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7LEQ
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BU of 7leq by Molmil
Structure of importin a2 bound to p50 NLS
分子名称: Importin subunit alpha-1, Nuclear factor NF-kappa-B p105 subunit
著者Florio, T.J, Lokareddy, R.K, Cingolani, G.
登録日2021-01-14
公開日2022-01-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Differential recognition of canonical NF-kappa B dimers by Importin alpha 3.
Nat Commun, 13, 2022
5V5O
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BU of 5v5o by Molmil
Structure of NLS2K of influenza A virus nucleoprotein bound to importin alpha
分子名称: Importin subunit alpha-1, Nucleoprotein
著者Sankhala, R.S, Lokareddy, R.K, Cingolani, G.
登録日2017-03-14
公開日2018-03-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.243 Å)
主引用文献Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin alpha isoforms.
Sci Rep, 7, 2017
4XZR
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BU of 4xzr by Molmil
Structure of yeast importin a bound to the membrane protein Nuclear Localization Signal sequence of INM protein Heh1
分子名称: Importin subunit alpha, Inner nuclear membrane protein SRC1
著者Lokareddy, R.K, Cingolani, G.
登録日2015-02-04
公開日2015-06-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Distinctive Properties of the Nuclear Localization Signals of Inner Nuclear Membrane Proteins Heh1 and Heh2.
Structure, 23, 2015
4EVP
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BU of 4evp by Molmil
Crystal Structure of Mouse Catenin beta-59 in 7.2M urea
分子名称: Catenin beta-1, UREA
著者Wang, C, Zhang, G.Y.
登録日2012-04-26
公開日2013-05-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.255 Å)
主引用文献Crystal Structure of Mouse Catenin beta-59 in 7.2M urea
TO BE PUBLISHED
7L04
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BU of 7l04 by Molmil
Crystal Structure of Adeno-Associated Virus Porcine Origin capsid protein in complex with Importin-alpha 2
分子名称: Importin subunit alpha-1, VP1
著者Hoad, M, Forwood, J.
登録日2020-12-11
公開日2021-02-24
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal Structure of Adeno-Associated Virus Porcine Origin capsid protein in complex with Importin-alpha 2
To Be Published
7VPS
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BU of 7vps by Molmil
Crystal structure of the ARM domain of C. glabrata importin alpha
分子名称: Importin subunit alpha
著者Tan, L, Im, Y.J.
登録日2021-10-17
公開日2022-09-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural basis for activation of fungal sterol receptor Upc2 and azole resistance.
Nat.Chem.Biol., 18, 2022
3RZ9
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BU of 3rz9 by Molmil
Mouse importin alpha-Ku80 NLS peptide complex
分子名称: Importin subunit alpha-2, Ku80 NLS peptide
著者Barros, A.C, Takeda, A.A.S, Fontes, M.R.M.
登録日2011-05-11
公開日2011-08-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural basis of importin-alpha-mediated nuclear transport for Ku70 and Ku80.
J.Mol.Biol., 412, 2011
6D7N
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BU of 6d7n by Molmil
Crystal structure of the W357R/W399R Importin alpha mutant
分子名称: 1,2-ETHANEDIOL, Peroxidase,Importin subunit alpha-1
著者Pedersen, L.C, London, R.E, Gabel, S.A.
登録日2018-04-25
公開日2019-03-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Variations in nuclear localization strategies among pol X family enzymes.
Traffic, 2018
4BPL
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BU of 4bpl by Molmil
rice importin_alpha in complex with nucleoplasmin NLS
分子名称: IMPORTIN SUBUNIT ALPHA-1A, NUCLEOPLASMIN NLS
著者Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
登録日2013-05-27
公開日2014-02-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of Interaction of Bipartite Nuclear Localization Signal from Agrobacterium Vird2 with Rice Importin-Alpha
Mol.Plant, 7, 2014
3UKZ
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BU of 3ukz by Molmil
Mouse importin alpha: mouse CBP80 cNLS complex
分子名称: Importin subunit alpha-2, Nuclear cap-binding protein subunit 1
著者Marfori, M, Forwood, J.K, Lonhienne, T.G, Kobe, B.
登録日2011-11-10
公開日2012-10-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis of High-Affinity Nuclear Localization Signal Interactions with Importin-alpha
Traffic, 13, 2012
7M60
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BU of 7m60 by Molmil
Structure of Mouse Importin alpha MLH1-S467A NLS Peptide Complex
分子名称: DNA mismatch repair protein Mlh1 NLS peptide, Importin subunit alpha-1
著者De Oliveira, H.C, Da Silva, T.D, Fukuda, C.A, Fontes, M.R.M.
登録日2021-03-25
公開日2021-07-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha.
Biochem.J., 478, 2021
7TMX
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BU of 7tmx by Molmil
Structure of Mouse Importin alpha NEIL1 NLS Peptide Complex
分子名称: Importin subunit alpha-1, Nuclear Localization Signal from Endonuclease 8-like 1
著者Moraes, I.R, de Oliveira, H.C, Fontes, M.R.M.
登録日2022-01-20
公開日2023-08-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha.
Biochim Biophys Acta Proteins Proteom, 1872, 2023
5B56
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BU of 5b56 by Molmil
Crystal structure of HIV-1 VPR C-Terminal domain and DIBB-M-Importin-Alpha2 complex
分子名称: Importin subunit alpha-1, Protein Vpr
著者Miyatake, H, Sanjoh, A, Matusda, G, Murakami, T, Murakami, H, Hagiwara, K, Yokoyama, M, Sato, H, Miyamoto, Y, Dohmae, N, Aida, Y.
登録日2016-04-25
公開日2016-06-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular Mechanism of HIV-1 Vpr for Binding to Importin-alpha
J.Mol.Biol., 428, 2016
4ZDU
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BU of 4zdu by Molmil
Crystal structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein
分子名称: Importin subunit alpha-1, Peptide from Nucleoprotein
著者Nakada, R, Hirano, H, Matsuura, Y.
登録日2015-04-19
公開日2015-10-21
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of importin-alpha bound to a non-classical nuclear localization signal of the influenza A virus nucleoprotein
Sci Rep, 5, 2015
8TUV
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BU of 8tuv by Molmil
Merkel Cell Polyomavirus LTA NLSm bound to importin alpha 2
分子名称: 30S ribosomal protein S11, Importin subunit alpha-1, SER-ARG-LYS-ARG-LYS-PHE
著者Cross, E.M, Forwood, J.K, Alvisi, G.
登録日2023-08-17
公開日2024-02-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A functional and structural comparative analysis of large tumor antigens reveals evolution of different importin alpha-dependent nuclear localization signals.
Protein Sci., 33, 2024
2YNR
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BU of 2ynr by Molmil
mImp_alphadIBB_B54NLS
分子名称: B54NLS, IMPORTIN SUBUNIT ALPHA
著者Chang, C.-W, Counago, R.L.M, Williams, S.J, Boden, M, Kobe, B.
登録日2012-10-18
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Rice Importin-Alpha and Structural Basis of its Interaction with Plant-Specific Nuclear Localization Signals.
Plant Cell, 24, 2012
6WX8
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BU of 6wx8 by Molmil
SOX2 bound to Importin-alpha 3
分子名称: Importin subunit alpha-3, SULFATE ION, Transcription factor SOX-2
著者Bikshapathi, J, Stewart, M, Forwood, J.K, Aragao, D, Roman, N.
登録日2020-05-10
公開日2020-10-28
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for nuclear import selectivity of pioneer transcription factor SOX2.
Nat Commun, 12, 2021
3ZIR
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BU of 3zir by Molmil
minor-site specific NLS (B141)
分子名称: B141NLS, IMPORTIN SUBUNIT ALPHA-2
著者Chang, C.-W, Counago, R.M, Williams, S.J, Kobe, B.
登録日2013-01-10
公開日2013-08-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Distinctive Conformation of Minor Site-Specific Nuclear Localization Signals Bound to Importin-Alpha
Traffic, 14, 2013
1Q1S
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BU of 1q1s by Molmil
Mouse Importin alpha- phosphorylated SV40 CN peptide complex
分子名称: Importin alpha-2 subunit, Large T antigen
著者Fontes, M.R.M, Teh, T, Toth, G, John, A, Pavo, I, Jans, D.A, Kobe, B.
登録日2003-07-22
公開日2004-03-30
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-alpha
Biochem.J., 375, 2003
4R10
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BU of 4r10 by Molmil
A conserved phosphorylation switch controls the interaction between cadherin and beta-catenin in vitro and in vivo
分子名称: 1,2-ETHANEDIOL, Cadherin-related hmr-1, Protein humpback-2, ...
著者Choi, H.-J, Loveless, T, Lynch, A, Bang, I, Hardin, J, Weis, W.I.
登録日2014-08-03
公開日2015-04-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A Conserved Phosphorylation Switch Controls the Interaction between Cadherin and beta-Catenin In Vitro and In Vivo
Dev.Cell, 33, 2015
6BVV
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BU of 6bvv by Molmil
Nipah virus W protein C-terminus in complex with Importin alpha 3
分子名称: Importin subunit alpha-3, Protein W
著者Smith, K.M, Tsimbalyuk, S, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-13
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
3NMX
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BU of 3nmx by Molmil
Crystal structure of APC complexed with Asef
分子名称: APC variant protein, Rho guanine nucleotide exchange factor 4
著者Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G.
登録日2010-06-22
公開日2011-07-06
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
5H43
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BU of 5h43 by Molmil
Structural and mechanistical studies of the nuclear import by Importin-alpha
分子名称: Histone acetyltransferase KAT8, Importin subunit alpha-1
著者Wang, R, Li, Y.
登録日2016-10-28
公開日2017-10-25
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural insights into the nuclear import of the histone acetyltransferase males-absent-on-the-first by importin alpha 1
Traffic, 19, 2018
6BWB
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BU of 6bwb by Molmil
Hendra virus W protein C-terminus in complex with Importin alpha 3 crystal form 3
分子名称: Importin subunit alpha-3, Protein W
著者Tsimbalyuk, S, Smith, K.M, Edwards, M.R, Aragao, D, Cross, E.M, Basler, C.F, Forwood, J.K.
登録日2017-12-14
公開日2018-07-04
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses.
Nat Commun, 9, 2018
3L3Q
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BU of 3l3q by Molmil
Mouse importin alpha-pepTM NLS peptide complex
分子名称: CITRATE ANION, Importin subunit alpha-2, pepTM
著者Takeda, A.A.S, Kobe, B, Fontes, M.R.M.
登録日2009-12-17
公開日2010-04-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Probing the specificity of binding to the major nuclear localization sequence-binding site of importin-alpha using oriented peptide library screening.
J.Biol.Chem., 285, 2010

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