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1LAI
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Solution Structure of the B-DNA Duplex CGCGGTGTCCGCG.
分子名称: 5'-D(*CP*GP*CP*GP*GP*AP*CP*AP*CP*CP*GP*CP*G)-3', 5'-D(*CP*GP*CP*GP*GP*TP*GP*TP*CP*CP*GP*CP*G)-3'
著者Weisenseel, J.P, Reddy, G.R, Marnett, L.J, Stone, M.P.
登録日2002-03-28
公開日2002-04-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of an oligodeoxynucleotide containing a 1,N(2)-propanodeoxyguanosine adduct positioned in a palindrome derived from the Salmonella typhimurium hisD3052 gene: Hoogsteen pairing at pH 5.2.
Chem.Res.Toxicol., 15, 2002
3W97
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BU of 3w97 by Molmil
Crystal Structure of Human Nucleosome Core Particle lacking H2B N-terminal region
分子名称: 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H.
登録日2013-04-01
公開日2013-08-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
1LAS
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BU of 1las by Molmil
Solution Structure of the B-DNA Duplex CGCGGTXTCCGCG (X=PdG) Containing the 1,N2-propanodeoxyguanosine Adduct with the Deoxyribose at C20 Opposite PdG in the C3' Endo Conformation.
分子名称: 5'-D(*CP*GP*CP*GP*GP*AP*(DNR)P*AP*CP*CP*GP*CP*G)-3', 5'-D(*CP*GP*CP*GP*GP*TP*(P)P*TP*CP*CP*GP*CP*G)-3'
著者Weisenseel, J.P, Reddy, G.R, Marnett, L.J, Stone, M.P.
登録日2002-03-29
公開日2002-04-17
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of an oligodeoxynucleotide containing a 1,N(2)-propanodeoxyguanosine adduct positioned in a palindrome derived from the Salmonella typhimurium hisD3052 gene: Hoogsteen pairing at pH 5.2.
Chem.Res.Toxicol., 15, 2002
3OWV
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Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae
分子名称: CHLORIDE ION, DNA-entry nuclease, MAGNESIUM ION
著者Moon, A.F, Midon, M, Meiss, G, Pingoud, A.M, London, R.E, Pedersen, L.C.
登録日2010-09-20
公開日2010-12-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural insights into catalytic and substrate binding mechanisms of the strategic EndA nuclease from Streptococcus pneumoniae.
Nucleic Acids Res., 39, 2011
3HQG
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Crystal structure of restriction endonuclease EcoRII catalytic C-terminal domain in complex with cognate DNA
分子名称: 5'-D(*TP*AP*GP*CP*CP*TP*GP*GP*TP*CP*GP*A)-3', 5'-D(*TP*CP*GP*AP*CP*CP*AP*GP*GP*CP*TP*A)-3', GLYCEROL, ...
著者Golovenko, D, Manakova, E, Grazulis, S, Tamulaitiene, G, Siksnys, V.
登録日2009-06-06
公開日2009-09-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural mechanisms for the 5'-CCWGG sequence recognition by the N- and C-terminal domains of EcoRII.
Nucleic Acids Res., 37, 2009
5AKN
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BU of 5akn by Molmil
THE CRYSTAL STRUCTURE OF I-DMOI Q42AK120M IN COMPLEX WITH ITS TARGET DNA NICKED IN THE non-CODING STRAND B AND IN THE PRESENCE OF 2MM MN
分子名称: 5'-D(*CP*CP*GP*GP*CP*AP*AP*GP*GP*CP)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP *CP*GP*CP*GP*CP*CP*GP*GP*AP*AP*CP*TP*TP*AP*C)-3', 5'-D(*GP*CP*CP*TP*TP*GP*CP*CP*GP*GP*GP*TP*AP*AP)-3', ...
著者Molina, R, Marcaida, M.J, Redondo, P, Marenchino, M, D'Abramo, M, Montoya, G, Prieto, J.
登録日2015-03-04
公開日2015-06-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Engineering a Nickase on the Homing Endonuclease I-Dmoi Scaffold.
J.Biol.Chem., 290, 2015
482D
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RELEASE OF THE CYANO MOIETY IN THE CRYSTAL STRUCTURE OF N-CYANOMETHYL-N-(2-METHOXYETHYL)-DAUNOMYCIN COMPLEXED WITH D(CGATCG)
分子名称: 5'-D(*CP*GP*AP*TP*CP*G)-3', N-HYDROXYMETHYL-N-(2-METHOXYETHYL)-DAUNOMYCIN
著者Saminadin, P, Dautant, A, Mondon, M, Langlois D'Estaintot, B, Courseille, C, Precigoux, G.
