6ZRN

Crystal structure of the RLIP76 Ral binding domain mutant (E427S/L429M/Q433L/K440R) in complex with RalB-GMPPNP

Summary for 6ZRN

• Entry DOI: 10.2210/pdb6zrn/pdb
• Descriptor: Ras-related protein Ral-B, RalA-binding protein 1, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (6 entities in total)
• Functional Keywords: ralb, rlip76, ral binding domain, coiled-coil, small gtpase, g protein, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 56988.45

Authors

Hurd, C.,Brear, P.,Revell, J.,Ross, S.,Mott, H.,Owen, D. (deposition date: 2020-07-13, release date: 2020-11-25, Last modification date: 2024-01-31)

• Primary citation: Hurd, C.A.,Brear, P.,Revell, J.,Ross, S.,Mott, H.R.,Owen, D.; Affinity maturation of the RLIP76 Ral binding domain to inform the design of stapled peptides targeting the Ral GTPases.; J.Biol.Chem., 296:100101-100101, 2020; PubMed: 33214225; DOI: 10.1074/jbc.RA120.015735

Experimental method

X-RAY DIFFRACTION (1.482 Å)