PDB: 35140 件ウェブページステータス検索Chemie searchBIRD

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8GCX	XFEL structure of Mycobacterium tuberculosis beta lactamase microcrystals mixed with sulbactam for 700 ms 分子名称: Beta-lactamase, PHOSPHATE ION, TRANS-ENAMINE INTERMEDIATE OF SULBACTAM 著者 Malla, T.N, Schmidt, M. 登録日 2023-03-03 公開日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Heterogeneity in M. tuberculosis beta-lactamase inhibition by Sulbactam. Nat Commun, 14, 2023
8GS3	Cryo-EM structure of human Neuroligin 3 分子名称: Neuroligin-3 著者 Zhang, H, Zhang, Z, Hou, M. 登録日 2022-09-04 公開日 2023-09-20 最終更新日 2024-04-03 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders. Front Endocrinol, 13, 2022
8G96	Adenylation domain structure from NRPS-like Delta-Poly-L-Ornithine synthetase (L-Ornithine bound) 分子名称: Dimodular nonribosomal peptide synthase, GLYCEROL, L-ornithine 著者 Patel, K.D, Gulick, A.M. 登録日 2023-02-21 公開日 2023-10-04 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural and functional insights into delta-poly-L-ornithine polymer biosynthesis from Acinetobacter baumannii. Commun Biol, 6, 2023
8GTI	Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C205 by XFEL 分子名称: 8-(4-bromanyl-2,6-dimethoxy-phenyl)-~{N}-butyl-~{N}-(cyclopropylmethyl)-2,7-dimethyl-pyrazolo[1,5-a][1,3,5]triazin-4-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1, ... 著者 Cho, H.S, Kim, H. 登録日 2022-09-08 公開日 2023-09-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
2YYG	Crystal structure of the oxygenase component (HpaB) of 4-hydroxyphenylacetate 3-monooxygenase 分子名称: 4-hydroxyphenylacetate-3-hydroxylase, SULFATE ION 著者 Kim, S.-H, Hisano, T, Takeda, K, Iwasaki, W, Ebihara, A, Miki, K. 登録日 2007-04-30 公開日 2007-09-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal Structure of the Oxygenase Component (HpaB) of the 4-Hydroxyphenylacetate 3-Monooxygenase from Thermus thermophilus HB8 J.Biol.Chem., 282, 2007
8G95	Adenylation domain structure from NRPS-like Delta-Poly-L-Ornithine synthetase 分子名称: 1,2-ETHANEDIOL, CACODYLATE ION, Dimodular nonribosomal peptide synthase 著者 Patel, K.D, Gulick, A.M. 登録日 2023-02-21 公開日 2023-10-04 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and functional insights into delta-poly-L-ornithine polymer biosynthesis from Acinetobacter baumannii. Commun Biol, 6, 2023
8G98	Adenylation domain structure from NRPS-like Delta-Poly-L-Ornithine synthetase (L-Lysine bound) 分子名称: Dimodular nonribosomal peptide synthase, GLYCEROL, LYSINE 著者 Patel, K.D, Gulick, A.M. 登録日 2023-02-21 公開日 2023-10-04 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 Structural and functional insights into delta-poly-L-ornithine polymer biosynthesis from Acinetobacter baumannii. Commun Biol, 6, 2023
8GTM	Corticotropin-releasing hormone receptor 1(CRF1R) bound with BMK-C203 by XFEL 分子名称: 7-(4-bromanyl-2,6-dimethoxy-phenyl)-4,8-dimethyl-~{N},~{N}-bis[4,4,4-tris(fluoranyl)butyl]-1$l^{4},3,5,9-tetrazabicyclo[4.3.0]nona-1(6),2,4,8-tetraen-2-amine, Endolysin, Isoform CRF-R2 of Corticotropin-releasing factor receptor 1 著者 Cho, H.S, Kim, H. 登録日 2022-09-08 公開日 2023-09-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure-based drug discovery of a corticotropin-releasing hormone receptor 1 antagonist using an X-ray free-electron laser. Exp.Mol.Med., 55, 2023
8G5T	Crystal structure of apo TnmK2 分子名称: TnmK2 著者 Liu, Y.-C, Gui, C, Shen, B. 登録日 2023-02-14 公開日 2023-10-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.846 Å) 主引用文献 Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis. Nat.Chem.Biol., 20, 2024
