2FAK
 
 | | Crystal structure of Salinosporamide A in complex with the yeast 20S proteasome | | 分子名称: | (3AR,6R,6AS)-6-((S)-((S)-CYCLOHEX-2-ENYL)(HYDROXY)METHYL)-6A-METHYL-4-OXO-HEXAHYDRO-2H-FURO[3,2-C]PYRROLE-6-CARBALDEHYDE, Proteasome component C1, Proteasome component C11, ... | | 著者 | Groll, M, Potts, B.C. | | 登録日 | 2005-12-07 | | 公開日 | 2006-04-18 | | 最終更新日 | 2023-05-31 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal Structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in Complex with the 20S Proteasome Reveal Important Consequences of beta-Lactone Ring Opening and a Mechanism for Irreversible Binding.
J.Am.Chem.Soc., 128, 2006
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2QA3
 | | Structural Studies Reveal the Inactivation of E. coli L-aspartate aminotransferase by (S)-4,5-amino-dihydro-2-thiophenecarboxylic acid (SADTA) via two mechanisms (at pH6.5) | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, Aspartate aminotransferase, ... | | 著者 | Liu, D, Pozharski, E, Lepore, B, Fu, M, Silverman, R.B, Petsko, G.A, Ringe, D. | | 登録日 | 2007-06-14 | | 公開日 | 2007-12-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals "a tale of two mechanisms".
Biochemistry, 46, 2007
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2QZ8
 | | Crystal structure of Mycobacterium tuberculosis Leucine response regulatory protein (LrpA) | | 分子名称: | Probable transcriptional regulatory protein | | 著者 | Manchi, C.M.R, Gokulan, K, Ioerger, T, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2007-08-16 | | 公開日 | 2007-11-06 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | Crystal structure of Mycobacterium tuberculosis LrpA, a leucine-responsive global regulator associated with starvation response.
Protein Sci., 17, 2008
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2O3L
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2F8I
 | | Human transthyretin (TTR) complexed with Benzoxazole | | 分子名称: | 2-(2,6-DICHLOROPHENYL)-1,3-BENZOXAZOLE-6-CARBOXYLIC ACID, Transthyretin | | 著者 | Palaninathan, S.K, Mohamedmohaideen, N.N, Sacchettini, J.C, Kelly, J.W. | | 登録日 | 2005-12-02 | | 公開日 | 2005-12-20 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.541 Å) | | 主引用文献 | Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis, evaluation, and mechanism of action
Angew.Chem.Int.Ed.Engl., 42, 2003
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2OLR
 | | Crystal structure of Escherichia coli phosphoenolpyruvate carboxykinase complexed with carbon dioxide, Mg2+, ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, CARBON DIOXIDE, CHLORIDE ION, ... | | 著者 | Cotelesage, J.J, Delbaere, L.T, Goldie, H, Puttick, J, Rajabi, B, Novakovski, B. | | 登録日 | 2007-01-19 | | 公開日 | 2007-06-12 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | How does an enzyme recognize CO2?
Int.J.Biochem.Cell Biol., 39, 2007
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2FDV
 | | Microsomal P450 2A6 with the inhibitor N-Methyl(5-(pyridin-3-yl)furan-2-yl)methanamine bound | | 分子名称: | 1,2-ETHANEDIOL, Cytochrome P450 2A6, N-METHYL(5-(PYRIDIN-3-YL)FURAN-2-YL)METHANAMINE, ... | | 著者 | Yano, J.K, Stout, C.D, Johnson, E.F. | | 登録日 | 2005-12-14 | | 公開日 | 2006-11-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization.
J.Med.Chem., 49, 2006
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2FHZ
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2OLO
 | | NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: open form at 1.9A resolution | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, FLAVIN-ADENINE DINUCLEOTIDE, PYRIDINE-2-CARBOXYLIC ACID, ... | | 著者 | Carrell, C.J, Bruckner, R.C, Venci, D, Zhao, G, Jorns, M.S, Mathews, F.S. | | 登録日 | 2007-01-19 | | 公開日 | 2007-07-31 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | NikD, an unusual amino acid oxidase essential for nikkomycin biosynthesis: structures of closed and open forms at 1.15 and 1.90 A resolution
Structure, 15, 2007
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2FK0
 | | Crystal Structure of a H5N1 influenza virus hemagglutinin. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin | | 著者 | Stevens, J, Wilson, I.A. | | 登録日 | 2006-01-03 | | 公開日 | 2006-05-02 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | Structure and Receptor Specificity of the Hemagglutinin from an H5N1 Influenza Virus.
Science, 312, 2006
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2F2G
 | | X-Ray Structure of Gene Product From Arabidopsis Thaliana AT3G16990 | | 分子名称: | 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE, SEED MATURATION PROTEIN PM36 HOMOLOG, SULFATE ION | | 著者 | Wesenberg, G.W, Smith, D.W, Phillips Jr, G.N, Johnson, K.A, Bitto, E, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2005-11-16 | | 公開日 | 2005-12-13 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of gene locus At3g16990 from Arabidopsis thaliana
Proteins, 57, 2004
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2QA4
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2FDY
 | | Microsomal P450 2A6 with the inhibitor Adrithiol bound | | 分子名称: | 4,4'-DIPYRIDYL DISULFIDE, Cytochrome P450 2A6, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Yano, J.K, Stout, C.D, Johnson, E.F. | | 登録日 | 2005-12-14 | | 公開日 | 2006-11-28 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Synthetic Inhibitors of Cytochrome P-450 2A6: Inhibitory Activity, Difference Spectra, Mechanism of Inhibition, and Protein Cocrystallization.
