PDB: 37044 件ウェブページステータス検索Chemie searchBIRD

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3P3Z	Crystal Structure of the Cytochrome P450 Monooxygenase AurH from Streptomyces Thioluteus in Complex with Ancymidol 分子名称: (S)-cyclopropyl(4-methoxyphenyl)pyrimidin-5-ylmethanol, CHLORIDE ION, Cytochrome P450, ... 著者 Zocher, G, Richter, M.E.A, Mueller, U, Hertweck, C. 登録日 2010-10-05 公開日 2011-02-16 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural fine-tuning of a multifunctional cytochrome p450 monooxygenase. J.Am.Chem.Soc., 133, 2011
4G49	Room temperature X-ray diffraction of cisplatin binding to HEWL in aqueous media after 15 months of crystal storage 分子名称: ACETATE ION, CHLORIDE ION, Cisplatin, ... 著者 Tanley, S.W.M, Schreurs, A.M.M, Kroon-Batenburg, L.M.J, Helliwell, J.R. 登録日 2012-07-16 公開日 2012-11-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Room-temperature X-ray diffraction studies of cisplatin and carboplatin binding to His15 of HEWL after prolonged chemical exposure. Acta Crystallogr.,Sect.F, 68, 2012
4J19	Structure of a novel telomere repeat binding protein bound to DNA 分子名称: CHLORIDE ION, DNA (5'-D(*CP*TP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*GP*GP*GP*TP*TP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*CP*CP*TP*AP*AP*CP*A)-3'), ... 著者 Kappei, D, Butter, F, Benda, C, Scheibe, M, Draskovic, I, Stevense, M, Lopes Novo, C, Basquin, C, Krastev, D.B, Kittler, R, Jessberger, R, Londono-Vallejo, A.J, Mann, M, Buchholz, F. 登録日 2013-02-01 公開日 2013-05-29 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. Embo J., 32, 2013
4B4J	1.25 A Structure of Lysozyme Crystallized with (RS)-2-methyl-2,4- pentanediol 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, CHLORIDE ION, LYSOZYME C 著者 Jakoncic, J, Berger, J, Stauber, M, Axelbaum, A, Asherie, N. 登録日 2012-07-30 公開日 2012-08-22 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Crystallization of Lysozyme with (R)-, (S)- and (Rs)-2-Methyl-2,4-Pentanediol Acta Crystallogr.,Sect.D, 71, 2015
4B05	Preclinical characterization of AZD3839, a novel clinical candidate BACE1 inhibitor for the treatment of Alzheimer Disease 分子名称: (1S)-1-[2-(difluoromethyl)pyridin-4-yl]-4-fluoro-1-(3-pyrimidin-5-ylphenyl)-1H-isoindol-3-amine, ACETATE ION, BETA-SECRETASE 1, ... 著者 Jeppsson, F, Eketjall, S, Janson, J, Karlstrom, S, Gustavsson, S, Olsson, L.L, Radesater, A.C, Ploeger, B, Cebers, G, Kolmodin, K, Swahn, B.M, von Berg, S, Bueters, T, Falting, J. 登録日 2012-06-28 公開日 2012-10-17 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Discovery of AZD3839, a potent and selective BACE1 inhibitor clinical candidate for the treatment of Alzheimer disease. J. Biol. Chem., 287, 2012
3P5I	Structure of the carbohydrate-recognition domain of human Langerin with 6-SO4-Gal-GlcNAc 分子名称: 6-O-sulfo-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C-type lectin domain family 4 member K, CALCIUM ION 著者 Feinberg, H, Taylor, M.E, Razi, N, McBride, R, Knirel, Y.A, Graham, S.A, Drickamer, K, Weis, W.I. 登録日 2010-10-08 公開日 2010-12-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis for Langerin Recognition of Diverse Pathogen and Mammalian Glycans through a Single Binding Site. J.Mol.Biol., 405, 2011
3P5Q	Ferric R-state human aquomethemoglobin 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Yi, J, Thomas, L.M, Richter-Addo, G.B. 登録日 2010-10-10 公開日 2011-06-08 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of human R-state aquomethemoglobin at 2.0 A resolution Acta Crystallogr.,Sect.F, 67, 2011
1HEO	STRUCTURAL AND THERMODYNAMIC ANALYSIS OF COMPENSATING MUTATIONS WITHIN THE CORE OF CHICKEN EGG WHITE LYSOZYME 分子名称: HEN EGG WHITE LYSOZYME 著者 Wilson, K.P, Malcolm, B.A, Matthews, B.W. 登録日 1992-01-10 公開日 1993-10-31 最終更新日 2021-06-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and thermodynamic analysis of compensating mutations within the core of chicken egg white lysozyme. J.Biol.Chem., 267, 1992
1HEW	REFINEMENT OF AN ENZYME COMPLEX WITH INHIBITOR BOUND AT PARTIAL OCCUPANCY. HEN EGG-WHITE LYSOZYME AND TRI-N-ACETYLCHITOTRIOSE AT 1.75 ANGSTROMS RESOLUTION 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEN EGG WHITE LYSOZYME 著者 Cheetham, J.C, Artymiuk, P.J, Phillips, D.C. 登録日 1992-01-20 公開日 1994-01-31 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Refinement of an enzyme complex with inhibitor bound at partial occupancy. Hen egg-white lysozyme and tri-N-acetylchitotriose at 1.75 A resolution. J.Mol.Biol., 224, 1992
4G9A	Crystal structure of calcium2+-bound wild-type CD23 lectin domain 分子名称: CALCIUM ION, GLYCEROL, Low affinity immunoglobulin epsilon Fc receptor 著者 Yuan, D, Sutton, B.J, Dhaliwal, B. 登録日 2012-07-23 公開日 2013-06-26 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Ca2+-dependent Structural Changes in the B-cell Receptor CD23 Increase Its Affinity for Human Immunoglobulin E. J.Biol.Chem., 288, 2013
1HFZ	ALPHA-LACTALBUMIN 分子名称: ALPHA-LACTALBUMIN, CALCIUM ION 著者 Pike, A.C.W, Brew, K, Acharya, K.R. 登録日 1996-06-13 公開日 1997-07-29 最終更新日 2021-11-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structures of guinea-pig, goat and bovine alpha-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase. Structure, 4, 1996
4J17	CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-Cyano-pyridine-2-carboxylic acid [3-((S)-2-amino-4-difluoromethyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide 分子名称: Beta-secretase 1, DIMETHYL SULFOXIDE, N-{3-[(4S)-2-amino-4-(difluoromethyl)-5,6-dihydro-4H-1,3-oxazin-4-yl]-4-fluorophenyl}-5-cyanopyridine-2-carboxamide, ... 著者 Kuglstatter, A, Stihle, M. 登録日 2013-02-01 公開日 2013-05-01 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 beta-Secretase (BACE1) Inhibitors with High In Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer s Disease J.Med.Chem., 56, 2013
3P4Z	Time-dependent and Protein-directed In Situ Growth of Gold Nanoparticles in a Single Crystal of Lysozyme 分子名称: CHLORIDE ION, GOLD 3+ ION, GOLD ION, ... 著者 Wei, H, Wang, Z, Zhang, J, House, S, Gao, Y.-G, Yang, L, Robinson, H, Tan, L.H, Xing, H, Hou, C, Robertson, I.M, Zuo, J.-M, Lu, Y. 登録日 2010-10-07 公開日 2011-02-09 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme. Nat Nanotechnol, 6, 2011
4G8O	Crystal Structure of a novel small molecule inactivator bound to plasminogen activator inhibitor-1 分子名称: (2S)-3-({[3-(trifluoromethyl)phenoxy]carbonyl}amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate), 1,2-ETHANEDIOL, Plasminogen activator inhibitor 1, ... 著者 Stuckey, J.A, Lawrence, D.A, Li, S.-H. 登録日 2012-07-23 公開日 2013-12-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Mechanistic characterization and crystal structure of a small molecule inactivator bound to plasminogen activator inhibitor-1. Proc.Natl.Acad.Sci.USA, 110, 2013
7WZ6	Crystal structure of MyoD-E47 分子名称: Isoform E47 of Transcription factor E2-alpha, Myoblast determination protein 1 著者 Zhong, J, Huang, Y, Ma, J. 登録日 2022-02-17 公開日 2022-06-22 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structural basis of the bHLH domains of MyoD-E47 heterodimer. Biochem.Biophys.Res.Commun., 621, 2022
4GBY	The structure of the MFS (major facilitator superfamily) proton:xylose symporter XylE bound to D-xylose 分子名称: D-xylose-proton symporter, beta-D-xylopyranose, nonyl beta-D-glucopyranoside 著者 Sun, L.F, Zeng, X, Yan, C.Y, Yan, N. 登録日 2012-07-28 公開日 2012-10-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.808 Å) 主引用文献 Crystal structure of a bacterial homologue of glucose transporters GLUT1-4. Nature, 490, 2012
4IT7	Crystal structure of Al-CPI 分子名称: CPI 著者 Mei, G.Q, Liu, S.L, Sun, M.Z, Liu, J. 登録日 2013-01-17 公開日 2014-01-29 最終更新日 2014-06-11 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural Basis for the Immunomodulatory Function of Cysteine Protease Inhibitor from Human Roundworm Ascaris lumbricoides. Plos One, 9, 2014
