PDB: 20505 件ウェブページステータス検索Chemie searchBIRD

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4PE1	Crystal Structure of Calcium-loaded S100B bound to SC124 分子名称: CALCIUM ION, DIETHYLCARBAMODITHIOIC ACID, Protein S100-B 著者 Cavalier, M.C, Pierce, A.D, Wilder, P.T, Neau, D, Toth, E.A, Weber, D.J. 登録日 2014-04-22 公開日 2014-10-15 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.576 Å) 主引用文献 Covalent Small Molecule Inhibitors of Ca(2+)-Bound S100B. Biochemistry, 53, 2014
6Y91	Crystal structure of malate dehydrogenase from Plasmodium Falciparum in complex with NADH 分子名称: Malate dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Romero, A.R, Calderone, V, Gentili, M, Lunev, S, Groves, M, Popowicz, G, Domling, A, Sattler, M. 登録日 2020-03-06 公開日 2021-03-31 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A fragment-based approach identifies an allosteric pocket that impacts malate dehydrogenase activity. Commun Biol, 4, 2021
1OL0	Crystal structure of a camelised human VH 分子名称: GLYCEROL, IMMUNOGLOBULIN G, SULFATE ION 著者 Dottorini, T, Vaughan, C.K, Walsh, M.A, Losurdo, P, Sollazzo, M. 登録日 2003-08-02 公開日 2004-01-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of a Human Vh: Requirements for Maintaining a Monomeric Fragment Biochemistry, 43, 2004
1OIA	U1A rnp domain 1-95 分子名称: U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A 著者 Nagai, K, Evans, P.R. 登録日 2003-06-12 公開日 2003-06-26 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure of the RNA-Binding Domain of the U1 Small Nuclear Ribonucleoprotein A Nature, 348, 1990
1OED	STRUCTURE OF ACETYLCHOLINE RECEPTOR PORE FROM ELECTRON IMAGES 分子名称: Acetylcholine receptor beta subunit, Acetylcholine receptor delta subunit, Acetylcholine receptor gamma subunit, ... 著者 Miyazawa, A, Fujiyoshi, Y, Unwin, N. 登録日 2003-03-24 公開日 2003-06-26 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structure and Gating Mechanism of the Acetylcholine Receptor Pore. Nature, 423, 2003
5VAR	Crystal structure of KDM4A tandem TUDOR domain in complex with a tri-methyl lysine competitive inhibitor 分子名称: (1R,2S,3R,4S)-3-[(dimethylamino)methyl]-1-phenylbicyclo[2.2.1]heptan-2-ol, Lysine-specific demethylase 4A 著者 Judge, R.A, Upadhyay, A.K. 登録日 2017-03-27 公開日 2018-03-28 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Targeting lysine specific demethylase 4A (KDM4A) tandem TUDOR domain - A fragment based approach. Bioorg. Med. Chem. Lett., 28, 2018
6ZMN	Crystal structure of the Smad3-Smad5 MH1 domain chimera bound to the GGCGC site 分子名称: 1,2-ETHANEDIOL, ACETATE ION, DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP*GP*CP*A)-3'), ... 著者 Pluta, R, Macias, M.J. 登録日 2020-07-03 公開日 2020-08-26 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.333 Å) 主引用文献 Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes. Comput Struct Biotechnol J, 19, 2021
6ZQT	Crystal structure of the RLIP76 Ral binding domain mutant (E427H/Q433L/K440R) in complex with RalB-GMPPNP 分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Hurd, C, Brear, P, Revell, J, Ross, S, Mott, H, Owen, D. 登録日 2020-07-10 公開日 2020-11-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases. J.Biol.Chem., 296, 2020
7AAB	Crystal structure of the catalytic domain of human PARP1 in complex with inhibitor EB-47 分子名称: 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide, Poly [ADP-ribose] polymerase 1, SULFATE ION 著者 Schimpl, M, Ogden, T.E.H, Yang, J.-C, Easton, L.E, Underwood, E, Rawlins, P.B, Johannes, J.W, Embrey, K.J, Neuhaus, D. 登録日 2020-09-04 公開日 2021-01-13 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition. Nucleic Acids Res., 49, 2021
7AAA	Crystal structure of the catalytic domain of human PARP1 (apo) 分子名称: 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... 著者 Schimpl, M, Ogden, T.E.H, Yang, J.-C, Underwood, E, Rawlins, P.B, Johannes, J.W, Easton, L.E, Embrey, K.J, Neuhaus, D. 登録日 2020-09-04 公開日 2021-01-13 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition. Nucleic Acids Res., 49, 2021
6ZRN	Crystal structure of the RLIP76 Ral binding domain mutant (E427S/L429M/Q433L/K440R) in complex with RalB-GMPPNP 分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Hurd, C, Brear, P, Revell, J, Ross, S, Mott, H, Owen, D. 登録日 2020-07-13 公開日 2020-11-25 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.482 Å) 主引用文献 Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases. J.Biol.Chem., 296, 2020
5T7A	Crystal structure of Br derivative BhCBM56 分子名称: 1,2-ETHANEDIOL, BH0236 protein, BROMIDE ION 著者 Pluvinage, B, Boraston, A.B. 登録日 2016-09-02 公開日 2017-08-23 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Properties of a family 56 carbohydrate-binding module and its role in the recognition and hydrolysis of beta-1,3-glucan. J. Biol. Chem., 292, 2017
