4G49

Room temperature X-ray diffraction of cisplatin binding to HEWL in aqueous media after 15 months of crystal storage

Summary for 4G49
Related4DD0 4DD1 4DD2 4DD3 4DD4 4DD6 4DD7 4DD9 4DDA 4DDB 4DDC 4G4A 4G4B 4G4C 4G4H
DescriptorLysozyme C, CHLORIDE ION, ACETATE ION, ... (5 entities in total)
Functional Keywordscisplatin, carboplatin, aqueous media, dmso media, omega scan data collection, capillaries, hydrolase
Biological sourceGallus gallus (chicken)
Cellular locationSecreted: P00698
Total number of polymer chains1
Total formula weight15120.24
Authors
Tanley, S.W.M.,Schreurs, A.M.M.,Kroon-Batenburg, L.M.J.,Helliwell, J.R. (deposition date: 2012-07-16, release date: 2012-11-07, Last modification date: 2013-01-23)
Primary citationHelliwell, J.R.,Kroon-Batenburg, L.M.,Schreurs, A.M.,Tanley, S.W.
Room-temperature X-ray diffraction studies of cisplatin and carboplatin binding to His15 of HEWL after prolonged chemical exposure.
Acta Crystallogr.,Sect.F, 68:1300-1306, 2012
PubMed: 23143236
DOI: 110.1107/S1744309112042005
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation
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178938

PDB entries from 2021-06-16