8G5U	Crystal structure of TnmK2 complexed with TNM B 分子名称: TnmK2, methyl (2E)-3-[(1aS,11S,11aS,14Z,18R)-3,18-dihydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]but-2-enoate 著者 Liu, Y.-C, Gui, C, Shen, B. 登録日 2023-02-14 公開日 2023-10-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.804 Å) 主引用文献 Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis. Nat.Chem.Biol., 20, 2024
8G97	Adenylation domain structure from NRPS-like Delta-Poly-L-Ornithine synthetase (D-Ornithine bound) 分子名称: D-ORNITHINE, Dimodular nonribosomal peptide synthase, GLYCEROL, ... 著者 Patel, K.D, Gulick, A.M. 登録日 2023-02-21 公開日 2023-10-04 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structural and functional insights into delta-poly-L-ornithine polymer biosynthesis from Acinetobacter baumannii. Commun Biol, 6, 2023
8G5S	Crystal structure of apo TnmJ 分子名称: TnmJ 著者 Liu, Y.-C, Li, G, Gui, C, Shen, B. 登録日 2023-02-14 公開日 2023-10-18 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis. Nat.Chem.Biol., 20, 2024
8G6U	Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with 8ANC195 and 10-1074 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CRF-1_AE T/F100 HIV-1 gp41, ... 著者 Chen, Y, Zhou, F, Huang, R, Tolbert, W, Pazgier, M. 登録日 2023-02-16 公開日 2023-11-08 実験手法 ELECTRON MICROSCOPY (3.16 Å) 主引用文献 Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir. Nat Commun, 14, 2023
7JH0	Crystallographic structure of glyceraldehyde-3-phosphate dehydrogenase from Schistosoma mansoni 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Boreiko, S, Silva, M, Iulek, J. 登録日 2020-07-20 公開日 2021-02-17 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Structure determination and analyses of the GAPDH from the parasite Schistosoma mansoni, the first one from a platyhelminth. Biochimie, 184, 2021
3HPM	Oxidized dimeric PICK1 PDZ C46G mutant in complex with the carboxyl tail peptide of GluR2 分子名称: PRKCA-binding protein,9-mer peptide of THE GLUR2 SUBUNIT 著者 Yu, J, Shi, Y, Zhang, M. 登録日 2009-06-04 公開日 2010-06-09 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Redox-Regulated Lipid Membrane Binding of the PICK1 PDZ Domain. Biochemistry, 49, 2010
2YYI	Crystal structure of the oxygenase component (HpaB) of 4-hydroxyphenylacetate 3-monooxygenase complexed with FAD 分子名称: 4-hydroxyphenylacetate-3-hydroxylase, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION 著者 Kim, S.-H, Hisano, T, Takeda, K, Iwasaki, W, Ebihara, A, Miki, K. 登録日 2007-04-30 公開日 2007-09-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Crystal Structure of the Oxygenase Component (HpaB) of the 4-Hydroxyphenylacetate 3-Monooxygenase from Thermus thermophilus HB8 J.Biol.Chem., 282, 2007
7JJT	Ruminococcus bromii amylase Amy5 (RBR_07800) 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Alpha-amylase, ... 著者 Cerqueira, F, Koropatkin, N. 登録日 2020-07-27 公開日 2021-06-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 The structures of the GH13_36 amylases from Eubacterium rectale and Ruminococcus bromii reveal subsite architectures that favor maltose production Amylase, 4, 2020
8GLZ	Crystal structure of T252E-CYP199A4 in complex with 4-hydroxybenzoic acid. Crystal was initially co-crystallised with 4-methoxybenzoic acid and soaked with 4 mM hydrogen peroxide 分子名称: CHLORIDE ION, Cytochrome P450, P-HYDROXYBENZOIC ACID, ... 著者 Lee, J.H.Z, Bruning, J.B, Bell, S.G. 登録日 2023-03-23 公開日 2023-12-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 An In Crystallo Reaction with an Engineered Cytochrome P450 Peroxygenase. Chemistry, 30, 2024
