Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2AH2

Trypanosoma cruzi trans-sialidase in complex with 2,3-difluorosialic acid (covalent intermediate)

Replaces:  1S0K
Summary for 2AH2
Entry DOI10.2210/pdb2ah2/pdb
Related2A75 2AGS
Descriptortrans-sialidase, CHLORIDE ION, 5-acetamido-3,5-dideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid, ... (6 entities in total)
Functional Keywordstransglycosidase, covalent intermediate, trypanosoma cruzi, sialic acid, hydrolase
Biological sourceTrypanosoma cruzi
Total number of polymer chains1
Total formula weight72088.35
Authors
Amaya, M.F.,Watts, A.G.,Damager, I.,Wehenkel, A.,Nguyen, T.,Buschiazzo, A.,Paris, G.,Frasch, A.C.,Withers, S.G.,Alzari, P.M. (deposition date: 2005-07-27, release date: 2005-08-23, Last modification date: 2021-10-20)
Primary citationAmaya, M.F.,Watts, A.G.,Damager, I.,Wehenkel, A.,Nguyen, T.,Buschiazzo, A.,Paris, G.,Frasch, A.C.,Withers, S.G.,Alzari, P.M.
Structural Insights into the Catalytic Mechanism of Trypanosoma cruzi trans-Sialidase
Structure, 12:775-784, 2004
Cited by
PubMed: 15130470
DOI: 10.1016/j.str.2004.02.036
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon