7R45

Bovine complex I in the presence of IM1761092, deactive class i (Composite map)

Summary for 7R45

Entry DOI	10.2210/pdb7r45/pdb
EMDB information	14272 14273 14274 14275 14276
Descriptor	NADH-ubiquinone oxidoreductase chain 3, NADH-ubiquinone oxidoreductase chain 6, NADH-ubiquinone oxidoreductase chain 4L, ... (60 entities in total)
Functional Keywords	complex i, oxidoreductase
Biological source	Bos taurus (cattle) More
Total number of polymer chains	45
Total formula weight	1076930.58
Authors	Bridges, H.R.,Blaza, J.N.,Yin, Z.,Chung, I.,Hirst, J. (deposition date: 2022-02-08, release date: 2023-02-08)
Primary citation	Bridges, H.R.,Blaza, J.N.,Yin, Z.,Chung, I.,Pollak, M.N.,Hirst, J. Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379:351-357, 2023 Cited by PubMed: 36701435 DOI: 10.1126/science.ade3332 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.4 Å)

Structure validation