PDB: 66507 件ウェブページステータス検索Chemie searchBIRD

---

5Z7Y	Crystal structure of Striga hermonthica HTL7 (ShHTL7) 分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, Hyposensitive to light 7, ... 著者 Xu, Y, Miyakawa, T, Nakamura, A, Tanokura, M. 登録日 2018-01-30 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural analysis of HTL and D14 proteins reveals the basis for ligand selectivity in Striga. Nat Commun, 9, 2018
4ETD	Lysozyme, room-temperature, rotating anode, 0.0026 MGy 分子名称: CHLORIDE ION, Lysozyme C 著者 Boutet, S, Lomb, L, Williams, G, Barends, T, Aquila, A, Doak, R.B, Weierstall, U, DePonte, D, Steinbrener, J, Shoeman, R, Messerschmidt, M, Barty, A, White, T, Kassemeyer, S, Kirian, R, Seibert, M, Montanez, P, Kenney, C, Herbst, R, Hart, P, Pines, J, Haller, G, Gruner, S, Philllip, H, Tate, M, Hromalik, M, Koerner, L, van Bakel, N, Morse, J, Ghonsalves, W, Arnlund, D, Bogan, M, Calemann, C, Fromme, R, Hampton, C, Hunter, M, Johansson, L, Katona, G, Kupitz, C, Liang, M, Martin, A, Nass, K, Redecke, L, Stellato, F, Timneanu, N, Wang, D, Zatsepin, N, Schafer, D, Defever, K, Neutze, R, Fromme, P, Spence, J, Chapman, H, Schlichting, I. 登録日 2012-04-24 公開日 2012-06-13 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (1.904 Å) 主引用文献 High-resolution protein structure determination by serial femtosecond crystallography. Science, 337, 2012
1ZIX	Crystal Structure Analysis of the dienelactone hydrolase mutant (E36D, R105H, C123S, G211D, K234N)- 1.8 A 分子名称: Carboxymethylenebutenolidase, GLYCEROL 著者 Kim, H.-K, Liu, J.-W, Carr, P.D, Ollis, D.L. 登録日 2005-04-27 公開日 2005-07-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Following directed evolution with crystallography: structural changes observed in changing the substrate specificity of dienelactone hydrolase. Acta Crystallogr.,Sect.D, 61, 2005
6G69	Crystal structure of a parallel seven-helix coiled coil CC-Type2-IL-Sg-L17E 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, CC-Type2-IL-Sg-L17E 著者 Rhys, G.G, Brady, R.L, Woolfson, D.N. 登録日 2018-04-01 公開日 2018-10-17 最終更新日 2019-01-23 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Maintaining and breaking symmetry in homomeric coiled-coil assemblies. Nat Commun, 9, 2018
5J13	Structural basis for TSLP antagonism by the therapeutic antibody Tezepelumab (MEDI9929 / AMG-157) 分子名称: SULFATE ION, Thymic stromal lymphopoietin, anti-TSLP Fab-fragment, ... 著者 Verstraete, K, Savvides, S.N. 登録日 2016-03-28 公開日 2017-04-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.298 Å) 主引用文献 Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma. Nat Commun, 8, 2017
5JQN	NitN Amidase from Neterenkonia sp. AN1 after thrombin His-tag removal. 分子名称: Aliphatic amidase 著者 Sewell, B.T, Kimani, S.W, Weber, B.W. 登録日 2016-05-05 公開日 2016-05-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.19 Å) 主引用文献 QM/MM Modelling of Substrate Binding in the Amidase Active Site To Be Published
2P93	Factor xa in complex with the inhibitor 5-chloro-N-(2-(4-(2-oxopyridin-1(2H)-yl)benzamido)ethyl)thiophene-2-carboxamide 分子名称: 5-CHLORO-N-(2-(4-(2-OXOPYRIDIN-1(2H)-YL)BENZAMIDO)ETHYL)THIOPHENE-2-CARBOXAMIDE, Factor Xa 著者 Chang, C.-H. 登録日 2007-03-23 公開日 2007-07-24 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 SAR and X-ray structures of enantiopure 1,2-cis-(1R,2S)-cyclopentyldiamine and cyclohexyldiamine derivatives as inhibitors of coagulation Factor Xa Bioorg.Med.Chem.Lett., 17, 2007
