6WXO
De novo TIM barrel-ferredoxin fold fusion homodimer with 2-histidine 2-glutamate centre TFD-HE
Summary for 6WXO
Entry DOI | 10.2210/pdb6wxo/pdb |
Related | 4PWW 6WVS 6WXP |
Descriptor | TFD-HE, GLYCEROL, SULFATE ION, ... (4 entities in total) |
Functional Keywords | tim barrel, ferredoxin fold, homodimer, symmetric fusion, hyperstable, symmetric, de novo, repeat protein, de novo protein |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 42404.55 |
Authors | Caldwell, S.J.,Zeymer, C.,Haydon, I.C.,Huang, P.,Hilvert, D.,Baker, D. (deposition date: 2020-05-11, release date: 2020-11-25, Last modification date: 2024-03-06) |
Primary citation | Caldwell, S.J.,Haydon, I.C.,Piperidou, N.,Huang, P.S.,Bick, M.J.,Sjostrom, H.S.,Hilvert, D.,Baker, D.,Zeymer, C. Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion. Proc.Natl.Acad.Sci.USA, 117:30362-30369, 2020 Cited by PubMed: 33203677DOI: 10.1073/pnas.2008535117 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.41 Å) |
Structure validation
Download full validation report