登録日1999-07-27
公開日1999-09-15
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.54 Å)
主引用文献Release of the cyano moiety in the crystal structure of N-cyanomethyl-N-(2-methoxyethyl)-daunomycin complexed with d(CGATCG).
Eur.J.Biochem., 267, 2000
1ENN
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BU of 1enn by Molmil
SOLVENT ORGANIZATION IN AN OLIGONUCLEOTIDE CRYSTAL: THE STRUCTURE OF D(GCGAATTCG)2 AT ATOMIC RESOLUTION
分子名称: CHLORIDE ION, DNA (5'-D(*GP*CP*GP*AP*AP*TP*TP*CP*G)-3'), MAGNESIUM ION, ...
著者Soler-Lopez, M, Malinina, L, Subirana, J.A.
登録日2000-03-21
公開日2000-05-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (0.89 Å)
主引用文献Solvent organization in an oligonucleotide crystal. The structure of d(GCGAATTCG)2 at atomic resolution.
J.Biol.Chem., 275, 2000
5EJL
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MrkH, A novel c-di-GMP dependence transcription regulatory factor.
分子名称: 1,2-ETHANEDIOL, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Klebsiella pneumoniae genome assembly NOVST, ...
著者Wang, F, Zhu, D, Gu, L.
登録日2015-11-02
公開日2016-10-19
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The PilZ domain of MrkH represents a novel DNA binding motif
Protein Cell, 7, 2016
2JT7
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NMR solution structure of the 4:1 distamycin A/[d(TGGGGT)]4 complex
分子名称: DISTAMYCIN A, DNA (5'-D(*DTP*DGP*DGP*DGP*DGP*DT)-3')
著者Martino, L, Virno, A.
登録日2007-07-20
公開日2008-01-29
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structural and thermodynamic studies of the interaction of distamycin A with the parallel quadruplex structure [d(TGGGGT)]4
J.Am.Chem.Soc., 129, 2007
8CG3
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Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 1)
分子名称: TAR DNA-binding protein 43
著者Arseni, D, Ryskeldi-Falcon, B.
登録日2023-02-03
公開日2023-08-02
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Nature, 620, 2023
8CGG
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Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 2)
分子名称: TAR DNA-binding protein 43
著者Arseni, D, Ryskeldi-Falcon, B.
登録日2023-02-04
公開日2023-08-02
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Nature, 620, 2023
8CGH
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BU of 8cgh by Molmil
Structure of TDP-43 amyloid filament from type A FTLD-TDP (variant 3)
分子名称: TAR DNA-binding protein 43
著者Arseni, D, Ryskeldi-Falcon, B.
登録日2023-02-04
公開日2023-08-02
最終更新日2023-08-30
実験手法ELECTRON MICROSCOPY (2.68 Å)
主引用文献TDP-43 forms amyloid filaments with a distinct fold in type A FTLD-TDP.
Nature, 620, 2023
8FDR
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Structure of a dodecamer complex: 5'-CGCGAAAAGCCG-3-DB1476
分子名称: 4,4'-(1H-benzimidazole-2,6-diyl)di(benzene-1-carboximidamide), DNA (5'-D(*CP*GP*CP*GP*AP*AP*AP*AP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*TP*TP*TP*TP*CP*GP*CP*G)-3'), ...
著者Ogbonna, E, Wilson, W.D.
登録日2022-12-04
公開日2023-02-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献X-ray Structure Characterization of the Selective Recognition of AT Base Pair Sequences.
Acs Bio Med Chem Au, 3, 2023
8THO
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BU of 8tho by Molmil
Solution structure of the zinc finger repeat domain of BCL11A (ZnF456)
分子名称: B-cell lymphoma/leukemia 11A, ZINC ION
著者Viennet, T, Yin, M, Orkin, S.H, Arthanari, H.
登録日2023-07-17
公開日2024-07-24
実験手法SOLUTION NMR
主引用文献Structural and dynamic investigation of DNA-binding by BCL11A reveals a specific role for ZnF6
To Be Published
1Y86
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Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(fluoro)ethyl] Thymidine (T*)
分子名称: 5'-D(*GP*CP*GP*TP*AP*(125)P*AP*CP*GP*C)-3'
著者Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
登録日2004-12-10
公開日2005-06-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1RR8
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BU of 1rr8 by Molmil
Structural Mechanisms of Camptothecin Resistance by Mutations in Human Topoisomerase I
分子名称: (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE, 2-(1-DIMETHYLAMINOMETHYL-2-HYDROXY-8-HYDROXYMETHYL-9-OXO-9,11-DIHYDRO-INDOLIZINO[1,2-B]QUINOLIN-7-YL)-2-HYDROXY-BUTYRIC ACID, 5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*T*GP*GP*AP*AP*AP*AP*AP*TP*TP*TP*TP*T)-3', ...