5JPM	Structure of the complex of human complement C4 with MASP-2 rebuilt using iMDFF 分子名称: Complement C4-A, Mannan-binding lectin serine protease 2, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Croll, T.I, Andersen, G.R. 登録日 2016-05-03 公開日 2016-08-10 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.75 Å) 主引用文献 Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4. Acta Crystallogr D Struct Biol, 72, 2016
4ENX	Crystal Structure of Pim-1 Kinase in complex with inhibitor (2E,5Z)-2-(2-chlorophenylimino)-5-(4-hydroxy-3-nitrobenzylidene)thiazolidin-4-one 分子名称: (2Z,5Z)-2-[(2-chlorophenyl)imino]-5-(4-hydroxy-3-nitrobenzylidene)-1,3-thiazolidin-4-one, PHOSPHATE ION, Serine/threonine-protein kinase pim-1 著者 Parker, L.J, Handa, N, Yokoyama, S. 登録日 2012-04-13 公開日 2012-08-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Flexibility of the P-loop of Pim-1 kinase: observation of a novel conformation induced by interaction with an inhibitor Acta Crystallogr.,Sect.F, 68, 2012
4CGU	Full length Tah1 bound to yeast PIH1 and HSP90 peptide SRMEEVD 分子名称: GLYCEROL, HEAT SHOCK PROTEIN HSP 90-ALPHA, PROTEIN INTERACTING WITH HSP90 1, ... 著者 Roe, S.M, Pal, M. 登録日 2013-11-26 公開日 2014-05-14 最終更新日 2017-06-28 実験手法 X-RAY DIFFRACTION (2.11 Å) 主引用文献 Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1. Structure, 22, 2014
7URG	cryo-EM structure of ribonucleotide reductase from Synechococcus phage S-CBP4 bound with TTP 分子名称: Ribonucleotide reductase, THYMIDINE-5'-TRIPHOSPHATE 著者 Xu, D, Burnim, A.A, Ando, N. 登録日 2022-04-21 公開日 2022-09-07 最終更新日 2022-10-05 実験手法 ELECTRON MICROSCOPY (3.46 Å) 主引用文献 Comprehensive phylogenetic analysis of the ribonucleotide reductase family reveals an ancestral clade. Elife, 11, 2022
5JTW	Crystal structure of complement C4b re-refined using iMDFF 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C4-A 著者 Croll, T.I, Andersen, G.R. 登録日 2016-05-09 公開日 2016-08-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4. Acta Crystallogr D Struct Biol, 72, 2016
6FKS	Crystal structure of a dye-decolorizing peroxidase from Klebsiella pneumoniae (KpDyP) 分子名称: GLYCEROL, Iron-dependent peroxidase, MAGNESIUM ION, ... 著者 Pfanzagl, V, Hofbauer, S, Mlynek, G. 登録日 2018-01-24 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.60000467 Å) 主引用文献 Roles of distal aspartate and arginine of B-class dye-decolorizing peroxidase in heterolytic hydrogen peroxide cleavage. J. Biol. Chem., 293, 2018
6FL2	Crystal structure of a dye-decolorizing peroxidase D143A variant from Klebsiella pneumoniae (KpDyP) 分子名称: GLYCEROL, Iron-dependent peroxidase, MAGNESIUM ION, ... 著者 Pfanzagl, V, Hofbauer, S, Mlynek, G. 登録日 2018-01-25 公開日 2018-08-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.270001 Å) 主引用文献 Roles of distal aspartate and arginine of B-class dye-decolorizing peroxidase in heterolytic hydrogen peroxide cleavage. J. Biol. Chem., 293, 2018
2ONY	Structure of hPNMT with inhibitor 7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy 分子名称: N-(4-CHLOROPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-7-SULFONAMIDE, PHOSPHATE ION, Phenylethanolamine N-methyltransferase, ... 著者 Drinkwater, N, Martin, J.L. 登録日 2007-01-24 公開日 2007-10-09 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Enzyme Adaptation to Inhibitor Binding: A Cryptic Binding Site in Phenylethanolamine N-Methyltransferase J.Med.Chem., 50, 2007
4DED	Aurora A in complex with YL1-038-21 分子名称: 1,2-ETHANEDIOL, 2-({2-[(4-carbamoylphenyl)amino]pyrimidin-4-yl}amino)benzamide, Aurora kinase A 著者 Martin, M.P, Zhu, J.-Y, Schonbrunn, E. 登録日 2012-01-20 公開日 2012-08-22 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Development of o-Chlorophenyl Substituted Pyrimidines as Exceptionally Potent Aurora Kinase Inhibitors. J.Med.Chem., 55, 2012
2OR3	Pre-oxidation Complex of Human DJ-1 分子名称: Protein DJ-1, SULFATE ION 著者 Witt, A.C, Lakshminarasimhan, M, Wilson, M.A. 登録日 2007-02-01 公開日 2007-02-13 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Cysteine pKa depression by a protonated glutamic acid in human DJ-1. Biochemistry, 47, 2008
4DCD	1.6A resolution structure of PolioVirus 3C Protease Containing a covalently bound dipeptidyl inhibitor 分子名称: (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Genome polyprotein, ... 著者 Lovell, S, Battaile, K.P, Kim, Y, Tiew, K.-C, Mandadapu, S.R, Alliston, K.R, Groutas, W.C, Chang, K.O. 登録日 2012-01-17 公開日 2012-09-05 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Broad-Spectrum Antivirals against 3C or 3C-Like Proteases of Picornaviruses, Noroviruses, and Coronaviruses. J.Virol., 86, 2012
5Z7W	Crystal structure of Striga hermonthica HTL1 (ShHTL1) 分子名称: GLYCEROL, Hyposensitive to light 1, MAGNESIUM ION, ... 著者 Xu, Y, Miyakawa, T, Nakamura, A, Tanokura, M. 登録日 2018-01-30 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.657 Å) 主引用文献 Structural analysis of HTL and D14 proteins reveals the basis for ligand selectivity in Striga. Nat Commun, 9, 2018
5JPN	Structure of human complement C4 rebuilt using iMDFF 分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C4-A, ... 著者 Croll, T.I, Andersen, G.R. 登録日 2016-05-03 公開日 2016-08-10 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Re-evaluation of low-resolution crystal structures via interactive molecular-dynamics flexible fitting (iMDFF): a case study in complement C4. Acta Crystallogr D Struct Biol, 72, 2016
1Y20	Crystal structure of the NR1 ligand-binding core in complex with ACPC 分子名称: 1-AMINOCYCLOPROPANECARBOXYLIC ACID, Glutamate [NMDA] receptor subunit zeta 1 著者 Inanobe, A, Gouaux, E. 登録日 2004-11-19 公開日 2005-07-12 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors. Neuron, 47, 2005
5YU9	Crystal structure of EGFR 696-1022 T790M in complex with Ibrutinib 分子名称: 1-{(3R)-3-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one, CHLORIDE ION, Epidermal growth factor receptor 著者 Yan, X.E, Yun, C.H. 登録日 2017-11-21 公開日 2017-12-27 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation. Oncotarget, 7, 2016
4DN3	Crystal structure of anti-mcp-1 antibody cnto888 分子名称: CNTO888 HEAVY CHAIN, CNTO888 LIGHT CHAIN 著者 Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G. 登録日 2012-02-08 公開日 2012-10-03 最終更新日 2018-01-24 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888. Mol.Immunol., 51, 2012
1Y1M	Crystal structure of the NR1 ligand binding core in complex with cycloleucine 分子名称: 1-AMINOCYCLOPENTANECARBOXYLIC ACID, Glutamate [NMDA] receptor subunit zeta 1 著者 Inanobe, A, Gouaux, E. 登録日 2004-11-18 公開日 2005-07-12 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors. Neuron, 47, 2005
1Y1Z	Crystal structure of the NR1 ligand binding core in complex with ACBC 分子名称: 1-AMINOCYCLOBUTANECARBOXLIC ACID, Glutamate [NMDA] receptor subunit zeta 1 著者 Inanobe, A, Gouaux, E. 登録日 2004-11-19 公開日 2005-07-12 最終更新日 2017-07-26 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors. Neuron, 47, 2005

<600601602603604605606607608609610611612613614615>