Solution Structure of the B-DNA Duplex CGCGGTXTCCGCG (X=PdG) Containing the 1,N2-propanodeoxyguanosine Adduct with the Deoxyribose at C20 Opposite PdG in the C3' Endo Conformation.

Summary for 1LAS

Related1LAB 1LAE 1LAI 1LAQ
Descriptor5'-D(*CP*GP*CP*GP*GP*TP*(P)P*TP*CP*CP*GP*CP*G)-3', 5'-D(*CP*GP*CP*GP*GP*AP*(DNR)P*AP*CP*CP*GP*CP*G)-3' (2 entities in total)
Functional Keywordsdna, b-type, propanodeoxyguanosine
Total number of polymer chains2
Total molecular weight7988.22
Weisenseel, J.P.,Reddy, G.R.,Marnett, L.J.,Stone, M.P. (deposition date: 2002-03-29, release date: 2002-04-17, Last modification date: 2011-07-13)
Primary citation
Weisenseel, J.P.,Reddy, G.R.,Marnett, L.J.,Stone, M.P.
Structure of an oligodeoxynucleotide containing a 1,N(2)-propanodeoxyguanosine adduct positioned in a palindrome derived from the Salmonella typhimurium hisD3052 gene: Hoogsteen pairing at pH 5.2.
Chem.Res.Toxicol., 15:127-139, 2002
PubMed: 11849038 (PDB entries with the same primary citation)
DOI: 10.1021/tx0101090
MImport into Mendeley
Experimental method

Structure validation

Clashscore12MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures