6RT7

The YTH domain of YTHDC1 protein in complex with Gm6ACU oligonucleotide

Summary for 6RT7

• Entry DOI: 10.2210/pdb6rt7/pdb
• Descriptor: RNA (5'-R(*(6MZ)P*C)-3'), YTH domain-containing protein 1, SULFATE ION, ... (4 entities in total)
• Functional Keywords: protein-rna interaction, epitranscriptomics, rna binding protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 40637.63

Authors

Bedi, R.,Sledz, P.,Caflisch, A. (deposition date: 2019-05-22, release date: 2019-11-27, Last modification date: 2024-01-24)

• Primary citation: Li, Y.,Bedi, R.K.,Wiedmer, L.,Huang, D.,Sledz, P.,Caflisch, A.; Flexible Binding of m6A Reader Protein YTHDC1 to Its Preferred RNA Motif.; J Chem Theory Comput, 15:7004-7014, 2019; PubMed: 31670957; DOI: 10.1021/acs.jctc.9b00987

Experimental method

X-RAY DIFFRACTION (1.73 Å)