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5LV0
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BU of 5lv0 by Molmil
Structure of Human Neurolysin (E475Q) in complex with amyloid-beta 35-40 peptide product
分子名称: CHLORIDE ION, GLY-VAL-VAL amyloid 35-40 fragment, Neurolysin, ...
著者Masuyer, G, Berntsson, R.P.-A, Teixeira, P.F, Kmiec, B, Glaser, E, Stenmark, P.
登録日2016-09-12
公開日2017-12-06
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and functional analysis of Neurolysin, a new component of the mitochondrial peptidolytic network
To Be Published
5LTS
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BU of 5lts by Molmil
Crystal structure of Lymphocytic choriomeningitis mammarenavirus endonuclease Mutant D118A
分子名称: CHLORIDE ION, GLYCEROL, RNA-directed RNA polymerase L, ...
著者Saez-Ayala, M, Yekwa, E.L, Canard, B, Alvarez, K, Ferron, F.
登録日2016-09-07
公開日2017-09-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
IUCrJ, 5, 2018
8UFC
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BU of 8ufc by Molmil
Eastern equine encephalitis virus (PE-6) VLP in complex with VLDLR LA(1-2) (asymmetric unit)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Capsid protein, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
登録日2023-10-04
公開日2024-01-17
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
5KBN
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BU of 5kbn by Molmil
The crystal structure of fluoride channel Fluc Ec2 F80I Mutant
分子名称: DECYL-BETA-D-MALTOPYRANOSIDE, FLUORIDE ION, Putative fluoride ion transporter CrcB, ...
著者Last, N.B, Kolmakova-Partensky, L, Shane, T, Miller, C.
登録日2016-06-03
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Mechanistic signs of double-barreled structure in a fluoride ion channel.
Elife, 5, 2016
8UFA
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BU of 8ufa by Molmil
Eastern equine encephalitis virus (PE-6) VLP (asymmetric unit)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, E1 protein, ...
著者Adams, L.J, Fremont, D.H, Center for Structural Biology of Infectious Diseases (CSBID)
登録日2023-10-04
公開日2024-01-17
最終更新日2024-01-31
実験手法ELECTRON MICROSCOPY (2.86 Å)
主引用文献Structural and functional basis of VLDLR usage by Eastern equine encephalitis virus.
Cell, 187, 2024
1CDT
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BU of 1cdt by Molmil
CARDIOTOXIN V4/II FROM NAJA MOSSAMBICA MOSSAMBICA: THE REFINED CRYSTAL STRUCTURE
分子名称: CARDIOTOXIN VII4, PHOSPHATE ION
著者Rees, B, Bilwes, A, Samama, J.P, Moras, D.
登録日1990-05-17
公開日1991-07-15
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Cardiotoxin VII4 from Naja mossambica mossambica. The refined crystal structure.
J.Mol.Biol., 214, 1990
1C6V
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BU of 1c6v by Molmil
SIV INTEGRASE (CATALYTIC DOMAIN + DNA BIDING DOMAIN COMPRISING RESIDUES 50-293) MUTANT WITH PHE 185 REPLACED BY HIS (F185H)
分子名称: PROTEIN (SIU89134), PROTEIN (SIV INTEGRASE)
著者Chen, Z, Yan, Y, Munshi, S, Li, Y, Zruygay-Murphy, J, Xu, B, Witmer, M, Felock, P, Wolfe, A, Sardana, V, Emini, E.A, Hazuda, D, Kuo, L.C.
登録日1999-12-21
公開日2000-12-27
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform.
J.Mol.Biol., 296, 2000
6FS9
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BU of 6fs9 by Molmil
Influenza B/Memphis/13/03 endonuclease with I38T mutation with bound inhibitor, baloxavir acid (BXA)
分子名称: Baloxavir acid, CHLORIDE ION, MANGANESE (II) ION, ...
著者Cusack, S, Speranzini, V.
登録日2018-02-19
公開日2018-07-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil.
Sci Rep, 8, 2018
7LWQ
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BU of 7lwq by Molmil
Mink Cluster 5-associated SARS-CoV-2 spike protein(S-GSAS-D614G-delFV) missing the S1 subunit and SD2 subdomain of one protomer
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Gobeil, S, Acharya, P.