1QRV	CRYSTAL STRUCTURE OF THE COMPLEX OF HMG-D AND DNA 分子名称: DNA (5'-D(*GP*CP*GP*AP*TP*AP*TP*CP*GP*C)-3'), HIGH MOBILITY GROUP PROTEIN D, SODIUM ION 著者 Murphy IV, F.V, Sweet, R.M, Churchill, M.E.A. 登録日 1999-06-15 公開日 1999-12-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The structure of a chromosomal high mobility group protein-DNA complex reveals sequence-neutral mechanisms important for non-sequence-specific DNA recognition. EMBO J., 18, 1999
6I6E	Circular permutant of ribosomal protein S6, swap strand 1 , L10A mutant 分子名称: 30S ribosomal protein S6 著者 Wang, H, Logan, D.T, Oliveberg, M. 登録日 2018-11-15 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
6RMA	Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... 著者 Hamann, F, Neumann, P, Ficner, R. 登録日 2019-05-06 公開日 2020-02-05 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2. Proc.Natl.Acad.Sci.USA, 117, 2020
6I69	Circular permutant of ribosomal protein S6, adding 5aa to C terminal of P97-3, L10A mutant 分子名称: 30S ribosomal protein S6 著者 Wang, H, Logan, D.T, Oliveberg, M. 登録日 2018-11-15 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
7JXR	Crystal Structure Human Immunodeficiency Virus-1 Matrix protein Mutant Q63R Crystal Form 1 分子名称: HEXAETHYLENE GLYCOL, Matrix protein, SULFATE ION 著者 Green, T.J, Eastep, G.N, Ghanam, R.H, Saad, J.S. 登録日 2020-08-27 公開日 2021-04-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Structural characterization of HIV-1 matrix mutants implicated in envelope incorporation. J.Biol.Chem., 296, 2021
7JXS	Crystal Structure Human Immunodeficiency Virus-1 Matrix protein Mutant Q63R Crystal Form 2 分子名称: ACETATE ION, DODECAETHYLENE GLYCOL, HEXAETHYLENE GLYCOL, ... 著者 Green, T.J, Eastep, G.N, Ghanam, R.H, Saad, J.S. 登録日 2020-08-27 公開日 2021-04-14 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structural characterization of HIV-1 matrix mutants implicated in envelope incorporation. J.Biol.Chem., 296, 2021
6I6U	Circular permutant of ribosomal protein S6, adding 9aa to N terminal of P81-82, L75A mutant 分子名称: 30S ribosomal protein S6,30S ribosomal protein S6 著者 Wang, H, Logan, D.T, Oliveberg, M. 登録日 2018-11-15 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Exposing the distinctive modular behavior of beta-strands and alpha-helices in folded proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
1BJA	ACTIVATION DOMAIN OF THE PHAGE T4 TRANSCRIPTION FACTOR MOTA 分子名称: SULFATE ION, TRANSCRIPTION REGULATORY PROTEIN MOTA 著者 Finnin, M.S, Cicero, M.P, Davies, C, Porter, S.J, White, S.W, Kreuzer, K.N. 登録日 1998-06-23 公開日 1998-11-04 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 The activation domain of the MotA transcription factor from bacteriophage T4. EMBO J., 16, 1997
6SQ0	ERa_L536S (L536S/C381S/C471S,C530S) in complex with a bridged tetracyclic indole (compound 8) 分子名称: Bridged tetracyclic indole, Estrogen receptor 著者 Breed, J. 登録日 2019-09-03 公開日 2019-10-30 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Building Bridges in a Series of Estrogen Receptor Degraders: An Application of Metathesis in Medicinal Chemistry. Acs Med.Chem.Lett., 10, 2019
1C1Z	CRYSTAL STRUCTURE OF HUMAN BETA-2-GLYCOPROTEIN-I (APOLIPOPROTEIN-H) 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, BETA2-GLYCOPROTEIN-I, ... 著者 Schwarzenbacher, R, Zeth, K, Diederichs, K, Gries, A, Kostner, G.M, Laggner, P, Prassl, R. 登録日 1999-07-22 公開日 1999-11-19 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.87 Å) 主引用文献 Crystal structure of human beta2-glycoprotein I: implications for phospholipid binding and the antiphospholipid syndrome. EMBO J., 18, 1999
6SYG	Crystal structure of the Cyclic Nucleotide-Binding Homology Domain of the human KCNH2 channel 分子名称: Potassium voltage-gated channel subfamily H member 2 著者 Ben-Bassat, A, Giladi, M, Haitin, Y. 登録日 2019-09-27 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structure of KCNH2 cyclic nucleotide-binding homology domain reveals a functionally vital salt-bridge. J.Gen.Physiol., 152, 2020
6TBZ	Crystal structure of the MH1 domain of Smad5-Smad3 chimera construct bound to the GGCGC site 分子名称: DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*GP*CP*GP*CP*CP*TP*GP*CP*A)-3'), Mothers against decapentaplegic homolog 5, ZINC ION 著者 Pluta, R, Macias, M.J. 登録日 2019-11-04 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.782 Å) 主引用文献 Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes. Comput Struct Biotechnol J, 19, 2021
6TCE	Crystal structure of the GGCT site-bound MH1 domain of Smad5 containing a GGGS insertion in the Loop1 分子名称: DNA (5'-D(P*TP*GP*CP*AP*GP*GP*CP*TP*AP*GP*CP*CP*TP*GP*CP*A)-3'), Mothers against decapentaplegic homolog 5, ZINC ION 著者 Pluta, R, Macias, M.J. 登録日 2019-11-05 公開日 2019-11-20 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Unveiling the dimer/monomer propensities of Smad MH1-DNA complexes. Comput Struct Biotechnol J, 19, 2021

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