PDB: 47065 件ウェブページステータス検索Chemie searchBIRD

---

5VZJ	STRUCTURE OF A TWELVE COMPONENT MPP6-NUCLEAR RNA EXOSOME COMPLEX BOUND TO RNA 分子名称: Exosome complex component CSL4, Exosome complex component MTR3, Exosome complex component RRP4, ... 著者 Lima, C.D, Wasmuth, E.V. 登録日 2017-05-28 公開日 2017-08-02 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase. Elife, 6, 2017
5VSW	X-ray crystal structure of Escherichia coli RNA polymerase and DksA/ppGpp complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2017-05-12 公開日 2017-06-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (4.295 Å) 主引用文献 Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA. Mol. Cell, 69, 2018
4ZF8	Cytochrome P450 pentamutant from BM3 with bound Metyrapone 分子名称: Bifunctional P-450/NADPH-P450 reductase, METYRAPONE, NICKEL (II) ION, ... 著者 Rogers, W.E, Othman, T, Heidary, D.K, Huxford, T. 登録日 2015-04-21 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.766 Å) 主引用文献 Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry, 55, 2016
4YYY	X-ray structure of the thymidine phosphorylase from Salmonella typhimurium in complex with uridine 分子名称: CITRIC ACID, TRIETHYLENE GLYCOL, Thymidine phosphorylase, ... 著者 Balaev, V.V, Lashkov, A.A, Gabdulkhakov, A.G, Betzel, C, Mikhailov, A.M. 登録日 2015-03-24 公開日 2016-03-09 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Structural investigation of the thymidine phosphorylase from Salmonella typhimurium in the unliganded state and its complexes with thymidine and uridine. Acta Crystallogr.,Sect.F, 72, 2016
5T9V	Structure of rabbit RyR1 (Caffeine/ATP/Ca2+ dataset, class 1) 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ... 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-09 公開日 2016-10-12 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
5TAX	Structure of rabbit RyR1 (ryanodine dataset, class 1) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... 著者 Clarke, O.B, des Georges, A, Zalk, R, Marks, A.R, Hendrickson, W.A, Frank, J. 登録日 2016-09-10 公開日 2016-10-12 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Structural Basis for Gating and Activation of RyR1. Cell, 167, 2016
4Z8Y	Crystal structure of Rab GTPase Sec4p mutant - S29V 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein SEC4, ... 著者 Rinadi, F.C, Collins, R.N. 登録日 2015-04-09 公開日 2015-10-14 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 New insights into the molecular mechanism of the Rab GTPase Sec4p activation. Bmc Struct.Biol., 15, 2015
5TBK	Crystal structure of human importin a3 bound to RCC1 分子名称: Importin subunit alpha-3, Regulator of chromosome condensation 著者 Sankhala, R.S, Lokareddy, R.K, Pumroy, R.A, Cingolani, G. 登録日 2016-09-12 公開日 2017-09-13 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Three-dimensional context rather than NLS amino acid sequence determines importin alpha subtype specificity for RCC1. Nat Commun, 8, 2017
5TMC	Re-refinement of Thermus thermopiles DNA-directed RNA polymerase structure 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Wang, J. 登録日 2016-10-12 公開日 2016-11-23 最終更新日 2019-02-20 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 On the validation of crystallographic symmetry and the quality of structures. Protein Sci., 24, 2015
5TJG	Thermus aquaticus delta1.1-sigmaA holoenzyme/downstream-fork promoter complex with an open clamp 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*A)-3'), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Darst, S.A, Bae, B. 登録日 2016-10-04 公開日 2017-06-21 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 RNA polymerase motions during promoter melting. Science, 356, 2017
5W1M	MACV GP1 CR1-07 Fab complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR1-07 Fab heavy chain, ... 著者 Raymond, D.D, Clark, L.E, Abraham, J. 登録日 2017-06-03 公開日 2018-05-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.91 Å) 主引用文献 Vaccine-elicited receptor-binding site antibodies neutralize two New World hemorrhagic fever arenaviruses. Nat Commun, 9, 2018
4Z84	PKAB3 in complex with pyrrolidine inhibitor 34a 分子名称: 7-[(3S,4R)-4-(3-chlorophenyl)carbonylpyrrolidin-3-yl]-3H-quinazolin-4-one, METHANOL, cAMP-dependent protein kinase catalytic subunit alpha, ... 著者 Lund, B.A, Alam, K.A, Engh, R.A. 登録日 2015-04-08 公開日 2015-12-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.554 Å) 主引用文献 Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of PKA and a PKB Mimic. Chemistry, 22, 2016
5VHM	Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle 分子名称: 26S proteasome non-ATPase regulatory subunit 10, 26S proteasome non-ATPase regulatory subunit 2, 26S proteasome regulatory subunit 10B, ... 著者 Lu, Y, Wu, J, Dong, Y, Chen, S, Sun, S, Ma, Y.B, Ouyang, Q, Finley, D, Kirschner, M.W, Mao, Y. 登録日 2017-04-13 公開日 2017-08-23 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (8.3 Å) 主引用文献 Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle. Mol. Cell, 67, 2017
