5LV0

Structure of Human Neurolysin (E475Q) in complex with amyloid-beta 35-40 peptide product

Summary for 5LV0

• Entry DOI: 10.2210/pdb5lv0/pdb
• Descriptor: Neurolysin, mitochondrial, GLY-VAL-VAL amyloid 35-40 fragment, ZINC ION, ... (5 entities in total)
• Functional Keywords: protease, mitochondria, hydrolase, amyloid-beta
• Biological source: Homo sapiens (Human); More
• Cellular location: Mitochondrion intermembrane space : Q9BYT8
• Total number of polymer chains: 4
• Total formula weight: 158612.70

Authors

Masuyer, G.,Berntsson, R.P.-A.,Teixeira, P.F.,Kmiec, B.,Glaser, E.,Stenmark, P. (deposition date: 2016-09-12, release date: 2017-12-06, Last modification date: 2024-01-17)

• Primary citation: Teixeira, P.F.,Masuyer, G.,Pinho, C.,Branca, R.M.M.,Kmiec, B.,Wallin, C.,Warmlander, S.,Berntsson, R.P.-A.,Ankarcrona, M.,Graslund, A.,Lehtio, J.,Stenmark, P.,Glaser, E.; Structural and functional analysis of Neurolysin, a new component of the mitochondrial peptidolytic network; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)