4J6K
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3P2X
| Insulin fibrillation is the Janus face of induced fit. A chiaral clamp stabilizes the native state at the expense of activity | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | 著者 | Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2010-10-04 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity To be Published
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4BP2
| CRYSTALLOGRAPHIC REFINEMENT OF BOVINE PRO-PHOSPHOLIPASE A2 AT 1.6 ANGSTROMS RESOLUTION | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, PHOSPHOLIPASE A2 | 著者 | Finzel, B.C, Weber, P.C, Ohlendorf, D.H, Salemme, F.R. | 登録日 | 1990-09-07 | 公開日 | 1991-10-15 | 最終更新日 | 2017-11-29 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystallographic refinement of bovine pro-phospholipase A2 at 1.6 A resolution. Acta Crystallogr.,Sect.B, 47, 1991
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4GCC
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3P33
| Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity | 分子名称: | CHLORIDE ION, Insulin, PHENOL, ... | 著者 | Hua, Q.X, Wan, Z.L, Huang, K, Hu, S.Q, Phillip, N.F, Jia, W.H, Whittingham, J, Dodson, G.G, Katsoyannis, P.G, Weiss, M.A. | 登録日 | 2010-10-04 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity To be Published
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4GDJ
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4J9E
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3P64
| Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme | 分子名称: | CHLORIDE ION, GOLD 3+ ION, GOLD ION, ... | 著者 | Wei, H, Wang, Z, Zhang, J, House, S, Gao, Y.-G, Yang, L, Robinson, H, Tan, L.H, Xing, H, Hou, C, Robertson, I.M, Zuo, J.-M, Lu, Y. | 登録日 | 2010-10-11 | 公開日 | 2011-02-09 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme. Nat Nanotechnol, 6, 2011
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3P6E
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3P6O
| Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC1-Etg-Dans | 分子名称: | (3S,5S,7S)-N-(2-{2-[2-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)ethoxy]ethoxy}ethyl)tricyclo[3.3.1.1~3,7~]decane-1-carboxamide, Camphor 5-monooxygenase, POTASSIUM ION, ... | 著者 | Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B. | 登録日 | 2010-10-11 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC1-Etg-Dans To be Published
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4GCF
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2XN6
| Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein | 分子名称: | 1,2-ETHANEDIOL, 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-6-CARBOXYLIC ACID, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... | 著者 | Qi, X, Yan, Y, Wei, Z, Zhou, A. | 登録日 | 2010-07-30 | 公開日 | 2011-02-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins. J.Biol.Chem., 286, 2011
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2XN7
| Crystal structure of thyroxine-binding globulin complexed with thyroxine-fluoresein (T405-CF) | 分子名称: | 1,2-ETHANEDIOL, 3',6'-DIHYDROXY-3-OXO-3H-SPIRO[2-BENZOFURAN-1,9'-XANTHENE]-5-CARBOXYLIC ACID, 3,5,3',5'-TETRAIODO-L-THYRONINE, ... | 著者 | Qi, X, Yan, Y, Wei, Z, Zhou, A. | 登録日 | 2010-07-30 | 公開日 | 2011-02-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | Allosteric Modulation of Hormone Release from Thyroxine and Corticosteroid Binding-Globulins. J.Biol.Chem., 286, 2011
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1I1Z
| MUTANT HUMAN LYSOZYME (Q86D) | 分子名称: | LYSOZYME C | 著者 | Kuroki, R. | 登録日 | 2001-02-05 | 公開日 | 2001-02-28 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and thermodynamic responses of mutations at a Ca2+ binding site engineered into human lysozyme. J.Biol.Chem., 273, 1998
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4JDU
| The crystal structure of an aerotolerance-related membrane protein from Bacteroides fragilis NCTC 9343 with multiple mutations to serines. | 分子名称: | Aerotolerance-related membrane protein, CALCIUM ION, FORMIC ACID | 著者 | Fan, Y, Tan, K, Bigelow, L, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2013-02-25 | 公開日 | 2013-03-27 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | The crystal structure of an aerotolerance-related membrane protein from Bacteroides fragilis NCTC 9343 with multiple mutations to serines. To be Published
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3P99
| Sterol 14alpha-demethylase (CYP51) from Trypanosoma brucei in complex with delta7-14alpha-methylene-cyclopropyl-dihydrolanosterol | 分子名称: | (3alpha,9beta,10alpha,13alpha)-30-cyclopropylidenelanost-7-en-3-ol, PROTOPORPHYRIN IX CONTAINING FE, Sterol 14-alpha-demethylase | 著者 | Lepesheva, G.I, Hargrove, T.Y, Waterman, M.R, Wawrzak, Z. | 登録日 | 2010-10-16 | 公開日 | 2011-11-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural complex of sterol 14alpha-demethylase (CYP51) with 14alpha-methylenecyclopropyl-delta7-24, 25-dihydrolanosterol J.Lipid Res., 53, 2012
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4GJA
| Crystal structure of renin in complex with NVP-AYL747 (compound 5) | 分子名称: | (3S,5R)-N-(2,2-diphenylethyl)-5-{[(4-methylphenyl)sulfonyl]amino}piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, ... | 著者 | Ostermann, N, Zink, F, Kroemer, M. | 登録日 | 2012-08-09 | 公開日 | 2013-02-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore. J.Med.Chem., 56, 2013
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7Y4N
| Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos | 分子名称: | Growth factor receptor-bound protein 2 | 著者 | Pooppadi, M.S, Ikeya, T, Sugasawa, H, Watanabe, R, Mishima, M, Inomata, K, Ito, Y. | 登録日 | 2022-06-15 | 公開日 | 2022-08-31 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos. Biochem.Biophys.Res.Commun., 625, 2022
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4GJC
| Crystal structure of renin in complex with NVP-BCH965 (compound 9) | 分子名称: | (3S,5R)-5-{[(4-methylphenyl)sulfonyl]amino}-N-(9H-xanthen-9-ylmethyl)piperidine-3-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, Renin, ... | 著者 | Ostermann, N, Zink, F, Kroemer, M. | 登録日 | 2012-08-09 | 公開日 | 2013-02-13 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A novel class of oral direct Renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophore. J.Med.Chem., 56, 2013
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4JOO
| Spirocyclic Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors | 分子名称: | (4R)-2'-amino-6-bromo-1',2,2-trimethyl-2,3-dihydrospiro[chromene-4,4'-imidazol]-5'(1'H)-one, Beta-secretase 1, NICKEL (II) ION | 著者 | Vigers, G.P.A, Smith, D. | 登録日 | 2013-03-18 | 公開日 | 2013-04-10 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Spirocyclic beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitors: from hit to lowering of cerebrospinal fluid (CSF) amyloid beta in a higher species. J.Med.Chem., 56, 2013
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4GJX
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3OXW
| Crystal Structure of HIV-1 I50V, A71V Protease in Complex with the Protease Inhibitor Darunavir | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, 1,2-ETHANEDIOL, ACETATE ION, ... | 著者 | Mittal, S, Bandaranayake, R.M, Schiffer, C.A. | 登録日 | 2010-09-22 | 公開日 | 2011-09-28 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and thermodynamic basis of amprenavir/darunavir and atazanavir resistance in HIV-1 protease with mutations at residue 50. J.Virol., 87, 2013
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3OVO
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4B1A
| Crystal structure of lysozyme with Keggin molecule | 分子名称: | CHLORIDE ION, LYSOZYME C, Phosphomolybdate keggin, ... | 著者 | Mukhopadhyay, A, Silva, T.S, Romao, M.J, Romao, C.C. | 登録日 | 2012-07-09 | 公開日 | 2013-02-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | 主引用文献 | Characterization of a Versatile Organometallic Pro-Drug (Corm) for Experimental Co Based Therapeutics. Dalton Trans, 42, 2013
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3OYO
| Crystal structure of hemopexin fold protein CP4 from cow pea | 分子名称: | CALCIUM ION, CHLORIDE ION, SODIUM ION, ... | 著者 | Gaur, V, Chanana, V, Salunke, D.M. | 登録日 | 2010-09-23 | 公開日 | 2011-02-09 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The structure of a haemopexin-fold protein from cow pea (Vigna unguiculata) suggests functional diversity of haemopexins in plants Acta Crystallogr.,Sect.F, 67, 2011
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