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5D7A
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Crystal structure of the kinase domain of TRAF2 and NCK-interacting protein kinase with NCB-0846
分子名称: SULFATE ION, TRAF2 and NCK-interacting protein kinase, cis-4-{[2-(1H-benzimidazol-5-ylamino)quinazolin-8-yl]oxy}cyclohexanol
著者Ohbayashi, N, Kukimoto-Niino, M, Yamada, T, Shirouzu, M.
登録日2015-08-13
公開日2016-08-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献TNIK inhibition abrogates colorectal cancer stemness
Nat Commun, 7, 2016
5CWZ
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BU of 5cwz by Molmil
Crystal structure of the kinase domain of human TRAF2 and NCK-interacting protein kinase
分子名称: TRAF2 and NCK-interacting protein kinase
著者Ohbayashi, N, Kukimoto-Niino, M, Yamada, T, Shirouzu, M.
登録日2015-07-28
公開日2016-07-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献TNIK inhibition abrogates colorectal cancer stemness
Nat Commun, 7, 2016
5AX9
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BU of 5ax9 by Molmil
Crystal structure of the kinase domain of human TRAF2 and NCK-interacting protein kinase in complex with compund 9
分子名称: 4-methoxy-3-[2-[(3-methoxy-4-morpholin-4-yl-phenyl)amino]pyridin-4-yl]benzenecarbonitrile, SULFATE ION, TRAF2 and NCK-interacting protein kinase
著者Ohbayashi, N, Kukimoto-Niino, M, Yamada, T, Shirouzu, M.
登録日2015-07-21
公開日2016-07-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献TNIK inhibition abrogates colorectal cancer stemness
Nat Commun, 7, 2016
6LKC
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BU of 6lkc by Molmil
Crystal structure of PfaD from Shewanella piezotolerans in complex with FMN
分子名称: CALCIUM ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
著者Zhang, M.L, Li, Q, Meng, S.S, Guo, L.J, He, L, Huang, J.Z, Li, L, Zhang, H.D.
登録日2019-12-19
公開日2020-12-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.998 Å)
主引用文献Structural Insights into the Trans -Acting Enoyl Reductase in the Biosynthesis of Long-Chain Polyunsaturated Fatty Acids in Shewanella piezotolerans .
J.Agric.Food Chem., 69, 2021
5U9K
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BU of 5u9k by Molmil
Crystal structure of V71F mutant of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1)
分子名称: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1)
著者Yadav, R.P, Gakhar, L, Liping, Y, Artemyev, N.O.
登録日2016-12-16
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U9A
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BU of 5u9a by Molmil
Crystal structure of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1)
分子名称: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1)
著者Yadav, R.P, Gakhar, L, Liping, Y, Artemyev, N.O.
登録日2016-12-15
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U9J
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BU of 5u9j by Molmil
Crystal structure of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) complexed with geranyl geranyl pyrophoshate
分子名称: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), GERAN-8-YL GERAN, ISOPROPYL ALCOHOL, ...
著者Yadav, R.P, Gakhar, L, Liping, Y, Artemyev, N.O.
登録日2016-12-16
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5U9I
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BU of 5u9i by Molmil
Crystal structure of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) complexed with S-farnesyl-L-cysteine methyl ester
分子名称: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), FARNESYL
著者Yadav, R.P, Gakhar, L, Liping, Y, Artemyev, N.O.
登録日2016-12-16
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V35
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BU of 5v35 by Molmil
Crystal structure of V71F mutant of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) complexed with S-farnesyl-L-cysteine methyl ester
分子名称: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), FARNESYL
著者Yadav, R.P, Gakhar, L, Liping, Y, Artemyev, N.O.
登録日2017-03-06
公開日2017-07-26
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4N6J
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BU of 4n6j by Molmil
Crystal structure of human Striatin-3 coiled coil domain
分子名称: Striatin-3
著者Chen, C, Shi, Z, Zhou, Z.
登録日2013-10-13
公開日2014-02-26
最終更新日2019-12-25
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Striatins contain a noncanonical coiled coil that binds protein phosphatase 2A A subunit to form a 2:2 heterotetrameric core of striatin-interacting phosphatase and kinase (STRIPAK) complex.
J.Biol.Chem., 289, 2014
4Z38
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BU of 4z38 by Molmil
Crystal structure of enoyl reductase domain of MlnA from the macrolactin biosynthesis cluster from Bacillus amyloliquefaciens
分子名称: FLAVIN MONONUCLEOTIDE, MlnA
著者Jakob, R.P, Martin, S.F, Herbst, D.A, Maier, T.
登録日2015-03-31
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The structural organization of trans-AT polyketide synthases: ketoacyl synthase and trans-acting enoyl reductase
To Be Published
4UT5
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BU of 4ut5 by Molmil
Crystal structure of the LecB lectin from Pseudomonas aeruginosa strain PA7 in complex with lewis a tetrasaccharide
分子名称: CALCIUM ION, LECB LECTIN, beta-D-galactopyranose, ...
著者Boukerb, A.M, Decor, A, Tabaroni, R, Varrot, A, Debentzmann, S, Vidal, S, Imberty, A, Cournoyer, B.
登録日2014-07-18
公開日2015-07-22
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Genomic Rearrangements and Functional Diversification of Leca and Lecb Lectin-Coding Regions Impacting the Efficacy of Glycomimetics Directed Against Pseudomonas Aeruginosa.
Front.Microbiol., 7, 2016
5AWR
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BU of 5awr by Molmil
Crystal structure of the SGIP1 mu homology domain in the P4212 space group
分子名称: SH3-containing GRB2-like protein 3-interacting protein 1, ZINC ION
著者Shimada, A, Yamaguchi, A, Kohda, D.