登録日2021-03-01
公開日2021-03-31
最終更新日2021-08-18
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity.
Science, 373, 2021
8IUX
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BU of 8iux by Molmil
The cryoEM structure of H7N9-HA protein
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin
著者Zhao, B.B, Sun, Z.Z.
登録日2023-03-25
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献The cryoEM structure of H7N9-HA protein
To Be Published
6HPQ
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BU of 6hpq by Molmil
Crystal structure of human Pif1 helicase in complex with AMP-PNP, brominated crystal form.
分子名称: ATP-dependent DNA helicase PIF1, BROMIDE ION, MAGNESIUM ION, ...
著者Ledikov, V.M, Dehghani-Tafti, S, Bax, B, Sanders, C.M, Antson, A.A.
登録日2018-09-21
公開日2019-01-23
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.43 Å)
主引用文献Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase.
Nucleic Acids Res., 47, 2019
8IV0
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BU of 8iv0 by Molmil
H7N9 HA-C4H4 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C4H4 Fab heavy chain, C4H4 Fab light chain, ...
著者Zhao, B.B, Sun, Z.Z.
登録日2023-03-25
公開日2024-04-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献H7N9 HA-C4H4 Fab
To Be Published
5M11
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BU of 5m11 by Molmil
Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.
分子名称: CACODYLATE ION, CALCIUM ION, CHLORIDE ION, ...
著者Lasica, A.M, Goulas, T, Mizgalska, D, Zhou, X, Ksiazek, M, Madej, M, Guo, Y, Guevara, T, Nowak, M, Potempa, B, Goel, A, Sztukowska, M, Prabhakar, A.T, Bzowska, M, Widziolek, M, Thogersen, I.B, Enghild, J.J, Simonian, M, Kulczyk, A.W, Nguyen, K.-A, Potempa, J, Gomis-Ruth, F.X.
登録日2016-10-07
公開日2016-11-09
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.
Sci Rep, 6, 2016
7BM8
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BU of 7bm8 by Molmil
Crystal structure of the C-terminally truncated chromosome-partitioning protein ParB from Caulobacter crescentus complexed with CTP-gamma-S
分子名称: CYTIDINE-5'-TRIPHOSPHATE, Chromosome-partitioning protein ParB, MAGNESIUM ION
著者Jalal, A.S, Tran, N.T, Stevenson, C.E.M, Lawson, D.M, Le, T.B.K.
登録日2021-01-19
公開日2021-04-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献A CTP-dependent gating mechanism enables ParB spreading on DNA.
Elife, 10, 2021
5CL7
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BU of 5cl7 by Molmil
Alkylpurine DNA glycosylase AlkD bound to DNA containing a 3-methyladenine analog or DNA containing an abasic site and a free nucleobase (18% substrate/82% product at 96 hours)
分子名称: 7-methyl-3H-imidazo[4,5-c]pyridin-4-amine, AlkD, DNA (5'-D(*CP*CP*CP*GP*AP*(DZM)P*AP*GP*TP*CP*CP*G)-3'), ...
著者Mullins, E.A, Eichman, B.F.
登録日2015-07-16
公開日2015-10-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献The DNA glycosylase AlkD uses a non-base-flipping mechanism to excise bulky lesions.
Nature, 527, 2015
6T3G
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BU of 6t3g by Molmil
3C-like protease from Southampton virus complexed with FMOPL000324a.
分子名称: 3-chloro-N-(1-hydroxy-2-methylpropan-2-yl)benzamide, DIMETHYL SULFOXIDE, Genome polyprotein, ...
著者Guo, J, Cooper, J.B.
登録日2019-10-10
公開日2020-09-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献In crystallo-screening for discovery of human norovirus 3C-like protease inhibitors.
J Struct Biol X, 4, 2020
5IER
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BU of 5ier by Molmil
Structure of a computationally designed 17-OHP binder
分子名称: (9beta)-17-hydroxypregn-4-ene-3,20-dione, OHP9, SODIUM ION, ...
著者Stoddard, B.L, Doyle, L.A.
