7R4D
| Bovine complex I in the presence of IM1761092, deactive class vi (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R4C
| Bovine complex I in the presence of IM1761092, deactive class v (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R48
| Bovine complex I in the presence of IM1761092, deactive class iv (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R47
| Bovine complex I in the presence of IM1761092, deactive class iii (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R46
| Bovine complex I in the presence of IM1761092, deactive class ii (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R45
| Bovine complex I in the presence of IM1761092, deactive class i (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R44
| Bovine complex I in the presence of IM1761092, active class iv (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R43
| Bovine complex I in the presence of IM1761092, active class iii (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R42
| Bovine complex I in the presence of IM1761092, active class ii (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7R41
| Bovine complex I in the presence of IM1761092, active class i (Composite map) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1-carbamimidoyl-3-[2-(3-chloranyl-4-iodanyl-phenyl)ethyl]guanidine, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-02-08 | 公開日 | 2023-02-08 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7QV7
| Cryo-EM structure of Hydrogen-dependent CO2 reductase. | 分子名称: | Hydrogen dependent carbon dioxide reductase subunit FdhF, Hydrogen dependent carbon dioxide reductase subunit HycB3, Hydrogen dependent carbon dioxide reductase subunit HycB4, ... | 著者 | Dietrich, H.M, Righetto, R.D, Kumar, A, Wietrzynski, W, Schuller, S.K, Trischler, R, Wagner, J, Schwarz, F.M, Engel, B.D, Mueller, V, Schuller, J.M. | 登録日 | 2022-01-19 | 公開日 | 2022-07-06 | 最終更新日 | 2022-08-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Membrane-anchored HDCR nanowires drive hydrogen-powered CO 2 fixation. Nature, 607, 2022
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7QSO
| Bovine complex I in lipid nanodisc, State 3 (Slack) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Chung, I, Bridges, H.R, Hirst, J. | 登録日 | 2022-01-13 | 公開日 | 2022-05-25 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
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7QSN
| Bovine complex I in lipid nanodisc, Deactive-apo | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Chung, I, Bridges, H.R, Hirst, J. | 登録日 | 2022-01-13 | 公開日 | 2022-05-25 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
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7QSM
| Bovine complex I in lipid nanodisc, Deactive-ligand (composite) | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Chung, I, Bridges, H.R, Hirst, J. | 登録日 | 2022-01-13 | 公開日 | 2022-05-25 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
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7QSL
| Bovine complex I in lipid nanodisc, Active-apo | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Chung, I, Bridges, H.R, Hirst, J. | 登録日 | 2022-01-13 | 公開日 | 2022-05-25 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (2.76 Å) | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
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7QSK
| Bovine complex I in lipid nanodisc, Active-Q10 | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Chung, I, Bridges, H.R, Hirst, J. | 登録日 | 2022-01-13 | 公開日 | 2022-05-25 | 最終更新日 | 2022-09-28 | 実験手法 | ELECTRON MICROSCOPY (2.84 Å) | 主引用文献 | Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy. Nat Commun, 13, 2022
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7QSD
| Bovine complex I in the active state at 3.1 A | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, Acyl carrier protein, ... | 著者 | Bridges, H.R, Blaza, J.N, Yin, Z, Chung, I, Hirst, J. | 登録日 | 2022-01-13 | 公開日 | 2022-03-02 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379, 2023
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7PSA
| The acetogenin-bound complex I of Mus musculus resolved to 3.4 angstroms | 分子名称: | (3~{S},5~{S})-5-methyl-3-[(13~{R})-13-oxidanyl-13-[(2~{R},5~{R})-5-[(2~{R},5~{R})-5-[(1~{R})-1-oxidanylundecyl]oxolan-2-yl]oxolan-2-yl]tridecyl]oxolan-2-one, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ... | 著者 | Grba, D, Hirst, J. | 登録日 | 2021-09-22 | 公開日 | 2022-04-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-electron microscopy reveals how acetogenins inhibit mitochondrial respiratory complex I. J.Biol.Chem., 298, 2022
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7P7M
| Complex I from E. coli, DDM/LMNG-purified, inhibited by Piericidin A, Open state | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | 登録日 | 2021-07-19 | 公開日 | 2022-09-21 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7L
| Complex I from E. coli, DDM/LMNG-purified, with NADH and FMN, Open state | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | 登録日 | 2021-07-19 | 公開日 | 2022-09-21 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7K
| Complex I from E. coli, DDM/LMNG-purified, with DQ, Resting state | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | 登録日 | 2021-07-19 | 公開日 | 2022-09-21 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7J
| Complex I from E. coli, DDM/LMNG-purified, with DQ, Open state | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, CALCIUM ION, ... | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | 登録日 | 2021-07-19 | 公開日 | 2022-09-21 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7E
| Complex I from E. coli, DDM/LMNG-purified, Apo, Resting state | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | 登録日 | 2021-07-19 | 公開日 | 2022-09-21 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P7C
| Complex I from E. coli, DDM/LMNG-purified, Apo, Open state | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CALCIUM ION, EICOSANE, ... | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | 登録日 | 2021-07-19 | 公開日 | 2022-09-21 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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7P69
| Complex I from E. coli, DDM/LMNG-purified, under Turnover at pH 6, Resting state | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, CALCIUM ION, ... | 著者 | Kravchuk, V, Kampjut, D, Sazanov, L. | 登録日 | 2021-07-15 | 公開日 | 2022-09-21 | 最終更新日 | 2022-10-05 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A universal coupling mechanism of respiratory complex I. Nature, 609, 2022
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