PDB: 222624 件ウェブページステータス検索Chemie searchBIRD

---

8WLL	Cryo-EM structure of human VMAT2 Y422C, in the presence of reserpine, determined in an inward-facing conformation 分子名称: Synaptic vesicular amine transporter, reserpine 著者 Qu, Q, Wang, Y, Zhou, Z. 登録日 2023-09-30 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.74 Å) 主引用文献 Cryo-EM structure of human VMAT2 Y422C, in the presence of reserpine, determined in an inward-facing conformation To Be Published
8WLK	Cryo-EM structure of human VMAT2 in presence of Tetrabenazine, determined in an outward-facing conformation 分子名称: (3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one, Synaptic vesicular amine transporter 著者 Qu, Q, Wang, Y, Zhou, Z. 登録日 2023-09-30 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.37 Å) 主引用文献 Cryo-EM structure of human apo VMAT2 in an outward-facing conformation To Be Published
8WLJ	Cryo-EM structure of human apo VMAT2 with nanobody in an outward-facing conformation 分子名称: Synaptic vesicular amine transporter, nanobody 著者 Qu, Q, Wang, Y, Zhou, Z. 登録日 2023-09-30 公開日 2024-06-12 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structure of human apo VMAT2 in an outward-facing conformation To Be Published
8WLG	Crystal structure of Cypovirus Polyhedra mutant fused with c-Myc fragment 分子名称: Polyhedrin,Myc proto-oncogene protein 著者 Kojima, M, Ueno, T, Abe, S, Hirata, K. 登録日 2023-09-29 公開日 2024-06-05 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 High-throughput structure determination of an intrinsically disordered protein using cell-free protein crystallization. Proc.Natl.Acad.Sci.USA, 121, 2024
8WLB	X-ray structure of Enterobacter cloacae allose-binding protein in complex with D-psicose 分子名称: Allose ABC transporter, alpha-D-psicopyranose 著者 Kamitori, S. 登録日 2023-09-29 公開日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 X-ray structures of Enterobacter cloacae allose-binding protein in complexes with monosaccharides demonstrate its unique recognition mechanism for high affinity to allose. Biochem.Biophys.Res.Commun., 682, 2023
8WL9	X-ray structure of Enterobacter cloacae allose-binding protein in complex with D-ribose 分子名称: Allose ABC transporter, beta-D-ribopyranose 著者 Kamitori, S. 登録日 2023-09-29 公開日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 X-ray structures of Enterobacter cloacae allose-binding protein in complexes with monosaccharides demonstrate its unique recognition mechanism for high affinity to allose. Biochem.Biophys.Res.Commun., 682, 2023
8WL7	X-ray structure of Enterobacter cloacae allose-binding protein in complex with D-allose 分子名称: Allose ABC transporter, beta-D-allopyranose 著者 Kamitori, S. 登録日 2023-09-29 公開日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 X-ray structures of Enterobacter cloacae allose-binding protein in complexes with monosaccharides demonstrate its unique recognition mechanism for high affinity to allose. Biochem.Biophys.Res.Commun., 682, 2023
8WL5	X-ray structure of Enterobacter cloacae allose-binding protein in free form 分子名称: 1,2-ETHANEDIOL, Allose ABC transporter 著者 Kamitori, S. 登録日 2023-09-29 公開日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 X-ray structures of Enterobacter cloacae allose-binding protein in complexes with monosaccharides demonstrate its unique recognition mechanism for high affinity to allose. Biochem.Biophys.Res.Commun., 682, 2023
8WKX	Cryo-EM structure of DSR2 分子名称: SIR2-like domain-containing protein 著者 Gao, A, Huang, J, Zhu, K. 登録日 2023-09-28 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.15 Å) 主引用文献 Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion. Nat Commun, 15, 2024
8WKU	Complex structure of MjHKU4r-CoV-1 spike RBD bound to human CD26 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Dipeptidyl peptidase 4 soluble form, MjHKU4r-CoV-1 spike RBD, ... 著者 Zhao, Z.N, Chai, Y, Gao, F. 登録日 2023-09-28 公開日 2024-06-26 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Molecular basis for receptor recognition and broad host tropism for merbecovirus MjHKU4r-CoV-1. Embo Rep., 2024
8WKT	Cryo-EM structure of DSR2-DSAD1 complex 分子名称: SIR2-like domain-containing protein, SPbeta prophage-derived uncharacterized protein YotI 著者 Gao, A, Huang, J, Zhu, K. 登録日 2023-09-28 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.86 Å) 主引用文献 Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion. Nat Commun, 15, 2024
8WKS	Cryo-EM structure of DSR2-TUBE complex 分子名称: SIR2-like domain-containing protein, TUBE 著者 Gao, A, Huang, J, Zhu, K. 登録日 2023-09-28 公開日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.58 Å) 主引用文献 Molecular basis of bacterial DSR2 anti-phage defense and viral immune evasion. Nat Commun, 15, 2024
8WKR	Crystal structure of O-acetylhomoserine sulfhydrylase from Lactobacillus plantarum in the open form 分子名称: (2S)-2-amino-6-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]hexanoic acid, L-methionine gamma-lyase, PROLINE 著者 Oda, K, Matoba, Y. 登録日 2023-09-28 公開日 2024-02-14 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 pH-dependent regulation of an acidophilic O -acetylhomoserine sulfhydrylase from Lactobacillus plantarum. Appl.Environ.Microbiol., 90, 2024
