4G4H
100K X-ray diffraction study of carboplatin binding to HEWL in DMSO media after 13 months of crystal storage
Summary for 4G4H
Entry DOI | 10.2210/pdb4g4h/pdb |
Related | 4DD0 4DD1 4DD2 4DD3 4DD4 4DD6 4DD7 4DD9 4DDA 4DDB 4DDC 4G49 4G4A 4G4B 4G4C |
Descriptor | Lysozyme C, DIMETHYL SULFOXIDE, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | cisplatin, carboplatin, aqueous media, dmso media, omega scan data collection, capillaries, hydrolase |
Biological source | Gallus gallus (chicken) |
Cellular location | Secreted: P00698 |
Total number of polymer chains | 1 |
Total formula weight | 15336.28 |
Authors | Tanley, S.W.M.,Schreurs, A.M.M.,Kroon-Batenburg, L.M.J.,Helliwell, J.R. (deposition date: 2012-07-16, release date: 2012-11-07, Last modification date: 2023-09-13) |
Primary citation | Tanley, S.W.,Schreurs, A.M.,Kroon-Batenburg, L.M.,Helliwell, J.R. Room-temperature X-ray diffraction studies of cisplatin and carboplatin binding to His15 of HEWL after prolonged chemical exposure. Acta Crystallogr.,Sect.F, 68:1300-1306, 2012 Cited by PubMed: 23143236DOI: 10.1107/S1744309112042005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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