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4Y1T
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Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes
分子名称: CALCIUM ION, Perforin-1
著者Conroy, P.J, Yagi, H, Whisstock, J.C, Norton, R.S.
登録日2015-02-09
公開日2015-09-02
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.666 Å)
主引用文献Structural Basis for Ca2+-mediated Interaction of the Perforin C2 Domain with Lipid Membranes.
J.Biol.Chem., 290, 2015
22GS
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HUMAN GLUTATHIONE S-TRANSFERASE P1-1 Y49F MUTANT
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE S-TRANSFERASE P1-1
著者Oakley, A.J.
登録日1998-03-10
公開日1999-03-23
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Thermodynamic description of the effect of the mutation Y49F on human glutathione transferase P1-1 in binding with glutathione and the inhibitor S-hexylglutathione.
J.Biol.Chem., 278, 2003
2A75
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Trypanosoma rangeli Sialidase In Complex With 2,3- Difluorosialic Acid (Covalent Intermediate)
分子名称: 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, SULFATE ION, sialidase
著者Amaya, M.F, Alzari, P.M, Buschiazzo, A.
登録日2005-07-04
公開日2005-11-22
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and Kinetic Analysis of Two Covalent Sialosyl-Enzyme Intermediates on Trypanosoma rangeli Sialidase.
J.Biol.Chem., 281, 2006
6FV6
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Monomer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state
分子名称: Aq128
著者Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H.
登録日2018-03-01
公開日2019-03-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Monomer structure of Aq128 in the outward-facing state
To Be Published
6FV8
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Dimer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state
分子名称: Aq128
著者Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H.
登録日2018-03-01
公開日2019-03-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Dimer structure of the MATE family multidrug resistance transporter Aq128 in the outward-facing state
To Be Published
2AH2
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Trypanosoma cruzi trans-sialidase in complex with 2,3-difluorosialic acid (covalent intermediate)
分子名称: 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, CHLORIDE ION, GLYCEROL, ...
著者Amaya, M.F, Watts, A.G, Damager, I, Wehenkel, A, Nguyen, T, Buschiazzo, A, Paris, G, Frasch, A.C, Withers, S.G, Alzari, P.M.
登録日2005-07-27
公開日2005-08-23
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase
Structure, 12, 2004
6FV7
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BU of 6fv7 by Molmil
Dimer structure of the MATE family multidrug resistance transporter Aq_128 from Aquifex aeolicus in the outward-facing state
分子名称: Aq128
著者Zhao, J, Safarian, S, Thielmann, Y, Xie, H, Wang, J, Michel, H.
登録日2018-03-01
公開日2019-03-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Dimer structure of Aq128 in the outward-facing state
To Be Published
5HKA
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Crystal structure of the CFTR inhibitory factor Cif bound to an amide inhibitor
分子名称: 5'-[2,6-dichloro-4-(propanoylamino)phenoxy]-2'-hydroxybiphenyl-4-carboxamide, CFTR inhibitory factor
著者Hvorecny, K.L, Madden, D.R.
登録日2016-01-13
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa.
J.Med.Chem., 59, 2016
5HKB
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Crystal structure of the CFTR inhibitory factor Cif bound to the inhibitor KB2115
分子名称: ACETATE ION, CFTR Inhibitory Factor (Cif), KB2115
著者Hvorecny, K.L, Madden, D.R.
登録日2016-01-13
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa.
J.Med.Chem., 59, 2016
5JIP
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Crystal structure of the Clostridium perfringens spore cortex lytic enzyme SleM
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cortical-lytic enzyme, MAGNESIUM ION
著者Chirgadze, D.Y, Christie, G, Ustok, F.I, Al-Riyami, B, Stott, K.
登録日2016-04-22
公開日2016-08-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of Clostridium perfringens SleM, a muramidase involved in cortical hydrolysis during spore germination.
Proteins, 84, 2016
5HK9
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Crystal structure of the CFTR inhibitory factor Cif bound to a urea inhibitor
分子名称: CFTR inhibitory factor, N-(4-{[4'-(carbamoylamino)-6-hydroxybiphenyl-3-yl]oxy}-3,5-dichlorophenyl)propanamide
著者Hvorecny, K.L, Madden, D.R.
登録日2016-01-13
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Rational Design of Potent and Selective Inhibitors of an Epoxide Hydrolase Virulence Factor from Pseudomonas aeruginosa.
J.Med.Chem., 59, 2016
5JYC
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Crystal structure of the E153Q mutant of the CFTR inhibitory factor Cif containing the adducted 14,15-EET hydrolysis intermediate
分子名称: (5~{Z},11~{Z},14~{R},15~{R})-14,15-bis(oxidanyl)icosa-5,8,11-trienoic acid, CFTR inhibitory factor
著者Hvorecny, K.L, Madden, D.R.
登録日2016-05-13
公開日2017-01-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Pseudomonas aeruginosa sabotages the generation of host proresolving lipid mediators.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5IUM
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BU of 5ium by Molmil
Crystal structure of phosphorylated DesKC
分子名称: GLYCEROL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Trajtenberg, F, Buschiazzo, A.
登録日2016-03-18
公開日2016-12-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.162 Å)
主引用文献Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action.
