2YEU
 
 | | Structural and functional insights of DR2231 protein, the MazG-like nucleoside triphosphate pyrophosphohydrolase from Deinococcus radiodurans, complex with Gd | | 分子名称: | DR2231, GADOLINIUM ATOM, GLYCEROL, ... | | 著者 | Goncalves, A.M.D, de Sanctis, D, McSweeney, S.M. | | 登録日 | 2011-03-30 | | 公開日 | 2011-07-06 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Functional Insights Into Dr2231 Protein, the Mazg-Like Nucleoside Triphosphate Pyrophosphohydrolase from Deinococcus Radiodurans.
J.Biol.Chem., 286, 2011
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4R3E
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3B54
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9L5T
 | | Cryo-EM structure of the thermophile spliceosome (state B*Q2) | | 分子名称: | Anaphase-promoting complex subunit 4-like WD40 domain-containing protein, CCDC12, Delta(14)-sterol reductase, ... | | 著者 | Li, Y, Fischer, P, Wang, M, Yuan, R, Meng, W, Luehrmann, R, Lau, B, Hurt, E, Cheng, J. | | 登録日 | 2024-12-23 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-04-16 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structural insights into spliceosome fidelity: DHX35-GPATCH1- mediated rejection of aberrant splicing substrates.
Cell Res., 35, 2025
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9L5S
 | | Cryo-EM structure of the thermophile spliceosome (state B*Q1) | | 分子名称: | Anaphase-promoting complex subunit 4-like WD40 domain-containing protein, CCDC12, Delta(14)-sterol reductase, ... | | 著者 | Li, Y, Fischer, P, Wang, M, Yuan, R, Meng, W, Luehrmann, R, Lau, B, Hurt, E, Cheng, J. | | 登録日 | 2024-12-23 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-04-16 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural insights into spliceosome fidelity: DHX35-GPATCH1- mediated rejection of aberrant splicing substrates.
Cell Res., 35, 2025
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9L5R
 | | Cryo-EM structure of the thermophile spliceosome (state ILS) | | 分子名称: | Anaphase-promoting complex subunit 4-like WD40 domain-containing protein, CCDC12, Cell cycle control protein, ... | | 著者 | Li, Y, Fischer, P, Wang, M, Yuan, R, Meng, W, Luehrmann, R, Lau, B, Hurt, E, Cheng, J. | | 登録日 | 2024-12-23 | | 公開日 | 2025-03-12 | | 最終更新日 | 2025-04-16 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural insights into spliceosome fidelity: DHX35-GPATCH1- mediated rejection of aberrant splicing substrates.
Cell Res., 35, 2025
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7EYK
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7EYP
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7EYJ
 | | Crystal structure of Escherichia coli ppnP | | 分子名称: | Pyrimidine/purine nucleoside phosphorylase, SULFATE ION | | 著者 | Wen, Y, Wu, B.X. | | 登録日 | 2021-05-31 | | 公開日 | 2022-02-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Crystal structures of a new class of pyrimidine/purine nucleoside phosphorylase revealed a Cupin fold.
Proteins, 90, 2022
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7EYL
 | | Crystal structure of Salmonella enterica ppnP | | 分子名称: | Pyrimidine/purine nucleoside phosphorylase | | 著者 | Wen, Y, Wu, B.X. | | 登録日 | 2021-05-31 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal structures of a new class of pyrimidine/purine nucleoside phosphorylase revealed a Cupin fold.
Proteins, 90, 2022
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7EYM
 | | Crystal structure of Vibrio cholerae ppnP | | 分子名称: | Pyrimidine/purine nucleoside phosphorylase | | 著者 | Wen, Y, Wu, B.X. | | 登録日 | 2021-05-31 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | | 主引用文献 | Crystal structures of a new class of pyrimidine/purine nucleoside phosphorylase revealed a Cupin fold.
Proteins, 90, 2022
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4R9X
 | | Crystal Structure of Putative Copper Homeostasis Protein CutC from Bacillus anthracis | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, Copper homeostasis protein CutC, ... | | 著者 | Kim, Y, Zhou, M, Makowska-Grzyska, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, CSGID, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2014-09-08 | | 公開日 | 2014-09-17 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.8515 Å) | | 主引用文献 | Crystal Structure of Putative Copper Homeostasis Protein CutC
from Bacillus anthracis
To be Published, 2014
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8F5X
 | | Crystal structure of human eosinophil-derived neurotoxin (EDN, ribonuclease 2) in complex with 5'-adenosine monophosphate (AMP) | | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE MONOPHOSPHATE, Non-secretory ribonuclease, ... | | 著者 | Tran, T.T.Q, Pham, N.T.H, Calmettes, C, Doucet, N. | | 登録日 | 2022-11-15 | | 公開日 | 2023-11-29 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Ancestral sequence reconstruction dissects structural and functional differences among eosinophil ribonucleases.