8WKP	Structural basis of translation inhibition by a valine tRNA-derived fragment 分子名称: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... 著者 Wang, Y.H, Zhou, J. 登録日 2023-09-28 公開日 2024-04-10 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (4.62 Å) 主引用文献 Structural basis of translation inhibition by a valine tRNA-derived fragment. Life Sci Alliance, 7, 2024
8WKO	Crystal structure of O-acetylhomoserine sulfhydrylase from Lactobacillus plantarum in the closed form 分子名称: (2S)-2-amino-6-[[3-hydroxy-2-methyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]hexanoic acid, L-methionine gamma-lyase, PROLINE, ... 著者 Oda, K, Matoba, Y. 登録日 2023-09-28 公開日 2024-02-14 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.91 Å) 主引用文献 pH-dependent regulation of an acidophilic O -acetylhomoserine sulfhydrylase from Lactobacillus plantarum. Appl.Environ.Microbiol., 90, 2024
8WKN	Cryo-EM structure of DSR2-DSAD1 分子名称: SIR2-like domain-containing protein, SPbeta prophage-derived uncharacterized protein YotI 著者 Zhang, H, Li, Z, Li, X.Z. 登録日 2023-09-28 公開日 2024-05-01 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Insights into the modulation of bacterial NADase activity by phage proteins. Nat Commun, 15, 2024
8WKL	Rauvolfia serpentina strictosidine synthase (RsSTR) in complex with a non-reactive tryptamine substitute crystallized in P1211 space group 分子名称: 2-(2-methyl-1H-indol-3-yl)ethanamine, DI(HYDROXYETHYL)ETHER, Strictosidine synthase 著者 Nitin, K, Rajakumara, E. 登録日 2023-09-28 公開日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.67 Å) 主引用文献 Proxy-approach in understanding the bisubstrate activity of strictosidine synthases. Int.J.Biol.Macromol., 262, 2024
8WKJ	The crystal structure of aspartate aminotransferases Lpg0070 from Legionella pneumophila 分子名称: Aminotransferase, PYRIDOXAL-5'-PHOSPHATE 著者 Gao, Y.S, Hua, L, Xie, R. 登録日 2023-09-27 公開日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of an aspartate aminotransferase Lpg0070 from Legionella pneumophila. Biochem.Biophys.Res.Commun., 689, 2023
8WKH	Crystal structure of group 13 allergen from Blomia tropicalis 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, Fatty acid-binding protein 著者 Zhu, K.L, Gong, Y, Cui, Y.B. 登録日 2023-09-27 公開日 2023-11-22 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Immunobiological properties and structure analysis of group 13 allergen from Blomia tropicalis and its IgE-mediated cross-reactivity. Int.J.Biol.Macromol., 254, 2023
8WJY	PKMYT1_Cocrystal_Cpd 4 分子名称: DIMETHYL SULFOXIDE, GLYCEROL, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, ... 著者 Wang, Y, Wang, C, Liu, T, Qi, H, Chen, S, Cai, X, Zhang, M, Aliper, A, Ren, F, Ding, X, Zhavoronkov, A. 登録日 2023-09-26 公開日 2023-11-22 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Discovery of Tetrahydropyrazolopyrazine Derivatives as Potent and Selective MYT1 Inhibitors for the Treatment of Cancer. J.Med.Chem., 67, 2024
8WJO	Cryo-EM structure of 8-subunit Smc5/6 arm region 分子名称: DNA repair protein KRE29, E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, ... 著者 Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L. 登録日 2023-09-26 公開日 2024-06-26 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (6.04 Å) 主引用文献 Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
8WJN	Cryo-EM structure of 6-subunit Smc5/6 head region 分子名称: Non-structural maintenance of chromosome element 3, Non-structural maintenance of chromosomes element 1, Non-structural maintenance of chromosomes element 4, ... 著者 Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L. 登録日 2023-09-26 公開日 2024-06-26 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (5.58 Å) 主引用文献 Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
8WJL	Cryo-EM structure of 6-subunit Smc5/6 hinge region 分子名称: E3 SUMO-protein ligase MMS21, Structural maintenance of chromosomes protein 5, Structural maintenance of chromosomes protein 6 著者 Li, Q, Zhang, J, Zhang, X, Cheng, T, Wang, Z, Jin, D, Chen, Z, Wang, L. 登録日 2023-09-26 公開日 2024-06-26 最終更新日 2024-07-03 実験手法 ELECTRON MICROSCOPY (6.15 Å) 主引用文献 Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
8WIU	Bromodomain and Extra-terminal Domain (BET) BRD4 分子名称: 7-[5-[1-(cyclopropylmethyl)-3,5-dimethyl-pyrazol-4-yl]pyridin-3-yl]-1~{H}-imidazo[4,5-b]pyridine, Isoform C of Bromodomain-containing protein 4 著者 Cao, D, Zhiyan, D, Xiong, B. 登録日 2023-09-25 公開日 2024-01-03 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Discovery of a brain-permeable bromodomain and extra terminal domain (BET) inhibitor with selectivity for BD1 for the treatment of multiple sclerosis. Eur.J.Med.Chem., 265, 2023
8WIM	Crystal structure of Jingmen tick virus RNA-dependent RNA polymerase (D307 construct) 分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Jingmen tick virus NSP1, ... 著者 Wang, X, Jing, X, Deng, F, Gong, P. 登録日 2023-09-24 公開日 2024-01-17 最終更新日 2024-04-24 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 A jingmenvirus RNA-dependent RNA polymerase structurally resembles the flavivirus counterpart but with different features at the initiation phase. Nucleic Acids Res., 52, 2024

<56575859606162636465666768697071>