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1UHG
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Crystal Structure of S-Ovalbumin At 1.9 Angstrom Resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ovalbumin, ...
著者Yamasaki, M, Takahashi, N, Hirose, M.
登録日2003-07-03
公開日2003-07-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of S-ovalbumin as a Non-loop-inserted Thermostabilized Serpin Form
J.Biol.Chem., 278, 2003
1T1F
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BU of 1t1f by Molmil
Crystal Structure of Native Antithrombin in its Monomeric Form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antithrombin-III, GLYCEROL, ...
著者Johnson, D.J.D, Huntington, J.A.
登録日2004-04-16
公開日2005-10-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structure of monomeric native antithrombin reveals a novel reactive center loop conformation
J.Biol.Chem., 281, 2006
2ZV6
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Crystal structure of human squamous cell carcinoma antigen 1
分子名称: Serpin B3
著者Zheng, B, Matoba, Y, Katagiri, C, Hibino, T, Sugiyama, M.
登録日2008-11-01
公開日2009-02-24
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of SCCA1 and insight about the interaction with JNK1
Biochem.Biophys.Res.Commun., 380, 2009
2ARQ
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BU of 2arq by Molmil
Human plasminogen activator inhibitor-2.[loop (66-98) deletion mutant] complexed with peptide n-acetyl-teaaagdggvmtgr-oh
分子名称: 14-mer from Plasminogen activator inhibitor-2, Plasminogen activator inhibitor-2
著者Di Giusto, D.A, Sutherland, A.P, Jankova, L, Harrop, S.J, Curmi, P.M, King, G.C.
登録日2005-08-21
公開日2006-07-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Plasminogen activator inhibitor-2 is highly tolerant to P8 residue substitution--implications for serpin mechanistic model and prediction of nsSNP activities
J.Mol.Biol., 353, 2005
3CAA
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CLEAVED ANTICHYMOTRYPSIN A347R
分子名称: ANTICHYMOTRYPSIN
著者Lukacs, C.M, Christianson, D.W.
登録日1997-08-18
公開日1998-02-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction.
Biochemistry, 37, 1998
3CVM
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BU of 3cvm by Molmil
High resolution structure of a stable Plasminogen activator inhibitor type-1 in its protease cleaved form
分子名称: Plasminogen activator inhibitor 1
著者Jensen, J.K, Gettins, P.G.W.
登録日2008-04-18
公開日2008-08-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献High-resolution structure of the stable plasminogen activator inhibitor type-1 variant 14-1B in its proteinase-cleaved form: a new tool for detailed interaction studies and modeling.
Protein Sci., 17, 2008
3CWL
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BU of 3cwl by Molmil
Crystal structure of alpha-1-antitrypsin, crystal form B
分子名称: Alpha-1-antitrypsin, CHLORIDE ION
著者Morton, C.J, Hansen, G, Feil, S.C, Adams, J.J, Parker, M.W.
登録日2008-04-22
公開日2008-09-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding.
Protein Sci., 17, 2008
3CWM
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Crystal structure of alpha-1-antitrypsin complexed with citrate
分子名称: Alpha-1-antitrypsin, CITRIC ACID
著者Morton, C.J, Hansen, G, Feil, S.C, Adams, J.J, Parker, M.W.
登録日2008-04-22
公開日2008-09-23
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding.
Protein Sci., 17, 2008
3DRU
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Crystal Structure of Gly117Phe Alpha1-Antitrypsin
分子名称: Alpha-1-antitrypsin
著者Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E.
登録日2008-07-11
公開日2009-03-31
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design.
J.Mol.Biol., 387, 2009
3DRM
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2.2 Angstrom Crystal Structure of Thr114Phe Alpha1-Antitrypsin
分子名称: Alpha-1-antitrypsin
著者Gooptu, B, Nobeli, I, Purkiss, A, Phillips, R.L, Mallya, M, Lomas, D.A, Barrett, T.E.
登録日2008-07-11
公開日2009-03-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystallographic and cellular characterisation of two mechanisms stabilising the native fold of alpha1-antitrypsin: implications for disease and drug design.
J.Mol.Biol., 387, 2009
3DLW
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BU of 3dlw by Molmil
Antichymotrypsin
分子名称: Alpha-1-antichymotrypsin
著者Feil, S.C.
登録日2008-06-29
公開日2009-07-07
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Identification and characterization of a misfolded monomeric serpin formed at physiological temperature
J.Mol.Biol., 403, 2010
3DY0
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BU of 3dy0 by Molmil
Crystal Structure of Cleaved PCI Bound to Heparin
分子名称: 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid, C-terminus Plasma serine protease inhibitor, GLYCEROL, ...
著者Li, W, Huntington, J.A.
登録日2008-07-25
公開日2008-10-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The heparin binding site of protein C inhibitor is protease-dependent.
J.Biol.Chem., 283, 2008
3EOX
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High quality structure of cleaved PAI-1-stab
分子名称: Plasminogen activator inhibitor 1
著者Dewilde, M, Declerck, P.J, Rabijns, A, Strelkov, S.V.
登録日2008-09-29
公開日2009-02-17
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献High quality structure of cleaved PAI-1-stab.
J.Struct.Biol., 165, 2009
3EVJ
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BU of 3evj by Molmil
Intermediate structure of antithrombin bound to the natural pentasaccharide
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-beta-D-glucopyranuronic acid-(1-4)-2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-methyl 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranoside, ...