4GCE	Room temperature X-ray diffraction study of a 6-fold molar excess of a cisplatin/carboplatin mixture binding to HEWL, Dataset 3 分子名称: Cisplatin, DIMETHYL SULFOXIDE, Lysozyme C 著者 Helliwell, J.R, Tanley, S.W.M. 登録日 2012-07-30 公開日 2013-01-02 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 The crystal structure analysis of the relative binding of cisplatin and carboplatin in a mixture with histidine in a protein studied at 100 and 300 K with repeated X-ray irradiation. Acta Crystallogr.,Sect.D, 69, 2013
7WZ8	Structure of human langerin complex in Birbeck granules 分子名称: SNAP-tag,C-type lectin domain family 4 member K 著者 Oda, T, Yanagisawa, H. 登録日 2022-02-17 公開日 2022-06-22 最終更新日 2023-08-02 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Cryo-electron tomography of Birbeck granules reveals the molecular mechanism of langerin lattice formation. Elife, 11, 2022
3P6W	Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC3-Etg-Boc 分子名称: Camphor 5-monooxygenase, PROTOPORPHYRIN IX CONTAINING FE 著者 Lee, Y.-T, Wilson, R.F, Glazer, E.C, Goodin, D.B. 登録日 2010-10-11 公開日 2010-11-17 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal Structure of Cytochrome P450cam crystallized in the presence of a tethered substrate analog AdaC3-Etg-Boc To be Published
4FSE	crystal structure of beta-site app-cleaving enzyme 1 (bace-wt) complex with N-(N-(4-amino-3,5- dichlorobenzyl)carbamimidoyl)-3-(4-methoxyphenyl)-5- methyl-4-isothiazolecarboxamide 分子名称: Beta-secretase 1, IODIDE ION, N-[N-(4-amino-3,5-dichlorobenzyl)carbamimidoyl]-3-(4-methoxyphenyl)-5-methyl-1,2-thiazole-4-carboxamide 著者 Muckelbauer, J.K. 登録日 2012-06-27 公開日 2012-10-10 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Acyl guanidine inhibitors of beta-secretase (BACE-1): optimization of a micromolar hit to a nanomolar lead via iterative solid- and solution-phase library synthesis J.Med.Chem., 55, 2012
3P49	Crystal Structure of a Glycine Riboswitch from Fusobacterium nucleatum 分子名称: GLYCINE, GLYCINE RIBOSWITCH, MAGNESIUM ION, ... 著者 Butler, E.B, Wang, J, Xiong, Y, Strobel, S. 登録日 2010-10-06 公開日 2011-04-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.55 Å) 主引用文献 Structural basis of cooperative ligand binding by the glycine riboswitch. Chem.Biol., 18, 2011
4BAF	Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethyltriazoledipicolinate complex at 1.51 A resolution. 分子名称: 4-(4-(2-hydroxyethyl)-1H-1,2,3-triazol-1-yl)pyridine-2,6-dicarboxylic acid, ACETATE ION, CHLORIDE ION, ... 著者 Talon, R, Kahn, R, Gautier, A, Nauton, L, Girard, E. 登録日 2012-09-14 公開日 2012-11-14 最終更新日 2019-03-06 実験手法 X-RAY DIFFRACTION (1.507 Å) 主引用文献 Clicked Europium Dipicolinate Complexes for Protein X-Ray Structure Determination. Chem.Commun.(Camb.), 48, 2012
3P5D	Structure of the carbohydrate-recognition domain of human Langerin with man5 (Man alpha1-3(Man alpha1-6)Man alpha1-6)(Man- alpha1-3)Man 分子名称: C-type lectin domain family 4 member K, CALCIUM ION, alpha-D-mannopyranose, ... 著者 Feinberg, H, Taylor, M.E, Razi, N, McBride, R, Knirel, Y.A, Graham, S.A, Drickamer, K, Weis, W.I. 登録日 2010-10-08 公開日 2010-12-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.8013 Å) 主引用文献 Structural Basis for Langerin Recognition of Diverse Pathogen and Mammalian Glycans through a Single Binding Site. J.Mol.Biol., 405, 2011
1HYL	THE 1.8 A STRUCTURE OF COLLAGENASE FROM HYPODERMA LINEATUM 分子名称: HYPODERMA LINEATUM COLLAGENASE 著者 Broutin, I, Arnoux, B, Riche, C, Lecroisey, A, Keil, B, Pascard, C, Ducruix, A. 登録日 1995-05-02 公開日 1995-07-31 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 1.8 A structure of Hypoderma lineatum collagenase: a member of the serine proteinase family. Acta Crystallogr.,Sect.D, 52, 1996

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