PDB: 255 件ウェブページステータス検索Chemie searchBIRD

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2ANT	THE 2.6 A STRUCTURE OF ANTITHROMBIN INDICATES A CONFORMATIONAL CHANGE AT THE HEPARIN BINDING SITE 分子名称: 2-acetamido-2-deoxy-beta-D-allopyranose, ANTITHROMBIN 著者 Skinner, R, Abrahams, J.-P, Whisstock, J.C, Lesk, A.M, Carrell, R.W, Wardell, M.R. 登録日 1997-01-28 公開日 1997-06-16 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The 2.6 A structure of antithrombin indicates a conformational change at the heparin binding site. J.Mol.Biol., 266, 1997
2ARQ	Human plasminogen activator inhibitor-2.[loop (66-98) deletion mutant] complexed with peptide n-acetyl-teaaagdggvmtgr-oh 分子名称: 14-mer from Plasminogen activator inhibitor-2, Plasminogen activator inhibitor-2 著者 Di Giusto, D.A, Sutherland, A.P, Jankova, L, Harrop, S.J, Curmi, P.M, King, G.C. 登録日 2005-08-21 公開日 2006-07-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution--implications for serpin mechanistic model and prediction of nsSNP activities J.Mol.Biol., 353, 2005
2B4X	Crystal Structure of Antithrombin-III 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III 著者 Adams, T.E, Huntington, J.A, Johnson, D.J.D, Bock, S.C. 登録日 2005-09-27 公開日 2006-10-10 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal Structure of Antithrombin-III To be Published
2ARR	Human plasminogen activator inhibitor-2.[loop (66-98) deletion mutant] complexed with peptide n-acetyl-teaaagmggvmtgr-oh 分子名称: 14-mer from Plasminogen activator inhibitor-2, Plasminogen activator inhibitor-2 著者 Di Giusto, D.A, Sutherland, A.P, Jankova, L, Harrop, S.J, Curmi, P.M, King, G.C. 登録日 2005-08-21 公開日 2006-07-11 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution--implications for serpin mechanistic model and prediction of nsSNP activities J.Mol.Biol., 353, 2005
5NBV	Crystal structure of native alpha-1-antitrypsin with seven stabilising mutations 分子名称: Alpha-1-antitrypsin, GLYCEROL 著者 Huntington, J.A, Pomowski, A, Johnson, D.J.D. 登録日 2017-03-02 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 CRYSTAL STRUCTURE OF THE Z VARIANT OF ALPHA-1-ANTITRYPSIN REVEALS STRUCTURAL AND DYNAMICAL CHANGES AND SUPPORTS A C-TERMINAL DOMAIN SWAP MECHANISM OF POLYMERIZATION To Be Published
5NBU	Crystal structure of native alpha-1-antitrypsin with seven stabilising mutations 分子名称: Alpha-1-antitrypsin, GLYCEROL, OXAMIC ACID 著者 Huntington, J.A, Pomowski, A, Johnson, D.J.D. 登録日 2017-03-02 公開日 2018-03-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 CRYSTAL STRUCTURE OF THE Z VARIANT OF ALPHA-1-ANTITRYPSIN REVEALS STRUCTURAL AND DYNAMICAL CHANGES AND SUPPORTS A C-TERMINAL DOMAIN SWAP MECHANISM OF POLYMERIZATION To Be Published
4AU4	Crystal Structure of Hsp47 分子名称: SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), MEMBER 1, ... 著者 Widmer, C, Gebauer, J.M, Brunstein, E, Rodenbaum, S, Zaucke, F, Drogemuller, C, Leeb, T, Baumann, U. 登録日 2012-05-14 公開日 2012-08-15 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.97 Å) 主引用文献 Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012
5NCT	Structure of the trypsin induced serpin-type proteinase inhibitor, miropin. 分子名称: ASPARTIC ACID, GLYCEROL, SERINE, ... 著者 Goulas, T, Ksiazek, M, Garcia-Ferrer, I, Mizgalska, D, Potempa, J, Gomis-Ruth, X. 登録日 2017-03-06 公開日 2017-05-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome. J. Biol. Chem., 292, 2017
5NCU	Structure of the subtilisin induced serpin-type proteinase inhibitor, miropin. 分子名称: CHLORIDE ION, GLYCEROL, IODIDE ION, ... 著者 Goulas, T, Ksiazek, M, Garcia-Ferrer, I, Mizgalska, D, Potempa, J, Gomis-Ruth, X. 登録日 2017-03-06 公開日 2017-05-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome. J. Biol. Chem., 292, 2017
4CAA	CLEAVED ANTICHYMOTRYPSIN T345R 分子名称: ANTICHYMOTRYPSIN 著者 Lukacs, C.M, Christianson, D.W. 登録日 1997-08-14 公開日 1998-02-25 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction. Biochemistry, 37, 1998
4DY0	Crystal structure of native protease nexin-1 with heparin 分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, GLYCEROL, Glia-derived nexin, ... 著者 Huntington, J.A, Li, W. 登録日 2012-02-28 公開日 2012-08-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structures of protease nexin-1 in complex with heparin and thrombin suggest a 2-step recognition mechanism. Blood, 120, 2012
4BB2	Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone 分子名称: 1,2-ETHANEDIOL, CORTICOSTEROID-BINDING GLOBULIN, CYSTEINE, ... 著者 Gardill, B.R, Vogl, M.R, Lin, H, Hammond, G.L, Muller, Y.A. 登録日 2012-09-19 公開日 2012-12-26 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.48 Å) 主引用文献 Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences Plos One, 7, 2012
4AU2	Crystal Structure of a Hsp47-collagen complex 分子名称: 15ER COLLAGEN MODEL PEPTIDE 15-R8, SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), ... 著者 Widmer, C, Gebauer, J.M, Brunstein, E, Drogemuller, C, Leeb, T, Baumann, U. 登録日 2012-05-13 公開日 2012-08-15 最終更新日 2015-04-01 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition. Proc.Natl.Acad.Sci.USA, 109, 2012
5M3X	Crystal structure of human angiotensin I-deleted angiotensinogen 分子名称: Angiotensinogen 著者 Yan, Y, Read, R.J. 登録日 2016-10-17 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.63 Å) 主引用文献 Structural basis for the specificity of renin-mediated angiotensinogen cleavage. J. Biol. Chem., 294, 2019
5NCW	Structure of the trypsin induced serpin-type proteinase inhibitor, miropin (V367K/K368A mutant). 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, GLYCEROL, ... 著者 Goulas, T, Ksiazek, M, Garcia-Ferrer, I, Mizgalska, D, Potempa, J, Gomis-Ruth, X. 登録日 2017-03-06 公開日 2017-05-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome. J. Biol. Chem., 292, 2017
5NCS	Structure of the native serpin-type proteinase inhibitor, miropin. 分子名称: Serpin 著者 Goulas, T, Ksiazek, M, Garcia-Ferrer, I, Mizgalska, D, Potempa, J, Gomis-Ruth, X. 登録日 2017-03-06 公開日 2017-05-24 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A structure-derived snap-trap mechanism of a multispecific serpin from the dysbiotic human oral microbiome. J. Biol. Chem., 292, 2017
5M3Y	Crystal structure of human glycosylated angiotensinogen 分子名称: Angiotensinogen, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Yan, Y, Read, R.J. 登録日 2016-10-17 公開日 2017-12-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural basis for the specificity of renin-mediated angiotensinogen cleavage. J. Biol. Chem., 294, 2019
5OM6	Crystal structure of Alpha1-antichymotrypsin variant DBS-I-allo2: a MMP9-cleavable drug-binding serpin for doxycycline 分子名称: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, CHLORIDE ION, ... 著者 Schmidt, K, Muller, Y.A. 登録日 2017-07-28 公開日 2018-05-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5OM8	Crystal form 2 of Alpha1-antichymotrypsin variant DBS-II-allo: an allosterically modulated drug-binding serpin for doxorubicin 分子名称: 1,2-ETHANEDIOL, Alpha-1-antichymotrypsin, CHLORIDE ION, ... 著者 Schmidt, K, Muller, Y.A. 登録日 2017-07-28 公開日 2018-05-23 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Design of an allosterically modulated doxycycline and doxorubicin drug-binding protein. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
4C49	Reactive loop cleaved human CBG in complex with cortisol 分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN 著者 Chan, W.L, Zhou, A, Read, R.J. 登録日 2013-09-02 公開日 2014-10-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Role of Sa-Hd Loop Movement in Cortisol Release Mechanism of Cbg To be Published
4C41	Corticosteroid-binding globulin with engineered disulphide bridge between residues 100 and 236 分子名称: CORTICOSTEROID-BINDING GLOBULIN 著者 Chan, W.L, Zhou, A, Read, R.J. 登録日 2013-08-28 公開日 2014-10-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Towards Engineering Hormone-Binding Globulins as Drug Delivery Agents. Plos One, 9, 2014
4DTE	Crystal structure of zebrafish plasminogen activator inhibitor-1 (PAI-1) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Serpin peptidase inhibitor, clade E (nexin, ... 著者 Johansen, J.S. 登録日 2012-02-21 公開日 2013-03-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.96 Å) 主引用文献 Protein conformational change delayed by steric hindrance from an N-linked glycan. J.Mol.Biol., 425, 2013
4EB1	Hyperstable in-frame insertion variant of antithrombin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III 著者 Martinez-Martinez, I, Johnson, D.J.D, Yamasaki, M, Corral, J, Huntington, J.A. 登録日 2012-03-23 公開日 2012-07-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Type II antithrombin deficiency caused by a large in-frame insertion: structural, functional and pathological relevance. J.Thromb.Haemost., 10, 2012
1PSI	Intact recombined alpha1-antitrypsin mutant PHE 51 to LEU 分子名称: ALPHA=1=-ANTITRYPSIN 著者 Abrahams, J.P, Elliott, P.R, Lomas, D.A, Carrell, R.W. 登録日 1996-06-11 公開日 1996-12-07 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Inhibitory conformation of the reactive loop of alpha 1-antitrypsin. Nat.Struct.Biol., 3, 1996
1OVA	CRYSTAL STRUCTURE OF UNCLEAVED OVALBUMIN AT 1.95 ANGSTROMS RESOLUTION 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, OVALBUMIN 著者 Stein, P.E, Leslie, A.G.W. 登録日 1990-11-26 公開日 1992-04-15 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Crystal structure of uncleaved ovalbumin at 1.95 A resolution. J.Mol.Biol., 221, 1991

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