日 | 2018-05-25 | 公開日 | 2018-08-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structures of the fungal dynamin-related protein Vps1 reveal a unique, open helical architecture. J. Cell Biol., 217, 2018
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6DLA
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6DLI
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6D7G
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![BU of 6d7g by Molmil](/molmil-images/mine/6d7g) | Structure of 5F3 TCR in complex with HLA-A2/MART-1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MART1 PEPTIDE-BETA-2-MICROGLOBULIN-HLA-A*02 CHIMERA, T-CELL RECEPTOR GAMMA VARIABLE 8,T-CELL RECEPTOR GAMMA-2 CHAIN C REGION, ... | 著者 | Roy, S, Adams, E.J. | 登録日 | 2018-04-24 | 公開日 | 2019-01-23 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Generation and molecular recognition of melanoma-associated antigen-specific human gamma delta T cells. Sci Immunol, 3, 2018
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5KSC
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![BU of 5ksc by Molmil](/molmil-images/mine/5ksc) | E166A/R274N/R276N Toho-1 Beta-lactamase aztreonam acyl-enzyme intermediate | 分子名称: | 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid, Beta-lactamase Toho-1 | 著者 | Vandavasi, V.G, Langan, P.S, Weiss, K, Parks, J.M, Cooper, J.B, Ginell, S.L, Coates, L. | 登録日 | 2016-07-08 | 公開日 | 2016-11-09 | 最終更新日 | 2019-12-04 | 実験手法 | NEUTRON DIFFRACTION (2.1 Å) | 主引用文献 | Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A beta-Lactamase with a Monobactam Substrate. Antimicrob. Agents Chemother., 61, 2017
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6DGO
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![BU of 6dgo by Molmil](/molmil-images/mine/6dgo) | Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Troglitazone | 分子名称: | (5S)-5-[(4-{[(2R)-6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-yl]methoxy}phenyl)methyl]-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma | 著者 | Shang, J, Kojetin, D.J. | 登録日 | 2018-05-17 | 公開日 | 2019-05-22 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Quantitative structural assessment of graded receptor agonism. Proc.Natl.Acad.Sci.USA, 116, 2019
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5LBD
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![BU of 5lbd by Molmil](/molmil-images/mine/5lbd) | Crystal structure of the N-domain of HMA6, a copper-transporting P-type ATPase | 分子名称: | 1,2-ETHANEDIOL, AMMONIUM ION, CHLORIDE ION, ... | 著者 | Mayerhofer, H, Ravaud, S, Pebay-Peyroula, E. | 登録日 | 2016-06-15 | 公開日 | 2017-08-02 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural Insights into the Nucleotide-Binding Domains of the P1B-type ATPases HMA6 and HMA8 from Arabidopsis thaliana. PLoS ONE, 11, 2016
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5LBM
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![BU of 5lbm by Molmil](/molmil-images/mine/5lbm) | The asymmetric tetrameric structure of the formaldehyde sensing transcriptional repressor FrmR from Escherichia coli | 分子名称: | FORMYL GROUP, Transcriptional repressor FrmR | 著者 | Bisson, C, Baker, P.J, Green, J, Chivers, P.T. | 登録日 | 2016-06-16 | 公開日 | 2016-12-21 | 最終更新日 | 2017-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | The mechanism of a formaldehyde-sensing transcriptional regulator. Sci Rep, 6, 2016
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4UDS
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![BU of 4uds by Molmil](/molmil-images/mine/4uds) | Crystal structure of MbdR regulator from Azoarcus sp. CIB | 分子名称: | MBDR REGULATOR | 著者 | Liu, H, Liu, H.X, MacMahon, S.A, Juarez, J.F, Zamarro, M.T, Eberlein, C, Boll, M, Carmona, M, Diaz, E, Naismith, J.H. | 登録日 | 2014-12-11 | 公開日 | 2014-12-24 | 最終更新日 | 2017-09-13 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Unraveling the Specific Regulation of the Mbd Central Pathway for the Anaerobic Degradation of 3-Methylbenzoate. J.Biol.Chem., 290, 2015
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6DKL
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![BU of 6dkl by Molmil](/molmil-images/mine/6dkl) | Crystal Structure of a Rationally Designed Six-Fold Symmetric DNA Scaffold | 分子名称: | DNA (5'-D(P*CP*AP*CP*AP*CP*CP*GP*TP*AP*C)-3'), DNA (5'-D(P*GP*GP*AP*TP*GP*CP*AP*CP*A)-3'), DNA (5'-D(P*GP*TP*AP*CP*GP*GP*AP*TP*CP*CP*AP*G)-3'), ... | 著者 | Simmons, C.R, Zhang, F, Yan, H. | 登録日 | 2018-05-29 | 公開日 | 2018-08-29 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (3.034 Å) | 主引用文献 | Self-Assembly of a 3D DNA Crystal Structure with Rationally Designed Six-Fold Symmetry. Angew. Chem. Int. Ed. Engl., 57, 2018
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6DBU
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![BU of 6dbu by Molmil](/molmil-images/mine/6dbu) | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | 分子名称: | CALCIUM ION, Forward strand RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | 登録日 | 2018-05-03 | 公開日 | 2018-08-01 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | DNA melting initiates the RAG catalytic pathway. Nat. Struct. Mol. Biol., 25, 2018
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6DCU
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