登録日2016-02-25
公開日2017-03-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.005 Å)
主引用文献Sampling and energy evaluation challenges in ligand binding protein design.
Protein Sci., 26, 2017
6T3W
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BU of 6t3w by Molmil
Coxsackie B3 2C protein in complex with S-Fluoxetine
分子名称: (3S)-N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, 2C protein, SODIUM ION, ...
著者El Kazzi, P, Papageorgiou, N, Ferron, F.P, Bauer, L, van Kuppeveld, F, Coutard, B.
登録日2019-10-11
公開日2020-11-18
最終更新日2024-06-19
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Fluoxetine targets an allosteric site in the enterovirus 2C AAA+ ATPase and stabilizes a ring-shaped hexameric complex.
Sci Adv, 8, 2022
6BMC
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BU of 6bmc by Molmil
The structure of a dimeric type II DAH7PS associated with pyocyanin biosynthesis in Pseudomonas aeruginosa
分子名称: CHLORIDE ION, COBALT (II) ION, PHOSPHOENOLPYRUVATE, ...
著者Sterritt, O.W, Jameson, G.B, Parker, E.J.
登録日2017-11-14
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and functional characterisation of the entry point to pyocyanin biosynthesis inPseudomonas aeruginosadefines a new 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase subclass.
Biosci. Rep., 38, 2018
5EYL
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BU of 5eyl by Molmil
TUBULIN-BINDING DARPIN
分子名称: DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), GLYCEROL, PHOSPHATE ION
著者Ahmad, S, Kossow, M, Gigant, B.
登録日2015-11-25
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin.
Sci Rep, 6, 2016
7C1A
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BU of 7c1a by Molmil
Crystal structure of FumaraseC (S319C) from Mannheimia succiniciproducens in complex with malate
分子名称: (2S)-2-hydroxybutanedioic acid, Fumarate hydratase class II
著者Kim, B, Lee, S.H, Kim, K.-J.
登録日2020-05-02
公開日2021-05-05
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.144 Å)
主引用文献Structural and Biochemical analysis of FumaraseC from Mannheimia succiniciproducens
To Be Published
7LXZ
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BU of 7lxz by Molmil
SARS-CoV-2 S/S2M11/S2L28 Global Refinement
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-03-05
公開日2021-04-14
最終更新日2021-05-12
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献N-terminal domain antigenic mapping reveals a site of vulnerability for SARS-CoV-2.
Cell, 184, 2021
6FYS
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BU of 6fys by Molmil
Structure of single domain antibody SD83
分子名称: 1,2-ETHANEDIOL, Single domain antibody SD83
著者Laursen, N.S, Wilson, I.A.
登録日2018-03-12
公開日2018-11-07
最終更新日2022-03-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6PS7
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BU of 6ps7 by Molmil
XFEL A2aR structure by ligand exchange from LUF5843 to ZM241385.
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, ...
著者Ishchenko, A, Stauch, B, Han, G.W, Batyuk, A, Shiriaeva, A, Li, C, Zatsepin, N.A, Weierstall, U, Liu, W, Nango, E, Nakane, T, Tanaka, R, Tono, K, Joti, Y, Iwata, S, Moraes, I, Gati, C, Cherezov, C.
登録日2019-07-12
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Toward G protein-coupled receptor structure-based drug design using X-ray lasers.
Iucrj, 6, 2019
1C8V
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BU of 1c8v by Molmil
CRYSTAL STRUCTURE OF THE COMPLEX OF BACTERIAL TRYPTOPHAN SYNTHASE WITH THE TRANSITION STATE ANALOGUE INHIBITOR 4-(2-HYDROXYPHENYLTHIO)-BUTYLPHOSPHONIC ACID
分子名称: 4-(2-HYDROXYPHENYLTHIO)-1-BUTENYLPHOSPHONIC ACID, PYRIDOXAL-5'-PHOSPHATE, SODIUM ION, ...
著者Sachpatzidis, A, Dealwis, C, Lubetsky, J.B, Liang, P.H, Anderson, K.S, Lolis, E.
登録日1999-07-30
公開日2000-01-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic studies of phosphonate-based alpha-reaction transition-state analogues complexed to tryptophan synthase.
Biochemistry, 38, 1999

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