Elife, 5, 2016
7NB6
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BU of 7nb6 by Molmil
Structure of the autoinducer-2 exporter TqsA from E. coli
分子名称: AI-2 transport protein TqsA
著者Khera, R, Xie, H, Michel, H.
登録日2021-01-25
公開日2022-05-11
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of pentameric autoinducer-2 exporter from Escherichia coli reveal its transport mechanism.
Embo J., 41, 2022
3R6Q
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A triclinic-lattice structure of aspartase from Bacillus sp. YM55-1
分子名称: Aspartase, CALCIUM ION
著者Fibriansah, G, Puthan Veetil, V, Poelarends, G.J, Thunnissen, A.-M.W.H.
登録日2011-03-22
公開日2011-07-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for the catalytic mechanism of aspartate ammonia lyase.
Biochemistry, 50, 2011
4WD6
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Crystal Structure of DIM-1 metallo-beta-lactamase
分子名称: Metallo-beta-lactamase, ZINC ION
著者Booth, M.P.S, Kosmopoulou, M, Spencer, J.
登録日2014-09-07
公開日2014-09-17
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal Structure of DIM-1 metallo-beta-lactamase
To Be Published
3RLC
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Crystal structure of the read-through domain from bacteriophage Qbeta A1 protein, hexagonal crystal form
分子名称: A1 protein, TETRAETHYLENE GLYCOL
著者Rumnieks, J, Tars, K.
登録日2011-04-19
公開日2011-09-28
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the read-through domain from bacteriophage Qbeta A1 protein
Protein Sci., 20, 2011
3R6Y
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Crystal structure of chymotrypsin-treated aspartase from Bacillus sp. YM55-1
分子名称: Aspartase, CALCIUM ION
著者Fibriansah, G, Puthan Veetil, V, Poelarends, G.J, Thunnissen, A.-M.W.H.
登録日2011-03-22
公開日2011-07-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the catalytic mechanism of aspartate ammonia lyase.
Biochemistry, 50, 2011
4WAC
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Crystal Structure of TarM
分子名称: 1,2-ETHANEDIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ...
著者Koc, C, Stehle, T, Xia, G, Peschel, A.
登録日2014-08-29
公開日2015-02-25
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Enzymatic Analysis of TarM Glycosyltransferase from Staphylococcus aureus Reveals an Oligomeric Protein Specific for the Glycosylation of Wall Teichoic Acid.
J.Biol.Chem., 290, 2015
4WAD
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Crystal Structure of TarM with UDP-GlcNAc
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Glycosyl transferase, ...
著者Koc, C, Stehle, T, Xia, G, Peschel, A.
登録日2014-08-29
公開日2015-02-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and Enzymatic Analysis of TarM Glycosyltransferase from Staphylococcus aureus Reveals an Oligomeric Protein Specific for the Glycosylation of Wall Teichoic Acid.
J.Biol.Chem., 290, 2015
6Q84
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Crystal structure of RanGTP-Pdr6-eIF5A export complex
分子名称: Eukaryotic translation initiation factor 5A-1, GTP-binding nuclear protein Ran, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Aksu, M, Trakhanov, S, Vera-Rodriguez, A, Gorlich, D.
登録日2018-12-14
公開日2019-05-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Structural basis for the nuclear import and export functions of the biportin Pdr6/Kap122.
J.Cell Biol., 218, 2019
7ZQT
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Helicobacter pylori adhesin BabA bound to neutralising human antibody.
分子名称: 1,2-ETHANEDIOL, Adhesin binding fucosylated histo-blood group antigen, GLYCEROL, ...
著者Moonens, K, Boren, T.
登録日2022-05-03
公開日2023-05-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Helicobacter pylori adhesin BabA bound to neutralising human antibody.
To Be Published
4WXH
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Carminomycin-4-O-methyltransferase (DnrK) variant (298Ser insert) in complex with S-adenosyl-L-homocysteine (SAH) and aclacinomycin T
分子名称: (2R,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL, Carminomycin 4-O-methyltransferase DnrK, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Metsa-Ketela, M, Niiranen, L.
登録日2014-11-13
公開日2015-07-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Divergent evolution of an atypical S-adenosyl-l-methionine-dependent monooxygenase involved in anthracycline biosynthesis.
Proc.Natl.Acad.Sci.USA, 112, 2015
4ZEJ
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Crystal Structure of DIM-1 Metallo-beta-Lactamase exposed to Ceftazidime
分子名称: CHLORIDE ION, Metallo-beta-lactamase, ZINC ION
著者Booth, M.P.S, Kosmopoulou, M, Spencer, J.
登録日2015-04-20
公開日2015-05-27
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Crystal Stricture of DIM-1 Metallo-beta-Lactamase
To Be Published
5AC3
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Crystal structure of PAM12A
分子名称: ACETIC ACID, CADMIUM ION, PEPTIDE AMIDASE
著者Wu, B, Wijma, H.J, Song, L, Rozeboom, H.J, Poloni, C, Tian, Y, Arif, M.I, Nuijens, T, Quadflieg, P.J.L.M, Szymanski, W, Feringa, B.L, Janssen, D.B.
登録日2015-08-11
公開日2016-07-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Versatile Peptide C-Terminal Functionalization Via a Computationally Peptide Amidase
Acs Catalysis, 2016

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