7R4D

Bovine complex I in the presence of IM1761092, deactive class vi (Composite map)

Summary for 7R4D

• Entry DOI: 10.2210/pdb7r4d/pdb
• EMDB information: 14297 14298 14299 14300 14301
• Descriptor: NADH-ubiquinone oxidoreductase chain 3, NADH-ubiquinone oxidoreductase chain 6, NADH-ubiquinone oxidoreductase chain 4L, ... (60 entities in total)
• Functional Keywords: complex i, oxidoreductase
• Biological source: Bos taurus (cattle); More
• Total number of polymer chains: 45
• Total formula weight: 1074352.87

Authors

Bridges, H.R.,Blaza, J.N.,Yin, Z.,Chung, I.,Hirst, J. (deposition date: 2022-02-08, release date: 2023-02-08)

• Primary citation: Bridges, H.R.,Blaza, J.N.,Yin, Z.,Chung, I.,Pollak, M.N.,Hirst, J.; Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides.; Science, 379:351-357, 2023; PubMed: 36701435; DOI: 10.1126/science.ade3332

Experimental method

ELECTRON MICROSCOPY (2.3 Å)