8GM2	Crystal structure of T252E-CYP199A4 in complex with 4-methoxybenzoic acid soaked with 2 mM hydrogen peroxide 分子名称: 4-METHOXYBENZOIC ACID, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE 著者 Lee, J.H.Z, Bruning, J.B, Bell, S.G. 登録日 2023-03-24 公開日 2023-12-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 An In Crystallo Reaction with an Engineered Cytochrome P450 Peroxygenase. Chemistry, 30, 2024
8G6D	HSV-1 Nuclear Egress Complex (SUP; UL31-R229L) 分子名称: Nuclear egress protein 1, Virion egress protein UL34, ZINC ION 著者 Draganova, E.B, Gonzalez Del-Pino, G.L, Heldwein, E.E. 登録日 2023-02-15 公開日 2024-01-10 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.92 Å) 主引用文献 The universal suppressor mutation restores membrane budding defects in the HSV-1 nuclear egress complex by stabilizing the oligomeric lattice. Plos Pathog., 20, 2024
3VFG	Crystal structure of monoclonal antibody 3F8 Fab fragment that binds to GD2 ganglioside 分子名称: 3F8 Heavy Chain, 3F8 Light Chain 著者 Ahmed, M, Goldgur, Y, Cheung, N.-K. 登録日 2012-01-09 公開日 2013-02-06 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 In silico Driven Redesign of a Clinically Relevant Antibody for the Treatment of GD2 Positive Tumors. Plos One, 8, 2013
2YYJ	Crystal structure of the oxygenase component (HpaB) of 4-hydroxyphenylacetate 3-monooxygenase complexed with FAD and 4-hydroxyphenylacetate 分子名称: 4-HYDROXYPHENYLACETATE, 4-hydroxyphenylacetate-3-hydroxylase, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Kim, S.-H, Hisano, T, Takeda, K, Iwasaki, W, Ebihara, A, Miki, K. 登録日 2007-04-30 公開日 2007-09-04 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Crystal Structure of the Oxygenase Component (HpaB) of the 4-Hydroxyphenylacetate 3-Monooxygenase from Thermus thermophilus HB8 J.Biol.Chem., 282, 2007
8GEN	E. eligens beta-glucuronidase bound to UNC10201652-glucuronide 分子名称: 8-(4-beta-D-glucopyranuronosylpiperazin-1-yl)-5-(morpholin-4-yl)-1,2,3,4-tetrahydro[1,2,3]triazino[4',5':4,5]thieno[2,3 -c]isoquinoline, Beta-glucuronidase 著者 Simpson, J.B, Redinbo, M.R. 登録日 2023-03-07 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.94 Å) 主引用文献 Diverse Human Therapeutics Impact Hormone and Neurotransmitter Homeostasis by Inhibiting Gut Microbial Enzymes To Be Published
7JJ1	Crystal structure of the sterol 14alpha-demethylase-ferredoxin (CYP51-fx) heme domain and architectural comparison to the whole fusion protein 分子名称: CETYL-TRIMETHYL-AMMONIUM, Cytochrome P450 51, IMIDAZOLE, ... 著者 Zhao, B, Lamb, D.C. 登録日 2020-07-24 公開日 2021-07-28 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of the sterol 14alpha-demethylase-ferredoxin (CYP51-fx) heme domain and architectural comparison to the whole fusion protein To Be Published
8GEQ	E. eligens beta-glucuronidase bound to ceritinib-glucuronide 分子名称: 4-amino-5-chloro-2-{4-(1-beta-D-glucopyranuronosylpiperidin-4-yl)-5-methyl-2-[(propan-2-yl)oxy]anilino}pyrimidine, Beta-glucuronidase 著者 Simpson, J.B, Kowalewski, M.K, Redinbo, M.R. 登録日 2023-03-07 公開日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Diverse Human Therapeutics Impact Hormone and Neurotransmitter Homeostasis by Inhibiting Gut Microbial Enzymes To Be Published

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