8G5U
Crystal structure of TnmK2 complexed with TNM B
Summary for 8G5U
Entry DOI | 10.2210/pdb8g5u/pdb |
Descriptor | TnmK2, methyl (2E)-3-[(1aS,11S,11aS,14Z,18R)-3,18-dihydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]but-2-enoate (3 entities in total) |
Functional Keywords | biosynthesis, natural product, tiancimycin, enediyne, biosynthetic protein |
Biological source | Streptomyces sp. CB03234 |
Total number of polymer chains | 4 |
Total formula weight | 216287.29 |
Authors | Liu, Y.-C.,Gui, C.,Shen, B. (deposition date: 2023-02-14, release date: 2023-10-18, Last modification date: 2024-02-14) |
Primary citation | Gui, C.,Kalkreuter, E.,Liu, Y.C.,Li, G.,Steele, A.D.,Yang, D.,Chang, C.,Shen, B. Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis. Nat.Chem.Biol., 20:243-250, 2024 Cited by PubMed: 37945897DOI: 10.1038/s41589-023-01476-2 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.804 Å) |
Structure validation
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