PDB: 97922 件ウェブページステータス検索Chemie searchBIRD

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1Q8X	NMR structure of human cofilin 分子名称: Cofilin, non-muscle isoform 著者 Pope, B.J, Zierler-Gould, K.M, Kuhne, R, Weeds, A.G, Ball, L.J. 登録日 2003-08-22 公開日 2004-07-06 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The solution structure of human cofilin: rationalizing actin binding and pH sensitivity J.Biol.Chem., 279, 2004
8RTT	Structure of the formin Cdc12 bound to the barbed end of phalloidin-stabilized F-actin. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, cytoplasmic 1, ... 著者 Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. 登録日 2024-01-29 公開日 2024-04-10 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.56 Å) 主引用文献 Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
8S9V	CRISPR-Cas type III-D effector complex bound to a self-target RNA in the pre-cleavage state 分子名称: CRISPR RNA, Cas10, Cas7-2x, ... 著者 Schwartz, E.A, Taylor, D.W. 登録日 2023-03-30 公開日 2024-04-24 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 RNA targeting and cleavage by the type III-Dv CRISPR effector complex. Nat Commun, 15, 2024
8S9X	CRISPR-Cas type III-D effector complex bound to self-target RNA in a post-cleavage state 分子名称: CRISPR RNA, Cas10, Cas7-2x, ... 著者 Schwartz, E.A, Taylor, D.W. 登録日 2023-03-30 公開日 2024-04-24 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.44 Å) 主引用文献 RNA targeting and cleavage by the type III-Dv CRISPR effector complex. Nat Commun, 15, 2024
8S9T	CRISPR-Cas type III-D effector complex 分子名称: CRISPR RNA, Cas10, Cas7-2x, ... 著者 Schwartz, E.A, Taylor, D.W. 登録日 2023-03-30 公開日 2024-04-24 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.52 Å) 主引用文献 RNA targeting and cleavage by the type III-Dv CRISPR effector complex. Nat Commun, 15, 2024
8RU0	Structure of the undecorated barbed end of F-actin. 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... 著者 Oosterheert, W, Boiero Sanders, M, Funk, J, Prumbaum, D, Raunser, S, Bieling, P. 登録日 2024-01-29 公開日 2024-04-10 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.08 Å) 主引用文献 Molecular mechanism of actin filament elongation by formins. Science, 384, 2024
1A0U	HEMOGLOBIN (VAL BETA1 MET) MUTANT 分子名称: HEMOGLOBIN (ALPHA CHAIN), HEMOGLOBIN (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE 著者 Kavanaugh, J.S, Arnone, A. 登録日 1997-12-08 公開日 1998-03-18 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 High-resolution crystal structures of human hemoglobin with mutations at tryptophan 37beta: structural basis for a high-affinity T-state,. Biochemistry, 37, 1998
1H9H	COMPLEX OF EETI-II WITH PORCINE TRYPSIN 分子名称: CALCIUM ION, TRYPSIN, TRYPSIN INHIBITOR II 著者 Kraetzner, R, Wentzel, A, Kolmar, H, Uson, I. 登録日 2001-03-12 公開日 2004-07-26 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of Ecballium Elaterium Trypsin Inhibitor II (Eeti-II): A Rigid Molecular Scaffold Acta Crystallogr.,Sect.D, 61, 2005
7PXY	Crystal structure of Arabidopsis thaliana 5-enol-pyruvyl-shikimate-3-phosphate synthase (EPSPS) in open conformation 分子名称: 3-phosphoshikimate 1-carboxyvinyltransferase, chloroplastic, CHLORIDE ION, ... 著者 Ruszkowski, M. 登録日 2021-10-08 公開日 2022-04-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Deciphering the structure of Arabidopsis thaliana 5- enol -pyruvyl-shikimate-3-phosphate synthase: An essential step toward the discovery of novel inhibitors to supersede glyphosate. Comput Struct Biotechnol J, 20, 2022
