5LV0
Structure of Human Neurolysin (E475Q) in complex with amyloid-beta 35-40 peptide product
Summary for 5LV0
Entry DOI | 10.2210/pdb5lv0/pdb |
Descriptor | Neurolysin, mitochondrial, GLY-VAL-VAL amyloid 35-40 fragment, ZINC ION, ... (5 entities in total) |
Functional Keywords | protease, mitochondria, hydrolase, amyloid-beta |
Biological source | Homo sapiens (Human) More |
Cellular location | Mitochondrion intermembrane space : Q9BYT8 |
Total number of polymer chains | 4 |
Total formula weight | 158612.70 |
Authors | Masuyer, G.,Berntsson, R.P.-A.,Teixeira, P.F.,Kmiec, B.,Glaser, E.,Stenmark, P. (deposition date: 2016-09-12, release date: 2017-12-06, Last modification date: 2024-01-17) |
Primary citation | Teixeira, P.F.,Masuyer, G.,Pinho, C.,Branca, R.M.M.,Kmiec, B.,Wallin, C.,Warmlander, S.,Berntsson, R.P.-A.,Ankarcrona, M.,Graslund, A.,Lehtio, J.,Stenmark, P.,Glaser, E. Structural and functional analysis of Neurolysin, a new component of the mitochondrial peptidolytic network To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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