J.Biol.Chem., 300, 2024
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8FU3
 | | Structure Of Respiratory Syncytial Virus Polymerase with Novel Non-Nucleoside Inhibitor | | 分子名称: | 8-methoxy-3-methyl-N-{(2S)-3,3,3-trifluoro-2-[5-fluoro-6-(4-fluorophenyl)-4-(2-hydroxypropan-2-yl)pyridin-2-yl]-2-hydroxypropyl}cinnoline-6-carboxamide, Phosphoprotein, RNA-directed RNA polymerase L | | 著者 | Yu, X, Abeywickrema, P, Bonneux, B, Behera, I, Jacoby, E, Fung, A, Adhikary, S, Bhaumik, A, Carbajo, R.J, Bruyn, S.D, Miller, R, Patrick, A, Pham, Q, Piassek, M, Verheyen, N, Shareef, A, Sutto-Ortiz, P, Ysebaert, N, Vlijmen, H.V, Jonckers, T.H.M, Herschke, F, McLellan, J.S, Decroly, E, Fearns, R, Grosse, S, Roymans, D, Sharma, S, Rigaux, P, Jin, Z. | | 登録日 | 2023-01-16 | | 公開日 | 2023-11-01 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Structural and mechanistic insights into the inhibition of respiratory syncytial virus polymerase by a non-nucleoside inhibitor.
Commun Biol, 6, 2023
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6LD2
 | | Zika NS5 polymerase domain | | 分子名称: | (1S,2S,4S,5R)-2,4-dimethoxy-5-thiophen-2-yl-cyclohexane-1-carboxylic acid, RNA-directed RNA polymerase NS5, ZINC ION | | 著者 | El Sahili, A, Lescar, J. | | 登録日 | 2019-11-20 | | 公開日 | 2020-08-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
J.Virol., 94, 2020
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6LD1
 | | Zika NS5 polymerase domain | | 分子名称: | 1,2-ETHANEDIOL, RNA-directed RNA polymerase NS5, ZINC ION | | 著者 | El Sahili, A, Lescar, J. | | 登録日 | 2019-11-20 | | 公開日 | 2020-08-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
J.Virol., 94, 2020
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9MH2
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6LD5
 | | Zika NS5 polymerase domain | | 分子名称: | 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid, RNA-directed RNA polymerase NS5, ZINC ION, ... | | 著者 | El Sahili, A, Lescar, J. | | 登録日 | 2019-11-20 | | 公開日 | 2020-08-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
J.Virol., 94, 2020
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6LD4
 | | Zika NS5 polymerase domain | | 分子名称: | 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid, 3-methoxybenzenesulfonamide, RNA-directed RNA polymerase NS5, ... | | 著者 | El Sahili, A, Lescar, J. | | 登録日 | 2019-11-20 | | 公開日 | 2020-08-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
J.Virol., 94, 2020
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6LD3
 | | Zika NS5 polymerase domain | | 分子名称: | 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid, RNA-directed RNA polymerase NS5, ZINC ION, ... | | 著者 | El Sahili, A, Lescar, J. | | 登録日 | 2019-11-20 | | 公開日 | 2020-08-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Non-nucleoside Inhibitors of Zika Virus RNA-Dependent RNA Polymerase.
J.Virol., 94, 2020
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7U30
 | | PRMT5:MEP50 Complexed with Cyclonucleoside Compound 1 | | 分子名称: | (9R,10R,11S,12R,13R,14R)-4-amino-9-(3,4-difluorophenyl)-6,7,8,9,10,11,12,13-octahydro-10,13-epoxy[1,3]diazecino[1,2-e]purine-11,12-diol, 1,2-ETHANEDIOL, Methylosome protein 50, ... | | 著者 | Palte, R.L. | | 登録日 | 2022-02-25 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Design and synthesis of unprecedented 9- and 10-membered cyclonucleosides with PRMT5 inhibitory activity.
Bioorg.Med.Chem., 66, 2022
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3V9B
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8RPS
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8RPT
 | | Crystal structure of human DNPH1 mutant- D80A | | 分子名称: | 1,2-ETHANEDIOL, 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, CHLORIDE ION, ... | | 著者 | Devi, S, da Silva, R.G. | | 登録日 | 2024-01-17 | | 公開日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Human 2'-Deoxynucleoside 5'-Phosphate N-Hydrolase 1: The Catalytic Roles of Tyr24 and Asp80.
Chembiochem, 25, 2024
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8RQD
 | | Crystal structure of human DNPH1 mutant-Y24F | | 分子名称: | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Devi, S, da Silva, R.G. | | 登録日 | 2024-01-17 | | 公開日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Human 2'-Deoxynucleoside 5'-Phosphate N-Hydrolase 1: The Catalytic Roles of Tyr24 and Asp80.
Chembiochem, 25, 2024
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