著者Huntington, J.A, Belzar, K.J.
登録日2008-10-13
公開日2008-10-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The critical role of hinge-region expulsion in the induced-fit heparin binding mechanism of antithrombin.
J. Mol. Biol., 386, 2009
4AJT
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BU of 4ajt by Molmil
The crystal structure of mouse protein-Z dependent protease inhibitor(mZPI)
分子名称: PROTEIN Z-DEPENDENT PROTEASE INHIBITOR
著者Yan, Y, Zhou, A.
登録日2012-02-19
公開日2012-12-05
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z.
Blood, 120, 2012
4AU4
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BU of 4au4 by Molmil
Crystal Structure of Hsp47
分子名称: SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), MEMBER 1, ...
著者Widmer, C, Gebauer, J.M, Brunstein, E, Rodenbaum, S, Zaucke, F, Drogemuller, C, Leeb, T, Baumann, U.
登録日2012-05-14
公開日2012-08-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AU2
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Crystal Structure of a Hsp47-collagen complex
分子名称: 15ER COLLAGEN MODEL PEPTIDE 15-R8, SERPIN PEPTIDASE INHIBITOR, CLADE H (HEAT SHOCK PROTEIN 47), ...
著者Widmer, C, Gebauer, J.M, Brunstein, E, Drogemuller, C, Leeb, T, Baumann, U.
登録日2012-05-13
公開日2012-08-15
最終更新日2015-04-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition.
Proc.Natl.Acad.Sci.USA, 109, 2012
4BB2
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BU of 4bb2 by Molmil
Crystal structure of cleaved corticosteroid-binding globulin in complex with progesterone
分子名称: 1,2-ETHANEDIOL, CORTICOSTEROID-BINDING GLOBULIN, CYSTEINE, ...
著者Gardill, B.R, Vogl, M.R, Lin, H, Hammond, G.L, Muller, Y.A.
登録日2012-09-19
公開日2012-12-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences
Plos One, 7, 2012
4AJU
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BU of 4aju by Molmil
Crystal structure of the reactive loop cleaved ZPI in P41 space group
分子名称: 1,2-ETHANEDIOL, PROTEIN Z-DEPENDENT PROTEASE INHIBITOR, SULFATE ION
著者Zhou, A, Yan, Y, Wei, Z.
登録日2012-02-19
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z.
Blood, 120, 2012
4CAA
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CLEAVED ANTICHYMOTRYPSIN T345R
分子名称: ANTICHYMOTRYPSIN
著者Lukacs, C.M, Christianson, D.W.
登録日1997-08-14
公開日1998-02-25
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Engineering an anion-binding cavity in antichymotrypsin modulates the "spring-loaded" serpin-protease interaction.
Biochemistry, 37, 1998
4C49
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BU of 4c49 by Molmil
Reactive loop cleaved human CBG in complex with cortisol
分子名称: (11alpha,14beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, CORTICOSTEROID-BINDING GLOBULIN
著者Chan, W.L, Zhou, A, Read, R.J.
登録日2013-09-02
公開日2014-10-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Role of Sa-Hd Loop Movement in Cortisol Release Mechanism of Cbg
To be Published
3ZHA
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Molecular basis for the action of the collagen-specific chaperone Hsp47 SERPINH1 and its structure-specific client recognition.
分子名称: COLLAGEN MODEL PEPTIDE 18-T8R11, HSP47, SUCCINIC ACID
著者Widmer, C, Gebauer, J.M, Baumann, U.
登録日2012-12-20
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Molecular Basis for the Action of the Collagen-Specific Chaperone Hsp47/Serpinh1 and its Structure-Specific Client Recognition.
Proc.Natl.Acad.Sci.USA, 109, 2012
4AQH
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Plasminogen activator inhibitor type-1 in complex with the inhibitor AZ3976
分子名称: PLASMINOGEN ACTIVATOR INHIBITOR 1, TERT-BUTYL 3-[(4-OXO-3H-PYRIDO[2,3-D]PYRIMIDIN-2-YL)AMINO]AZETIDINE-1-CARBOXYLATE
著者Fjellstrom, O, Deinum, J, Sjogren, T, Johansson, C, Geschwindner, S, Nerme, V, Legnehed, A, McPheat, J, Olsson, K, Bodin, C, Gustafsson, D.
登録日2012-04-17
公開日2012-11-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Characterization of a Small Molecule Inhibitor of Plasminogen Activator Inhibitor Type 1 that Accelerates the Transition Into the Latent Conformation
J.Biol.Chem., 288, 2013
4AFX
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Crystal structure of the reactive loop cleaved ZPI in I2 space group
分子名称: CALCIUM ION, PHOSPHATE ION, PROTEIN Z DEPENDENT PROTEASE INHIBITOR, ...
著者Zhou, A, Yan, Y, Wei, Z.
登録日2012-01-23
公開日2013-01-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural Basis for Catalytic Activation of Protein Z-Dependent Protease Inhibitor (Zpi) by Protein Z.
Blood, 120, 2012
4C41
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Corticosteroid-binding globulin with engineered disulphide bridge between residues 100 and 236
分子名称: CORTICOSTEROID-BINDING GLOBULIN
著者Chan, W.L, Zhou, A, Read, R.J.
登録日2013-08-28
公開日2014-10-01
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Towards Engineering Hormone-Binding Globulins as Drug Delivery Agents.
Plos One, 9, 2014

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