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6WXO

De novo TIM barrel-ferredoxin fold fusion homodimer with 2-histidine 2-glutamate centre TFD-HE

Summary for 6WXO
Entry DOI10.2210/pdb6wxo/pdb
Related4PWW 6WVS 6WXP
DescriptorTFD-HE, GLYCEROL, SULFATE ION, ... (4 entities in total)
Functional Keywordstim barrel, ferredoxin fold, homodimer, symmetric fusion, hyperstable, symmetric, de novo, repeat protein, de novo protein
Biological sourcesynthetic construct
Total number of polymer chains2
Total formula weight42404.55
Authors
Caldwell, S.J.,Zeymer, C.,Haydon, I.C.,Huang, P.,Hilvert, D.,Baker, D. (deposition date: 2020-05-11, release date: 2020-11-25, Last modification date: 2024-03-06)
Primary citationCaldwell, S.J.,Haydon, I.C.,Piperidou, N.,Huang, P.S.,Bick, M.J.,Sjostrom, H.S.,Hilvert, D.,Baker, D.,Zeymer, C.
Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion.
Proc.Natl.Acad.Sci.USA, 117:30362-30369, 2020
Cited by
PubMed: 33203677
DOI: 10.1073/pnas.2008535117
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.41 Å)
Structure validation

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