7R44
Bovine complex I in the presence of IM1761092, active class iv (Composite map)
Summary for 7R44
| Entry DOI | 10.2210/pdb7r44/pdb |
| EMDB information | 14266 14267 14268 14269 14270 |
| Descriptor | NADH-ubiquinone oxidoreductase chain 3, NADH-ubiquinone oxidoreductase chain 6, NADH-ubiquinone oxidoreductase chain 4L, ... (60 entities in total) |
| Functional Keywords | complex i, oxidoreductase |
| Biological source | Bos taurus (cattle) More |
| Total number of polymer chains | 45 |
| Total formula weight | 1075660.00 |
| Authors | Bridges, H.R.,Blaza, J.N.,Yin, Z.,Chung, I.,Hirst, J. (deposition date: 2022-02-08, release date: 2023-02-08) |
| Primary citation | Bridges, H.R.,Blaza, J.N.,Yin, Z.,Chung, I.,Pollak, M.N.,Hirst, J. Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides. Science, 379:351-357, 2023 Cited by PubMed: 36701435DOI: 10.1126/science.ade3332 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.4 Å) |
Structure validation
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