登録日2015-07-08
公開日2016-07-06
最終更新日2020-02-26
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 mu homology domain.
Sci Rep, 6, 2016
6E31
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BU of 6e31 by Molmil
Crystal structure of RIAM in an autoinhibited configuration.
分子名称: Rap1-interacting adapter molecule
著者Chang, Y.C, Su, W, Zhang, H, Huang, Q, Philips, M.R, Wu, J.
登録日2018-07-12
公開日2019-02-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for autoinhibition of RIAM regulated by FAK in integrin activation.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6U46
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BU of 6u46 by Molmil
Solution Structure of a Heat-Resistant Long-Acting Insulin Analog
分子名称: Insulin
著者Yang, Y, Weiss, M.A.
登録日2019-08-23
公開日2020-08-26
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution Structure of a Heat-Resistant Long-Acting Insulin Analog
To Be Published
6U79
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BU of 6u79 by Molmil
Solution NMR structure of 5' UTR stem loop B from West Nile Virus
分子名称: 5' UTR region stem loop
著者Sharma, S, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2019-09-01
公開日2020-08-26
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of Dengue West Nile viruses stem-loop B: A key cis-acting element for flavivirus replication.
Biochem.Biophys.Res.Commun., 531, 2020
5TX5
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BU of 5tx5 by Molmil
Rip1 Kinase ( flag 1-294, C34A, C127A, C233A, C240A) with GSK772
分子名称: 3-benzyl-N-[(3S)-5-methyl-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-5-carboxamide, Receptor-interacting serine/threonine-protein kinase 1
著者Campobasso, N, Ward, P, Thrope, J.
登録日2016-11-15
公開日2017-07-05
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases.
J. Med. Chem., 60, 2017
5CE7
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BU of 5ce7 by Molmil
Structure of a non-canonical CID of Ctk3
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CTD kinase subunit gamma
著者Muehlbacher, W, Mayer, A, Sun, M, Remmert, M, Cheung, A.C, Niesser, J, Soeding, J, Cramer, P.
登録日2015-07-06
公開日2015-08-05
最終更新日2015-09-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Ctk3, a subunit of the RNA polymerase II CTD kinase complex, reveals a noncanonical CTD-interacting domain fold.
Proteins, 83, 2015
5D94
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BU of 5d94 by Molmil
Crystal structure of LC3-LIR peptide complex
分子名称: Microtubule-associated proteins 1A/1B light chain 3B, Peptide from FYVE and coiled-coil domain-containing protein 1
著者Takagi, K, Mizushima, T, Johansen, T.
登録日2015-08-18
公開日2015-10-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献FYCO1 Contains a C-terminally Extended, LC3A/B-preferring LC3-interacting Region (LIR) Motif Required for Efficient Maturation of Autophagosomes during Basal Autophagy
J.Biol.Chem., 290, 2015
6W3M
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BU of 6w3m by Molmil
Solution NMR Structure of 5'UTR Stem Loop B in DENV4 Flavivirus.
分子名称: RNA (41-MER)
著者Sharma, S, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2020-03-09
公開日2020-09-23
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR structure of Dengue West Nile viruses stem-loop B: A key cis-acting element for flavivirus replication.
Biochem.Biophys.Res.Commun., 531, 2020
5AWS
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BU of 5aws by Molmil
Crystal structure of the SGIP1 mu homology domain in the P1 space group
分子名称: SH3-containing GRB2-like protein 3-interacting protein 1, ZINC ION
著者Shimada, A, Yamaguchi, A, Kohda, D.
登録日2015-07-08
公開日2016-07-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 mu homology domain.
Sci Rep, 6, 2016
5AWT
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BU of 5awt by Molmil
Crystal structure of the SGIP1 mu homology domain in complex with an Eps15 fragment containing two DPF motifs (YDPFGGDPFKG)
分子名称: Epidermal growth factor receptor substrate 15, SH3-containing GRB2-like protein 3-interacting protein 1, ZINC ION
著者Shimada, A, Yamaguchi, A, Kohda, D.
登録日2015-07-08
公開日2016-07-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 mu homology domain.
Sci Rep, 6, 2016
5DF6
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BU of 5df6 by Molmil
Crystal structure of PTPN11 tandem SH2 domains in complex with a TXNIP peptide
分子名称: Tyrosine-protein phosphatase non-receptor type 11, UNKNOWN ATOM OR ION, txnip
著者Dong, A, Li, W, Tempel, W, Liu, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2015-08-26
公開日2015-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structural basis for the regulatory role of the PPxY motifs in the thioredoxin-interacting protein TXNIP.
Biochem.J., 473, 2016
5AWU
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BU of 5awu by Molmil
Crystal structure of the SGIP1 mu homology domain in complex with an Eps15 fragment containing two DPF motifs (YDPFKGSDPFA)
分子名称: Epidermal growth factor receptor substrate 15, SH3-containing GRB2-like protein 3-interacting protein 1, ZINC ION
著者Shimada, A, Yamaguchi, A, Kohda, D.
登録日2015-07-08
公開日2016-07-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for the recognition of two consecutive mutually interacting DPF motifs by the SGIP1 mu homology domain.
Sci Rep, 6, 2016
6DSI
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BU of 6dsi by Molmil
Anti recombinant prolactin receptor scFv
分子名称: Anti-TN-C scFv
著者Langley, D.B, Rouet, R, Christ, D.
登録日2018-06-14
公開日2019-06-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Anti recombinant prolactin receptor scFv
To Be Published

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件を2024-07-31に公開中

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