4GCC
Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 1
Summary for 4GCC
Entry DOI | 10.2210/pdb4gcc/pdb |
Related | 4DD0 4DD1 4DD2 4DD3 4DD4 4DD6 4DD7 4DD9 4DDA 4DDB 4DDC 4G49 4G4A 4G4B 4G4C 4G4H 4GCB 4GCD 4GCE 4GCF 4GCJ |
Descriptor | Lysozyme C, DIMETHYL SULFOXIDE, Cisplatin, ... (4 entities in total) |
Functional Keywords | cisplatin, carboplatin, histidine, relative toxicity, binding occupancy, x-ray radiation damage, radiation therapy, temperature variation and structure, hydrolase |
Biological source | Gallus gallus (chicken) |
Cellular location | Secreted: P00698 |
Total number of polymer chains | 1 |
Total formula weight | 15243.78 |
Authors | Helliwell, J.R.,Tanley, S.W.M. (deposition date: 2012-07-30, release date: 2013-01-02, Last modification date: 2023-09-13) |
Primary citation | Helliwell, J.R.,Tanley, S.W. The crystal structure analysis of the relative binding of cisplatin and carboplatin in a mixture with histidine in a protein studied at 100 and 300 K with repeated X-ray irradiation. Acta Crystallogr.,Sect.D, 69:121-125, 2013 Cited by PubMed: 23275170DOI: 10.1107/S090744491204423X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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