PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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7SZJ	Cryo-EM structure of Rifamycin bound to E. coli RNAP and rrnBP1 promoter complex 分子名称: DNA (49-MER), DNA (57-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Shin, Y, Murakami, K.S. 登録日 2021-11-28 公開日 2022-07-13 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (3.11 Å) 主引用文献 Optimization of Benzoxazinorifamycins to Improve Mycobacterium tuberculosis RNA Polymerase Inhibition and Treatment of Tuberculosis. Acs Infect Dis., 8, 2022
7EDX	p53-bound TFIID-based core PIC on HDM2 promoter 分子名称: DNA (84-mer), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. 登録日 2021-03-17 公開日 2021-05-05 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EG7	TFIID-based core PIC on SCP promoter 分子名称: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. 登録日 2021-03-24 公開日 2021-05-05 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EG9	TFIID-based intermediate PIC on SCP promoter 分子名称: DNA (79-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Qi, Y, Wang, X, Wu, Z, Li, J, Xu, Y. 登録日 2021-03-24 公開日 2021-05-05 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EGA	TFIID-based intermediate PIC on PUMA promoter 分子名称: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Wu, Z, Hou, H, Qi, Y, Wang, X, Li, J, Xu, Y. 登録日 2021-03-24 公開日 2021-05-05 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7EG8	TFIID-based core PIC on PUMA promoter 分子名称: DNA (85-MER), DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... 著者 Chen, X, Qi, Y, Hou, H, Wang, X, Wu, Z, Li, J, Xu, Y. 登録日 2021-03-24 公開日 2021-05-05 最終更新日 2021-05-19 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Structural insights into preinitiation complex assembly on core promoters. Science, 372, 2021
7C97	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA 分子名称: DNA (63-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lin, W, Feng, Y. 登録日 2020-06-05 公開日 2020-08-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
8Y6U	Cryo-EM structure of E.coli transcription initiation complex with transcription factor GcvA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Shi, J. 登録日 2024-02-03 公開日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.97 Å) 主引用文献 NMR analysis of a loop-bulge structure of UUCGA pentaloop. Biochem.Biophys.Res.Commun., 691, 2024
1HI0	RNA dependent RNA polymerase from dsRNA bacteriophage phi6 plus initiation complex 分子名称: DNA (5'-(*TP*TP*TP*CP*C)-3'), GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Grimes, J.M, Butcher, S.J, Makeyev, E.V, Bamford, D.H, Stuart, D.I. 登録日 2000-12-31 公開日 2001-03-27 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A Mechanism for Initiating RNA-Dependent RNA Polymerization Nature, 410, 2001
5UH6	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2ntRNA in complex with Rifampin 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.837 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
7CHW	Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) 分子名称: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lin, W, Feng, Y. 登録日 2020-07-06 公開日 2020-08-12 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Structural basis for transcription inhibition by E. coli SspA Nucleic Acids Res., 2020
7AE1	Cryo-EM structure of human RNA Polymerase III elongation complex 1 分子名称: DNA-directed RNA polymerase III subunit RPC1, DNA-directed RNA polymerase III subunit RPC10, DNA-directed RNA polymerase III subunit RPC2, ... 著者 Girbig, M, Misiaszek, A.D, Vorlaender, M.K, Mueller, C.W. 登録日 2020-09-17 公開日 2021-02-03 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Cryo-EM structures of human RNA polymerase III in its unbound and transcribing states. Nat.Struct.Mol.Biol., 28, 2021
4O42	Tandem chromodomains of human CHD1 in complex with influenza NS1 C-terminal tail dimethylated at K229 分子名称: Chromodomain-helicase-DNA-binding protein 1, GLYCEROL, Nonstructural protein 1, ... 著者 Qin, S, Xu, C, Tempel, W, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC) 登録日 2013-12-18 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Structural basis for histone mimicry and hijacking of host proteins by influenza virus protein NS1. Nat Commun, 5, 2014
5UHF	Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-IX336 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (4.345 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
5UH9	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 2nt RNA 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (4.402 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
5UHC	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3nt RNA in complex with Rifampin 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (3.796 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
5UHB	Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with Rifampin 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (4.29 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
6DM7	NMR structure for Sp1 transcription factor duplex 5'-d(GGGGCGGGG) 分子名称: DNA (5'-D(*CP*CP*CP*CP*GP*CP*CP*CP*C)-3'), DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*G)-3') 著者 Davis, E.V, Hennig, M, Arya, D.P. 登録日 2018-06-04 公開日 2019-06-12 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 An NMR Structure Determination and Analysis of Four Sp1 Consensus Sequences To Be Published
6DXM	NMR structure for Sp1 transcription factor duplex 5'-d(TGGGCGGGG) 分子名称: DNA (5'-D(*CP*CP*CP*CP*GP*CP*CP*CP*A)-3'), DNA (5'-D(*TP*GP*GP*GP*CP*GP*GP*GP*G)-3') 著者 Davis, E.V, Hennig, M, Arya, D.P. 登録日 2018-06-29 公開日 2019-07-03 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 An NMR Structure Determination and Analysis of Four Sp1 Consensus Sequences To Be Published
6DVT	NMR structure for Sp1 transcription factor duplex 5'-d(GGGGCGGGA) 分子名称: DNA (5'-D(*GP*GP*GP*GP*CP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*GP*CP*CP*CP*C)-3') 著者 Davis, E.V, Hennig, M, Arya, D.P. 登録日 2018-06-25 公開日 2019-07-03 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 An NMR Structure Determination and Analysis of Four Sp1 Consensus Sequences To Be Published
6CUX	Escherichia coli RpoB S531L mutant RNA polymerase holoenzyme in complex with Kanglemycin A 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Molodtsov, V, Murakami, K.S. 登録日 2018-03-26 公開日 2018-07-25 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (4.104 Å) 主引用文献 Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis. Mol. Cell, 72, 2018
4XSX	Crystal structure of CBR 703 bound to Escherichia coli RNA polymerase holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Bae, B, Darst, S.A. 登録日 2015-01-22 公開日 2015-07-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.708 Å) 主引用文献 CBR antimicrobials inhibit RNA polymerase via at least two bridge-helix cap-mediated effects on nucleotide addition. Proc.Natl.Acad.Sci.USA, 112, 2015
5UHE	Crystal structure of Mycobacterium tuberculosis transcription initiation complex in complex with D-AAP1 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.039 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
5UH5	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 3 nt of RNA 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-10 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.746 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017
5UHD	Crystal structure of Mycobacterium tuberculosis transcription initiation complex containing 4nt RNA in complex with Rifampin 分子名称: DNA (5'-D(*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2017-01-11 公開日 2017-04-12 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.01 Å) 主引用文献 Structural Basis of Mycobacterium tuberculosis Transcription and Transcription Inhibition. Mol. Cell, 66, 2017

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