PDB: 5689 件ウェブページステータス検索Chemie searchBIRD

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7Q1R	A de novo designed homo-dimeric antiparallel coiled coil apCC-Di 分子名称: ETHANOL, SODIUM ION, apCC-Di 著者 Shanmugaratnam, S, Rhys, G.G, Dawson, W.M, Woolfson, D.N, Hocker, B. 登録日 2021-10-20 公開日 2022-07-20 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 De novo designed peptides for cellular delivery and subcellular localisation. Nat.Chem.Biol., 18, 2022
7Q1S	A de novo designed hetero-dimeric antiparallel coiled coil apCC-Di-AB_var 分子名称: 1,2-ETHANEDIOL, apCC-Di-A_var, apCC-Di-B_var 著者 Shanmugaratnam, S, Rhys, G.G, Dawson, W.M, Woolfson, D.N, Hocker, B. 登録日 2021-10-20 公開日 2022-07-20 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.99 Å) 主引用文献 De novo designed peptides for cellular delivery and subcellular localisation. Nat.Chem.Biol., 18, 2022
7Q1T	A de novo designed hetero-dimeric antiparallel coiled coil apCC-Di-AB 分子名称: N-PROPANOL, SULFATE ION, apCC-Di-A, ... 著者 Shanmugaratnam, S, Rhys, G.G, Dawson, W.M, Woolfson, D.N, Hocker, B. 登録日 2021-10-20 公開日 2022-07-20 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 De novo designed peptides for cellular delivery and subcellular localisation. Nat.Chem.Biol., 18, 2022
5C2N	The de novo evolutionary emergence of a symmetrical protein is shaped by folding constraints 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta propeller 著者 Smock, R.G, Yadid, I, Dym, O, Clarke, J, Tawfik, D.S. 登録日 2015-06-16 公開日 2016-01-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.65 Å) 主引用文献 De Novo Evolutionary Emergence of a Symmetrical Protein Is Shaped by Folding Constraints. Cell, 164, 2016
7R1E	Mosquitocidal Cry11Ba determined at pH 10.4 from naturally-occurring nanocrystals by Serial femtosecond crystallography 分子名称: GLYCEROL, Pesticidal crystal protein Cry11Ba 著者 Colletier, J.-P, Sawaya, M.R, Schibrowsky, N.A, Cascio, D, Rodriguez, J.A. 登録日 2022-02-02 公開日 2022-07-27 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 De novo determination of mosquitocidal Cry11Aa and Cry11Ba structures from naturally-occurring nanocrystals. Nat Commun, 13, 2022
8URE	CryoEM Structure of Allosterically Switchable De Novo Protein sr312, in Open State with Effector Peptide 分子名称: Effector peptide cs221B, sr312 著者 Weidle, C, Skotheim, R. 登録日 2023-10-25 公開日 2024-08-14 最終更新日 2024-09-11 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 De novo design of allosterically switchable protein assemblies. Nature, 632, 2024
6WXO	De novo TIM barrel-ferredoxin fold fusion homodimer with 2-histidine 2-glutamate centre TFD-HE 分子名称: GLYCEROL, SULFATE ION, TFD-HE 著者 Caldwell, S.J, Zeymer, C, Haydon, I.C, Huang, P, Hilvert, D, Baker, D. 登録日 2020-05-11 公開日 2020-11-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion. Proc.Natl.Acad.Sci.USA, 117, 2020
7UEK	Crystal structure of a de novo designed ovoid TIM barrel OT3 分子名称: OT3 著者 Chu, A.E, Fernandez, D, Huang, P.-S. 登録日 2022-03-21 公開日 2023-01-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 De Novo Design of a Highly Stable Ovoid TIM Barrel: Unlocking Pocket Shape towards Functional Design. Biodes Res, 2022, 2022
5BVL	Crystal structure of a de novo designed TIM-barrel 分子名称: designed TIM barrel sTIM11 著者 Feldmeier, K, Hocker, B. 登録日 2015-06-05 公開日 2015-11-18 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.992 Å) 主引用文献 De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy. Nat.Chem.Biol., 12, 2016
6WXP	De novo TIM barrel-ferredoxin fold fusion homodimer with 4-glutamate centre TFD-EE 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, TFD-EE 著者 Caldwell, S.J, Zeymer, C, Haydon, I.C, Huang, P, Hilvert, D, Baker, D. 登録日 2020-05-11 公開日 2020-11-25 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion. Proc.Natl.Acad.Sci.USA, 117, 2020
6VG7	De novo designed Rossmann fold protein ROS2_49223 分子名称: De novo designed protein RO2_25 著者 Pan, X, Zhang, Y, Kelly, M, Kortemme, T. 登録日 2020-01-07 公開日 2020-08-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Expanding the space of protein geometries by computational design of de novo fold families. Science, 369, 2020
6VGA	De novo designed Rossmann fold protein ROS2_835 分子名称: De novo designed protein RO2_1 著者 Pan, X, Zhang, Y, Kelly, M, Kortemme, T. 登録日 2020-01-07 公開日 2020-08-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Expanding the space of protein geometries by computational design of de novo fold families. Science, 369, 2020
