PDB: 159 件ウェブページステータス検索Chemie searchBIRD

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6SZ7	Crystal structure of YTHDC1 with fragment 5 (DHU_DC1_066) 分子名称: 5,6,7,8-tetrahydro-4~{a}~{H}-quinazoline-2,4-dione, SULFATE ION, YTH domain-containing protein 1 著者 Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. 登録日 2019-10-02 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.31 Å) 主引用文献 Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments. Acs Chem.Biol., 15, 2020
6SZ3	Crystal structure of YTHDC1 with fragment 4 (DHU_DC1_158) 分子名称: SULFATE ION, YTH domain-containing protein 1, ~{N}-methyl-5,6,7,8-tetrahydroquinolin-4-amine 著者 Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. 登録日 2019-10-01 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments. Acs Chem.Biol., 15, 2020
6SZ2	Crystal structure of YTHDC1 with fragment 3 (DHU_DC1_149) 分子名称: SULFATE ION, YTH domain-containing protein 1, ~{N}-methyl-1,6-naphthyridin-4-amine 著者 Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. 登録日 2019-10-01 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments. Acs Chem.Biol., 15, 2020
6SZ1	Crystal structure of YTHDC1 with fragment 2 (DHU_DC1_140) 分子名称: SULFATE ION, YTH domain-containing protein 1, ~{N}-methylquinazolin-4-amine 著者 Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. 登録日 2019-10-01 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments. Acs Chem.Biol., 15, 2020
6SYZ	Crystal structure of YTHDC1 with fragment 1 (DHU_DC1_141) 分子名称: SULFATE ION, YTH domain-containing protein 1, ~{N}-methylthieno[3,2-d]pyrimidin-4-amine 著者 Bedi, R.K, Huang, D, Sledz, P, Caflisch, A. 登録日 2019-10-01 公開日 2020-03-04 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Selectively Disrupting m6A-Dependent Protein-RNA Interactions with Fragments. Acs Chem.Biol., 15, 2020
6RT7	The YTH domain of YTHDC1 protein in complex with Gm6ACU oligonucleotide 分子名称: RNA (5'-R(*(6MZ)P*C)-3'), SULFATE ION, YTH domain-containing protein 1 著者 Bedi, R, Sledz, P, Caflisch, A. 登録日 2019-05-22 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif. J Chem Theory Comput, 15, 2019
6RT6	The YTH domain of YTHDC1 protein in complex with GGm6AC oligonucleotide 分子名称: RNA (5'-R(*(6MZ)P*C)-3'), SULFATE ION, YTH domain-containing protein 1 著者 Bedi, R, Sledz, P, Caflisch, A. 登録日 2019-05-22 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.461 Å) 主引用文献 Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif. J Chem Theory Comput, 15, 2019
6RT5	The YTH domain of YTHDC1 protein in complex with Gm6AC oligonucleotide 分子名称: RNA (5'-R(*(6MZ)P*C)-3'), SULFATE ION, YTH domain-containing protein 1 著者 Bedi, R, Sledz, P, Caflisch, A. 登録日 2019-05-22 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.303 Å) 主引用文献 Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif. J Chem Theory Comput, 15, 2019
6RT4	The YTH domain of YTHDC1 protein in complex with m6ACU oligonucleotide 分子名称: RNA (5'-R(*(6MZ)P*C)-3'), SULFATE ION, YTH domain-containing protein 1 著者 Bedi, R, Sledz, P, Caflisch, A. 登録日 2019-05-22 公開日 2019-11-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif. J Chem Theory Comput, 15, 2019
6LR2	SOLUTION STRUCTURE OF THE YTH DOMAIN IN YTH DOMAIN-2 CONTAINING PROTEIN 2 分子名称: YTH domain containing protein 2 (YTHDC2) 著者 Muto, Y, Kobayashi, N, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2020-01-15 公開日 2021-01-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 SOLUTION STRUCTURE OF THE YTH DOMAIN IN YTH DOMAIN-CONTAINING PROTEIN 2 TO BE PUBLISHED
6K6U	Crystal structure of the human YTHDC2 YTH domain 分子名称: 3'-5' RNA helicase YTHDC2 著者 Ma, C, Liao, S, Xu, C. 登録日 2019-06-04 公開日 2019-12-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Crystal structure of human YTHDC2 YTH domain. Biochem.Biophys.Res.Commun., 518, 2019
6FPX	Structure of S. pombe Mmi1 in complex with 11-mer RNA 分子名称: GLYCEROL, RNA (5'-R(P*UP*UP*UP*AP*AP*AP*CP*CP*UP*A)-3'), YTH domain-containing protein mmi1 著者 Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A. 登録日 2018-02-12 公開日 2018-05-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding. J. Biol. Chem., 293, 2018
6FPQ	Structure of S. pombe Mmi1 in complex with 7-mer RNA 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, RNA (5'-R(*UP*UP*AP*AP*AP*CP*C)-3'), YTH domain-containing protein mmi1 著者 Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A. 登録日 2018-02-11 公開日 2018-05-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding. J. Biol. Chem., 293, 2018
6FPP	Structure of S. pombe Mmi1 分子名称: GLYCEROL, MAGNESIUM ION, YTH domain-containing protein mmi1 著者 Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A. 登録日 2018-02-11 公開日 2018-05-09 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding. J. Biol. Chem., 293, 2018
5ZUU	Crystal structure of AtCPSF30 YTH domain in complex with 10mer m6A-modified RNA 分子名称: 30-kDa cleavage and polyadenylation specificity factor 30, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, GLYCEROL, ... 著者 Wu, B, Nie, H, Li, S, Patel, D.J. 登録日 2018-05-08 公開日 2019-05-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 CPSF30-L-mediated recognition of mRNA m6A modification controls alternative polyadenylation of nitrate signaling-related gene transcripts in Arabidopsis. Mol Plant, 2021
5O8M	Crystal structure of the MmI1 YTH domain 分子名称: GLYCEROL, YTH domain-containing protein mmi1 著者 Brettschneider, J, Verdel, A, Kadlec, J. 登録日 2017-06-13 公開日 2018-04-25 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation. EMBO J., 36, 2017
5HFZ	Mmi1 YTH domain 分子名称: YTH domain-containing protein mmi1 著者 Chatterjee, D, Goldgur, Y, Shuman, S. 登録日 2016-01-07 公開日 2016-02-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast. Rna, 22, 2016
5H8A	Mmi1 YTH domain 分子名称: YTH domain-containing protein mmi1 著者 Chatterjee, D, Goldgur, Y, Shuman, S. 登録日 2015-12-23 公開日 2016-01-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.751 Å) 主引用文献 Transcription of lncRNA prt, clustered prt RNA sites for Mmi1 binding, and RNA polymerase II CTD phospho-sites govern the repression of pho1 gene expression under phosphate-replete conditions in fission yeast. Rna, 22, 2016
5EIP	apo-structure of YTH domain of SpMmi1 分子名称: YTH domain-containing protein mmi1 著者 Wu, B.X, Xu, J.H, Su, S.C, Ma, J.B. 登録日 2015-10-30 公開日 2016-01-27 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Structural insights into the specific recognition of DSR by the YTH domain containing protein Mmi1 Biochem. Biophys. Res. Commun., 491, 2017
5EIM	YTH domain-containing protein mmi1 and RNA complex 分子名称: RNA (5'-R(*AP*UP*UP*AP*AP*AP*CP*A)-3'), YTH domain-containing protein mmi1 著者 Wu, B.X, Xu, J.H, Su, S.C, Ma, J.B. 登録日 2015-10-30 公開日 2016-01-27 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 Structural insights into the specific recognition of DSR by the YTH domain containing protein Mmi1 Biochem. Biophys. Res. Commun., 491, 2017
5DNP	Crystal structure of Mmi1 YTH domain 分子名称: PHOSPHATE ION, YTH domain-containing protein mmi1 著者 Wang, C.Y, Zhu, Y.W, Shi, Y.Y, Wu, J.H. 登録日 2015-09-10 公開日 2016-04-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A novel RNA-binding mode of the YTH domain reveals the mechanism for recognition of determinant of selective removal by Mmi1 Nucleic Acids Res., 44, 2016
5DNO	Crystal structure of Mmi1 YTH domain complex with RNA 分子名称: RNA (5'-R(*CP*UP*UP*AP*AP*AP*C)-3'), YTH domain-containing protein mmi1 著者 Wang, C.Y, Zhu, Y.W, Wu, J.H, Shi, Y.Y. 登録日 2015-09-10 公開日 2016-04-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A novel RNA-binding mode of the YTH domain reveals the mechanism for recognition of determinant of selective removal by Mmi1 Nucleic Acids Res., 44, 2016
4WQN	Crystal structure of N6-methyladenosine RNA reader YTHDF2 分子名称: 1,2-ETHANEDIOL, GLYCEROL, YTH domain-containing family protein 2 著者 Zhu, T, Roundtree, I.A, Wang, P, Wang, X, Wang, L, Sun, C, Tian, Y, Li, J, He, C, Xu, Y. 登録日 2014-10-22 公開日 2014-11-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.121 Å) 主引用文献 Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine. Cell Res., 24, 2014
4U8T	Crystal structure of YTH domain of Zygosaccharomyces rouxii MRB1 protein in complex with N6-Methyladenosine RNA 分子名称: RNA (5'-R(*AP*GP*GP*(6MZ)P*CP*AP*U)-3'), ZYRO0G01672p 著者 Luo, S, Tong, L. 登録日 2014-08-04 公開日 2014-09-10 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain. Proc.Natl.Acad.Sci.USA, 111, 2014
4RDO	Structure of YTH-YTHDF2 in the free state 分子名称: SULFATE ION, YTH domain-containing family protein 2 著者 Li, F.D, Zhao, D.B, Wu, J.H, Shi, Y.Y. 登録日 2014-09-19 公開日 2014-12-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structure of the YTH domain of human YTHDF2 in complex with an m(6)A mononucleotide reveals an aromatic cage for m(6)A recognition. Cell Res., 24, 2014

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