5VI8	Structure of a mycobacterium smegmatis transcription initiation complex with an upstream-fork promoter fragment 分子名称: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... 著者 Hubin, E.A, Campbell, E.A, Darst, S.A. 登録日 2017-04-14 公開日 2017-04-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures. Nat Commun, 8, 2017
4ZCU	Structure of calcium-bound regulatory domain of the human ATP-Mg/Pi carrier in the P2 form 分子名称: CALCIUM ION, Calcium-binding mitochondrial carrier protein SCaMC-1, GLYCEROL, ... 著者 Harborne, S.P.D, Ruprecht, J.J, Kunji, E.R.S. 登録日 2015-04-16 公開日 2015-07-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Calcium-induced conformational changes in the regulatory domain of the human mitochondrial ATP-Mg/Pi carrier. Biochim.Biophys.Acta, 1847, 2015
5VK6	Open conformation of KcsA non-inactivating E71A mutant 分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ... 著者 Cuello, L.G, Perozo, E. 登録日 2017-04-21 公開日 2017-12-06 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 The gating cycle of a K+ channel at atomic resolution. Elife, 6, 2017
4ZFB	Cytochrome P450 pentamutant from BM3 bound to Palmitic Acid 分子名称: 1,2-ETHANEDIOL, Bifunctional P-450/NADPH-P450 reductase, NICKEL (II) ION, ... 著者 Rogers, W.E, Othman, T, Heidary, D.K, Huxford, T. 登録日 2015-04-21 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.84 Å) 主引用文献 Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry, 55, 2016
5VKE	Open conformation of KcsA deep-inactivated 分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Heavy Chain, Antibody Light Chain, ... 著者 Cuello, L.G, Perozo, E, Cortes, D.M. 登録日 2017-04-21 公開日 2017-12-06 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 The gating cycle of a K+ channel at atomic resolution. Elife, 6, 2017
5VKQ	Structure of a mechanotransduction ion channel Drosophila NOMPC in nanodisc 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSHOCHOLINE, No mechanoreceptor potential C isoform L 著者 Jin, P, Bulkley, D, Guo, Y, Zhang, W, Guo, Z, Huynh, W, Wu, S, Meltzer, S, Chen, T, Jan, L.Y, Jan, Y.-N, Cheng, Y. 登録日 2017-04-22 公開日 2017-06-28 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.55 Å) 主引用文献 Electron cryo-microscopy structure of the mechanotransduction channel NOMPC. Nature, 547, 2017
4ZH3	Crystal structure of Escherichia coli RNA polymerase in complex with CBRH16-Br 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Feng, Y, Ebright, R.H. 登録日 2015-04-24 公開日 2015-08-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.082 Å) 主引用文献 Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. Structure, 23, 2015
4Z2W	Factor Inhibiting HIF in Complex with Fe, and Alpha-Ketoglutarate 分子名称: 2-OXOGLUTARIC ACID, DI(HYDROXYETHYL)ETHER, FE (III) ION, ... 著者 Taabazuing, C.Y, Garman, S.C, Knapp, M.J. 登録日 2015-03-30 公開日 2016-01-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Substrate Promotes Productive Gas Binding in the alpha-Ketoglutarate-Dependent Oxygenase FIH. Biochemistry, 55, 2016
4ZFA	Cytochrome P450 wild type from BM3 with bound PEG 分子名称: 1,2-ETHANEDIOL, Bifunctional P-450/NADPH-P450 reductase, NICKEL (II) ION, ... 著者 Rogers, W.E, Othman, T, Heidary, D.K, Huxford, T. 登録日 2015-04-21 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.765 Å) 主引用文献 Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry, 55, 2016
5VCB	Crystal structure of holo-(acyl-carrier-protein) synthase:holo(acyl-carrier-protein) complex from Escherichia Coli. 分子名称: 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, Holo-[acyl-carrier-protein] synthase 著者 Marcella, A.M, Barb, A.W. 登録日 2017-03-31 公開日 2017-11-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Structure, High Affinity, and Negative Cooperativity of the Escherichia coli Holo-(Acyl Carrier Protein):Holo-(Acyl Carrier Protein) Synthase Complex. J. Mol. Biol., 429, 2017
4ZGX	Structure of aldosterone synthase (CYP11B2) in complex with (+)-(R)-N-(4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl)propionamide 分子名称: Cytochrome P450 11B2, mitochondrial, N-[(8R)-4-(4-chloro-3-fluorophenyl)-5,6,7,8-tetrahydroisoquinolin-8-yl]propanamide, ... 著者 Kuglstatter, A, Joseph, C. 登録日 2015-04-24 公開日 2015-10-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Discovery of 4-Aryl-5,6,7,8-tetrahydroisoquinolines as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors: In Vivo Evaluation in Rodents and Cynomolgus Monkeys. J.Med.Chem., 58, 2015
4Z83	PKAB3 in complex with pyrrolidine inhibitor 47a 分子名称: 7-{(3S,4R)-4-[(5-bromothiophen-2-yl)carbonyl]pyrrolidin-3-yl}quinazolin-4(3H)-one, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha 著者 Lund, B.A, Alam, K.A, Engh, R.A. 登録日 2015-04-08 公開日 2015-12-02 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Addressing the Glycine-Rich Loop of Protein Kinases by a Multi-Facetted Interaction Network: Inhibition of PKA and a PKB Mimic. Chemistry, 22, 2016

<595596597598599600601602603604605606607608609610>