6VGB	De novo designed Rossmann fold protein ROS2_36830 分子名称: De novo designed protein RO2_20 著者 Pan, X, Zhang, Y, Kelly, M, Kortemme, T. 登録日 2020-01-07 公開日 2020-08-19 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Expanding the space of protein geometries by computational design of de novo fold families. Science, 369, 2020
7UR7	17_bp_sh3, a small beta-barrel de novo designed protein 分子名称: 17_bp_sh3 著者 Bera, A.K, Kim, D, Baker, D. 登録日 2022-04-21 公開日 2023-03-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.21 Å) 主引用文献 De novo design of small beta barrel proteins. Proc.Natl.Acad.Sci.USA, 120, 2023
7UR8	170_h_ob, a small beta-barrel de novo designed protein 分子名称: 170_h_ob 著者 Bera, A.K, Kim, D, Baker, D. 登録日 2022-04-21 公開日 2023-03-22 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 De novo design of small beta barrel proteins. Proc.Natl.Acad.Sci.USA, 120, 2023
8UAO	DpHF18 filament 分子名称: DpHF18 著者 Lynch, E.M, Shen, H, Kollman, J.M, Baker, D. 登録日 2023-09-21 公開日 2024-04-10 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 De novo design of pH-responsive self-assembling helical protein filaments. Nat Nanotechnol, 19, 2024
8UB3	DpHF7 filament 分子名称: DpHF7 filament 著者 Lynch, E.M, Farrell, D, Shen, H, Kollman, J.M, DiMaio, F, Baker, D. 登録日 2023-09-22 公開日 2024-04-10 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 De novo design of pH-responsive self-assembling helical protein filaments. Nat Nanotechnol, 19, 2024
6DG6	Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic 分子名称: Neoleukin-2/15 著者 Jude, K.M, Silva, D.-A, Yu, S, Baker, D, Garcia, K.C. 登録日 2018-05-16 公開日 2019-01-16 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 De novo design of potent and selective mimics of IL-2 and IL-15. Nature, 565, 2019
6DG5	Structure of a de novo designed Interleukin-2/Interleukin-15 mimetic complex with IL-2Rb and IL-2Rg 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit gamma, ... 著者 Jude, K.M, Silva, D.-A, Yu, S, Baker, D, Garcia, K.C. 登録日 2018-05-16 公開日 2019-01-16 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.516 Å) 主引用文献 De novo design of potent and selective mimics of IL-2 and IL-15. Nature, 565, 2019
8SK7	Cryo-EM structure of designed Influenza HA binder, HA_20, bound to Influenza HA (Strain: Iowa43) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HA_20 minibinder (RFdiffusion-designed), ... 著者 Borst, A.J, Bennett, N.R. 登録日 2023-04-18 公開日 2023-06-14 最終更新日 2023-09-13 実験手法 ELECTRON MICROSCOPY (2.93 Å) 主引用文献 De novo design of protein structure and function with RFdiffusion. Nature, 620, 2023
6UU0	E. coli sigma-S transcription initiation complex with a 3-nt RNA and a mismatching GTP ("Fresh" crystal soaked with GTP for 1 hour) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zuo, Y, De, S, Steitz, T.A. 登録日 2019-10-30 公開日 2020-08-26 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UU8	E. coli mutant sigma-S transcription initiation complex with a 7-nt RNA ("Fresh" mutant crystal soaked with GTP, UTP, and CTP for 30 minutes) 分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zuo, Y, De, S, Steitz, T.A. 登録日 2019-10-30 公開日 2020-08-26 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (4.4 Å) 主引用文献 Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
6UTW	E. coli sigma-S transcription initiation complex with a 4-nt RNA ("Fresh" crystal) 分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Zuo, Y, De, S, Steitz, T.A. 登録日 2019-10-30 公開日 2020-08-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.854 Å) 主引用文献 Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
8UBG	DpHF19 filament 分子名称: DpHF19,Green fluorescent protein (Fragment) 著者 Lynch, E.M, Shen, H, Kollman, J.M, Baker, D. 登録日 2023-09-22 公開日 2024-04-10 最終更新日 2024-08-07 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 De novo design of pH-responsive self-assembling helical protein filaments. Nat Nanotechnol, 19, 2024
8BL3	De novo single-chain immunoglobulin dimer scIg12 分子名称: GLYCEROL, scIg12 著者 Nadal, M, Roel-Touris, J, Marcos, E. 登録日 2022-11-09 公開日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Single-chain dimers from de novo immunoglobulins as robust scaffolds for multiple binding loops. Nat Commun, 14, 2023

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