7PRR	Structure of the ligand binding domain of the PctD (PA4633) chemoreceptor of Pseudomonas aeruginosa PAO1 in complex with acetylcholine 分子名称: ACETYLCHOLINE, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Gavira, J.A, Matilla, M.A, Martin-Mora, D, Krell, T. 登録日 2021-09-22 公開日 2022-05-11 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Chemotaxis of the Human Pathogen Pseudomonas aeruginosa to the Neurotransmitter Acetylcholine. Mbio, 13, 2022
1QNT	X-ray structure of human O6alkylguanine-DNA alkyltransferase 分子名称: METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE 著者 Wibley, J.E.A, Moody, P.C.E. 登録日 1999-10-20 公開日 1999-12-16 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of the Human O(6)-Alkylguanine-DNA Alkyltransferase. Nucleic Acids Res., 28, 2000
7PRQ	Structure of the ligand binding domain of the PctD (PA4633) chemoreceptor of Pseudomonas aeruginosa PAO1 in complex with choline. 分子名称: 1,2-ETHANEDIOL, CHOLINE ION, GLYCEROL, ... 著者 Gavira, J.A, Matilla, M.A, Martin-Mora, D, Krell, T. 登録日 2021-09-22 公開日 2022-05-11 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Chemotaxis of the Human Pathogen Pseudomonas aeruginosa to the Neurotransmitter Acetylcholine. Mbio, 13, 2022
7PQO	Catalytic fragment of MASP-1 in complex with P1 site mutant ecotin 分子名称: Ecotin, GLYCEROL, Mannan-binding lectin serine protease 1, ... 著者 Harmat, V, Fodor, K, Heja, D. 登録日 2021-09-17 公開日 2022-05-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.39 Å) 主引用文献 Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation. J.Biol.Chem., 298, 2022
7PSG	Structure of the ligand binding domain of the PacA (ECA2226) chemoreceptor of Pectobacterium atrosepticum SCRI1043 in complex with betaine. 分子名称: GLYCEROL, Methyl-accepting chemotaxis protein, TRIMETHYL GLYCINE 著者 Gavira, J.A, Matilla, M.A, Velando, F, Krell, T. 登録日 2021-09-23 公開日 2022-05-11 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Chemotaxis of the Human Pathogen Pseudomonas aeruginosa to the Neurotransmitter Acetylcholine. Mbio, 13, 2022
8SKT	Structure of ternary complex of mouse cGAS with dsDNA and bound ATP with 5 mM Mn2+ 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic GMP-AMP synthase, MANGANESE (II) ION, ... 著者 Wu, S, Sohn, J. 登録日 2023-04-20 公開日 2024-04-24 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 The structural basis for 2'-5'/3'-5'-cGAMP synthesis by cGAS. Nat Commun, 15, 2024
7PQN	Catalytic fragment of MASP-2 in complex with ecotin 分子名称: Ecotin, GLYCEROL, Mannan-binding lectin serine protease 2 A chain, ... 著者 Harmat, V, Fodor, K, Heja, D. 登録日 2021-09-17 公開日 2022-05-18 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.400015 Å) 主引用文献 Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation. J.Biol.Chem., 298, 2022
8EMB	X-ray crystal structure of Thermosynechococcus elongatus Si3 domain of RNA polymerase RpoC2 subunit 分子名称: DNA-directed RNA polymerase subunit beta' 著者 Murakami, K.S, Imashimizu, M, Qayyum, M.Z, Vishwakarma, R.K, Yuzenkova, Y. 登録日 2022-09-27 公開日 2022-11-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Structure and function of the Si3 insertion integrated into the trigger loop/helix of cyanobacterial RNA polymerase. Proc.Natl.Acad.Sci.USA, 121, 2024
1A00	HEMOGLOBIN (VAL BETA1 MET, TRP BETA37 TYR) MUTANT 分子名称: HEMOGLOBIN (ALPHA CHAIN), HEMOGLOBIN (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE 著者 Kavanaugh, J.S, Arnone, A. 登録日 1997-12-08 公開日 1998-03-18 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 High-resolution crystal structures of human hemoglobin with mutations at tryptophan 37beta: structural basis for a high-affinity T-state,. Biochemistry, 37, 1998