J.Med.Chem., 49, 2006
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2QNC
 | | Crystal structure of T4 Endonuclease VII N62D mutant in complex with a DNA Holliday junction | | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*DAP*DGP*DGP*DCP*DCP*DTP*DAP*DGP*DCP*DGP*DTP*DCP*DCP*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DTP*DTP*DCP*DG)-3'), DNA (5'-D(*DCP*DAP*DCP*DAP*DTP*DCP*DGP*DAP*DTP*DGP*DGP*DAP*DGP*DCP*DCP*DGP*DCP*DTP*DAP*DGP*DGP*DCP*DCP*DT)-3'), ... | | 著者 | Biertumpfel, C, Yang, W, Suck, D. | | 登録日 | 2007-07-18 | | 公開日 | 2008-01-29 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of T4 endonuclease VII resolving a Holliday junction.
Nature, 449, 2007
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2CCA
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2CFE
 | | The 1.5 A crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family | | 分子名称: | ALANINE, ALLERGEN, GLYCEROL, ... | | 著者 | Limacher, A, Glaser, A.G, Fluckiger, S, Scheynius, A, Scapozza, L, Crameri, R. | | 登録日 | 2006-02-20 | | 公開日 | 2006-02-22 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Analysis of the cross-reactivity and of the 1.5 A crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family.
Biochem. J., 396, 2006
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2QDW
 | | Structure of Cu(I) form of the M51A mutant of amicyanin | | 分子名称: | Amicyanin, COPPER (I) ION, PHOSPHATE ION | | 著者 | Ma, J.K, Wang, Y, Carrell, C.J, Mathews, F.S, Davidson, V.L. | | 登録日 | 2007-06-21 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (0.92 Å) | | 主引用文献 | A single methionine residue dictates the kinetic mechanism of interprotein electron transfer from methylamine dehydrogenase to amicyanin.
Biochemistry, 46, 2007
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2QEG
 | | B-DNA with 7-deaza-dG modification | | 分子名称: | DNA (5'-D(*DCP*DGP*DCP*DGP*DAP*DAP*DTP*DTP*DCP*(7GU)P*DCP*DG)-3') | | 著者 | Wang, F, Li, F, Ganguly, M, Marky, L.A, Gold, B, Egli, M, Stone, M.P. | | 登録日 | 2007-06-25 | | 公開日 | 2008-05-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards.
Biochemistry, 47, 2008
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2QDV
 | | Structure of the Cu(II) form of the M51A mutant of amicyanin | | 分子名称: | Amicyanin, COPPER (II) ION, PHOSPHATE ION | | 著者 | Carrell, C.J, Ma, J.K, Wang, Y, Davidson, V.L, Mathews, F.S. | | 登録日 | 2007-06-21 | | 公開日 | 2007-12-11 | | 最終更新日 | 2021-10-20 | | 実験手法 | X-RAY DIFFRACTION (0.89 Å) | | 主引用文献 | A single methionine residue dictates the kinetic mechanism of interprotein electron transfer from methylamine dehydrogenase to amicyanin.
Biochemistry, 46, 2007
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2QF2
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2QMC
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2F4V
 | | 30S ribosome + designer antibiotic | | 分子名称: | (2R)-4-AMINO-N-{(1R,2S,3R,4R,5S)-5-AMINO-2-{2-[(2-AMINOETHYL)AMINO]ETHOXY}-4-[(2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-3-HYDROXYCYCLOHEXYL}-2-HYDROXYBUTANAMIDE, (2S,4S,4AR,5AS,6S,11R,11AS,12R,12AR)-7-CHLORO-4-(DIMETHYLAMINO)-6,10,11,12-TETRAHYDROXY-1,3-DIOXO-1,2,3,4,4A,5,5A,6,11,11A,12,12A-DODECAHYDROTETRACENE-2-CARBOXAMIDE, 16S ribosomal RNA, ... | | 著者 | Murray, J.B, Meroueh, S.O, Russell, R.J, Lentzen, G, Haddad, J, Mobashery, S. | | 登録日 | 2005-11-24 | | 公開日 | 2006-07-04 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | | 主引用文献 | Interactions of designer antibiotics and the bacterial ribosome aminoacyl-tRNA site
Chem.Biol., 13, 2006
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2R4V
 | | Structure of human CLIC2, crystal form A | | 分子名称: | Chloride intracellular channel protein 2, GLUTATHIONE | | 著者 | Hansen, G, Cromer, B.A, Gorman, M.A, Parker, M.W. | | 登録日 | 2007-09-02 | | 公開日 | 2007-11-13 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure of the Janus Protein Human CLIC2
J.Mol.Biol., 374, 2007
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2DUE
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2DF7
 | | Crystal structure of infectious bursal disease virus VP2 subviral particle | | 分子名称: | CALCIUM ION, CHLORIDE ION, structural polyprotein VP2 | | 著者 | Ko, T.P, Lee, C.C, Wang, M.Y, Wang, A.H. | | 登録日 | 2006-02-27 | | 公開日 | 2006-06-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of infectious bursal disease virus VP2 subviral particle at 2.6A resolution: Implications in virion assembly and immunogenicity.
J.Struct.Biol., 155, 2006
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