著者Chrencik, J.E, Staker, B.L, Burgin, A.B, Stewart, L, Redinbo, M.R.
登録日2003-12-08
公開日2004-07-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Mechanisms of camptothecin resistance by human topoisomerase I mutations
J.Mol.Biol., 339, 2004
1Y84
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Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-(imidazolyl)ethyl] Thymidine (T*)
分子名称: 5'-D(*GP*CP*GP*TP*AP*(EIT)P*AP*CP*GP*C)-3', MAGNESIUM ION, SPERMINE
著者Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
登録日2004-12-10
公開日2005-06-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
1KBU
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CRE RECOMBINASE BOUND TO A LOXP HOLLIDAY JUNCTION
分子名称: CRE RECOMBINASE, LOXP
著者Martin, S.S, Pulido, E, Chu, V.C, Lechner, T, Baldwin, E.P.
登録日2001-11-06
公開日2002-06-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Order of Strand Exchanges in Cre-LoxP Recombination and its Basis Suggested by the Crystal Structure of a Cre-LoxP Holliday Junction Complex
J.Mol.Biol., 319, 2002
4TU9
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STRUCTURE OF U2AF65 VARIANT WITH BRU5G6 DNA
分子名称: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*DG*U)-3'), GLYCEROL, ...
著者Jenkins, J.L, McLaughlin, K.J, Agrawal, A.A, Kielkopf, C.L.
登録日2014-06-24
公開日2014-11-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.992 Å)
主引用文献Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA.
Proc.Natl.Acad.Sci.USA, 111, 2014
8K26
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Structure of Cas1-Cas2 complex
分子名称: Cas1, HD Cas3-type domain-containing protein
著者Zhang, L.X, Feng, Y.
登録日2023-07-12
公開日2024-07-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of csy complex with short DNA
To Be Published
1Y7F
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BU of 1y7f by Molmil
Crystal structure of the A-DNA GCGTAT*CGC with a 2'-O-[2-[hydroxy(methyleneamino)oxy]ethyl] Thymidine (T*)
分子名称: 5'-D(*GP*CP*GP*TP*AP*(2NT)P*AP*CP*GP*C)-3'), BARIUM ION
著者Egli, M, Minasov, G, Tereshko, V, Pallan, P.S, Teplova, M, Inamati, G.B, Lesnik, E.A, Owens, S.R, Ross, B.S, Prakash, T.P, Manoharan, M.
登録日2004-12-08
公開日2005-06-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Probing the Influence of Stereoelectronic Effects on the Biophysical Properties of Oligonucleotides: Comprehensive Analysis of the RNA Affinity, Nuclease Resistance, and Crystal Structure of Ten 2'-O-Ribonucleic Acid Modifications.
Biochemistry, 44, 2005
4TU8
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STRUCTURE OF U2AF65 VARIANT WITH BRU5A6 DNA
分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*DA*U)-3'), ...
著者MCLAUGHLIN, K.J, JENKINS, J.L, Agrawal, A.A, KIELKOPF, C.L.
登録日2014-06-24
公開日2014-11-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.918 Å)
主引用文献Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA.
Proc.Natl.Acad.Sci.USA, 111, 2014
3QMD
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Structural Basis of Selective Binding of Nonmethylated CpG Islands by the CXXC Domain of CFP1
分子名称: CpG-binding protein, DNA (5'-D(*GP*CP*CP*AP*AP*CP*GP*AP*TP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*AP*TP*CP*GP*TP*TP*GP*GP*C)-3'), ...
著者Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2011-02-04
公開日2011-02-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for selective binding of non-methylated CpG islands by the CFP1 CXXC domain.
Nat Commun, 2, 2011
4TU7
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Structure of U2AF65 D231V variant with BrU5 DNA
分子名称: 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*UP*UP*UP*UP*(BRU)P*UP*U)-3'), GLYCEROL, ...
著者Agrawal, A.A, Jenkins, J.L, Kielkopf, C.L.
登録日2014-06-24
公開日2014-11-26
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.087 Å)
主引用文献Structure-guided U2AF65 variant improves recognition and splicing of a defective pre-mRNA.
Proc.Natl.Acad.Sci.USA, 111, 2014

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