1A0Z	HEMOGLOBIN (VAL BETA1 MET) MUTANT 分子名称: HEMOGLOBIN (ALPHA CHAIN), HEMOGLOBIN (BETA CHAIN), PROTOPORPHYRIN IX CONTAINING FE 著者 Kavanaugh, J.S, Arnone, A. 登録日 1997-12-08 公開日 1998-03-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 High-resolution crystal structures of human hemoglobin with mutations at tryptophan 37beta: structural basis for a high-affinity T-state,. Biochemistry, 37, 1998
1IM6	CRYSTAL STRUCTURE OF UNLIGATED HPPK(R82A) FROM E.COLI AT 1.74 ANGSTROM RESOLUTION 分子名称: 6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE, CHLORIDE ION 著者 Blaszczyk, J, Ji, X. 登録日 2001-05-09 公開日 2003-04-15 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Dynamic Roles of Arginine Residues 82 and 92 of Escherichia coli 6-Hydroxymethyl-7,8-dihydropterin Pyrophosphokinase: Crystallographic Studies Biochemistry, 42, 2003
7PIE	Protein kinase A catalytic subunit in complex with PKI5-24 and EN068 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-azanyl-5-[3-[(2R)-morpholin-2-yl]phenyl]benzenecarbonitrile, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Glinca, S, Mueller, J.M, Ruf, M, Merkl, S. 登録日 2021-08-19 公開日 2022-09-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.427 Å) 主引用文献 Magnet for the Needle in Haystack: "Crystal Structure First" Fragment Hits Unlock Active Chemical Matter Using Targeted Exploration of Vast Chemical Spaces. J.Med.Chem., 65, 2022
8EX3	Plasmodium falciparum M1 in complex with inhibitor 9aa 分子名称: GLYCEROL, M1 family aminopeptidase, MAGNESIUM ION, ... 著者 Calic, P.P.S, McGowan, S, Webb, C.T. 登録日 2022-10-24 公開日 2023-01-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Structure-based development of potent Plasmodium falciparum M1 and M17 aminopeptidase selective and dual inhibitors via S1'-region optimisation. Eur.J.Med.Chem., 248, 2022
7PIG	Protein kinase A catalytic subunit in complex with PKI5-24 and EN088 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 6-azanyl-2-chloranyl-3-[(Z)-piperidin-3-ylidenemethyl]benzenecarbonitrile, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Glinca, S, Mueller, J.M, Ruf, M, Merkl, S. 登録日 2021-08-19 公開日 2022-09-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.553 Å) 主引用文献 Magnet for the Needle in Haystack: "Crystal Structure First" Fragment Hits Unlock Active Chemical Matter Using Targeted Exploration of Vast Chemical Spaces. J.Med.Chem., 65, 2022
8EYD	Plasmodium falciparum M1 in complex with inhibitor 15ah 分子名称: GLYCEROL, M1 family aminopeptidase, N-[(1R)-1-(4-bromophenyl)-2-(hydroxyamino)-2-oxoethyl]-N~2~-(4-fluorophenyl)glycinamide, ... 著者 Calic, P.P.S, McGowan, S, Webb, C.T. 登録日 2022-10-26 公開日 2023-01-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Structure-based development of potent Plasmodium falciparum M1 and M17 aminopeptidase selective and dual inhibitors via S1'-region optimisation. Eur.J.Med.Chem., 248, 2022
7PIF	Protein kinase A catalytic subunit in complex with PKI5-24 and EN086 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-[3-[4-(aminomethyl)oxan-4-yl]phenyl]-2-azanyl-benzenecarbonitrile, CHLORIDE ION, ... 著者 Glinca, S, Mueller, J.M, Ruf, M, Merkl, S. 登録日 2021-08-19 公開日 2022-09-21 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.395 Å) 主引用文献 Magnet for the Needle in Haystack: "Crystal Structure First" Fragment Hits Unlock Active Chemical Matter Using Targeted Exploration of Vast Chemical Spaces. J.Med.Chem., 65, 2022

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