5CWZ
Crystal structure of the kinase domain of human TRAF2 and NCK-interacting protein kinase
Summary for 5CWZ
| Entry DOI | 10.2210/pdb5cwz/pdb |
| Descriptor | TRAF2 and NCK-interacting protein kinase (2 entities in total) |
| Functional Keywords | kinase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 3 |
| Total formula weight | 105228.98 |
| Authors | Ohbayashi, N.,Kukimoto-Niino, M.,Yamada, T.,Shirouzu, M. (deposition date: 2015-07-28, release date: 2016-07-27, Last modification date: 2023-11-08) |
| Primary citation | Masuda, M.,Uno, Y.,Ohbayashi, N.,Ohata, H.,Mimata, A.,Kukimoto-Niino, M.,Moriyama, H.,Kashimoto, S.,Inoue, T.,Goto, N.,Okamoto, K.,Shirouzu, M.,Sawa, M.,Yamada, T. TNIK inhibition abrogates colorectal cancer stemness Nat Commun, 7:12586-12586, 2016 Cited by PubMed: 27562646DOI: 10.1038/ncomms12586 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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