6WXP

De novo TIM barrel-ferredoxin fold fusion homodimer with 4-glutamate centre TFD-EE

Summary for 6WXP

Entry DOI	10.2210/pdb6wxp/pdb
Related	4PWW 6WVS 6WXO
Descriptor	TFD-EE, CALCIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	tim barrel, ferredoxin fold, homodimeric fusion, de novo protein, symmetric fusion protein, metal binding
Biological source	synthetic construct
Total number of polymer chains	6
Total formula weight	113874.09
Authors	Caldwell, S.J.,Zeymer, C.,Haydon, I.C.,Huang, P.,Hilvert, D.,Baker, D. (deposition date: 2020-05-11, release date: 2020-11-25, Last modification date: 2024-04-03)
Primary citation	Caldwell, S.J.,Haydon, I.C.,Piperidou, N.,Huang, P.S.,Bick, M.J.,Sjostrom, H.S.,Hilvert, D.,Baker, D.,Zeymer, C. Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion. Proc.Natl.Acad.Sci.USA, 117:30362-30369, 2020 Cited by PubMed: 33203677 DOI: 10.1073/pnas.2008535117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation